Research Letter May 13, 2022 Risk of Infection and Hospitalization Among Vaccinated and Unvaccinated Children and Adolescents in New York After the Emergence of the Omicron Variant Vajeera Dorabawila, Dina Hoefer, Ursula E. Bauer, et al JAMA. Published online May 13, 2022. doi:10.1001/jama.2022.7319 In the US, 12.3 million youth aged 18 years and younger were diagnosed with COVID-19 by April 7, 2022.1 Studies conducted before the Omicron variant...

COMMENT|ONLINE FIRST What a second booster dose of mRNA COVID-19 vaccines tells us Paul Loubet, Odile Launay Lancet Infect Dis May 09, 2022 DOI:https://doi.org/10.1016/S1473-3099(22)00282-1 Real-world studies have shown waning vaccine effectiveness against both SARS-CoV-2 infection and COVID-19-related hospitalisation within 2·5 months after a first booster dose of COVID-19 mRNA vaccine, especially for the SARS-CoV-2 omicron (B.1.1.529) variant. 1Several...

ARTICLES|ONLINE FIRST Measuring the availability of human resources for health and its relationship to universal health coverage for 204 countries and territories from 1990 to 2019: a systematic analysis for the Global Burden of Disease Study 2019 GBD 2019 Human Resources for Health Collaborators Lancet 2022 Published: May 23, 2022 DOI:https://doi.org/10.1016/S0140-6736(22)00532-3 Summary Background Human resources for health (HRH) include a range of ...

Original Investigation May 13, 2022 Association of Prior BNT162b2 COVID-19 Vaccination With Symptomatic SARS-CoV-2 Infection in Children and Adolescents During Omicron Predominance Katherine E. Fleming-Dutra, Amadea Britton, Nong Shang, et al JAMA. Published online May 13, 2022. doi:10.1001/jama.2022.7493 Key Points Question  Does the estimated effectiveness of 2 doses of the BNT162b2 COVID-19 vaccine against symptomatic SARS-CoV-2 ...

ARTICLES|ONLINE FIRST Safety, immunogenicity, and reactogenicity of BNT162b2 and mRNA-1273 COVID-19 vaccines given as fourth-dose boosters following two doses of ChAdOx1 nCoV-19 or BNT162b2 and a third dose of BNT162b2 (COV-BOOST): a multicentre, blinded, phase 2, randomised trial Alasdair P S Munro, Shuo Feng, Leila Janani, et al Lancet Infect Dis Published:May 09, 2022 DOI:https://doi.org/10.1016/S1473-3099(22)00271-7 Summary Background Some high-in...

ARTICLES| VOLUME 399, ISSUE 10340, P2047-2064, MAY 28, 2022 Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in children younger than 5 years in 2019: a systematic analysis You Li, Xin Wang, Dianna M Blau, et al Lancet 2022; 399: 2047-2064 Summary Background Respiratory syncytial virus (RSV) is the most common cause of acute lower respiratory infection in young...

ARTICLES|ONLINE FIRST Venous or arterial thrombosis and deaths among COVID-19 cases: a European network cohort study Edward Burn, Talita Duarte-Salles, Sergio Fernandez-Bertolin, et al Lancet Infect Dis Published:May 13, 2022 DOI:https://doi.org/10.1016/S1473-3099(22)00223-7 Summary Background There are few data on the incidence of thrombosis among COVID-19 cases, with most research concentrated on hospitalised patients. We aimed to estimate the incid...

Original Investigation May 15, 2022 Effect of Robot-Assisted Radical Cystectomy With Intracorporeal Urinary Diversion vs Open Radical Cystectomy on 90-Day Morbidity and Mortality Among Patients With Bladder Cancer: A Randomized Clinical Trial James W. F. Catto, Pramit Khetrapal, Federico Ricciardi, et al JAMA. Published online May 15, 2022. doi:10.1001/jama.2022.7393 Key Points Question  Does robot-assisted surgery improve periopera...

CORRESPONDENCE Omicron BA.1/1.1 SARS-CoV-2 Infection among Vaccinated Canadian Adults Patrick E. Brown, Sze Hang Fu, Aiyush Bansal, et al N Engl J Med May 18, 2022DOI: 10.1056/NEJMc2202879 TO THE EDITOR: The incidence of the omicron BA.1/1.1 variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which rapidly spread worldwide even among vaccinated persons, is incompletely defined.1 We quantified the incidence of SARS-CoV-2 infection d...

ARTICLES|ONLINE FIRST Alcoholic chlorhexidine skin preparation or triclosan-coated sutures to reduce surgical site infection: a systematic review and meta-analysis of high-quality randomised controlled trials National Institute of Health Research Unit on Global Surgery Lancet Infect Dis Published:May 26, 2022 DOI:https://doi.org/10.1016/S1473-3099(22)00133-5 Summary Background WHO and the UK's National Institute for Health and Care Excellence recommen...