Original Investigation  Caring for the Critically Ill Patient June 27, 2022 Effect of Nitric Oxide via Cardiopulmonary Bypass on Ventilator-Free Days in Young Children Undergoing Congenital Heart Disease Surgery: The NITRIC Randomized Clinical Trial Luregn J. Schlapbach, Kristen S. Gibbons, Stephen B. Horton, et al JAMA. Published online June 27, 2022. doi:10.1001/jama.2022.9376 Key Points Question  Does nitric oxide applied i...

Research Industry sponsorship bias in cost effectiveness analysis: registry based analysis Feng Xie, Ting Zhou BMJ 2022; 377 doi: https://doi.org/10.1136/bmj-2021-069573 (Published 22 June 2022)Cite this as: BMJ 2022;377:e069573 Abstract Objective To assess the association between industry sponsorship (drug, medical device, and biotechnology companies) and cost effectiveness results in cost effectiveness analysis (CEA). Design Registry based an...

Brief Report  November 19, 2020 Eye Protection for Patients With COVID-19 Undergoing Prolonged Prone-Position Ventilation Lucy Sun, Maggie Hymowitz, Howard D. Pomeranz JAMA Ophthalmol. 2021;139(1):109-112. doi:10.1001/jamaophthalmol.2020.4988 Key Points Question  What ophthalmic abnormalities are present in patients with coronavirus disease 2019 in the intensive care unit requiring prolonged prone-position ventilation? Findings &nb...

Research Special Paper Political environment and mortality rates in the United States, 2001-19: population based cross sectional analysis Haider J Warraich, Pankaj Kumar, Khurram Nasir, et al BMJ 2022; 377 doi: https://doi.org/10.1136/bmj-2021-069308 (Published 07 June 2022)Cite this as: BMJ 2022;377:e069308 Abstract Objective To assess recent trends in age adjusted mortality rates (AAMRs) in the United States based on county level presidential vo...

ARTICLES| VOLUME 399, ISSUE 10344, P2351-2380, JUNE 25, 2022 Estimating global, regional, and national daily and cumulative infections with SARS-CoV-2 through Nov 14, 2021: a statistical analysis COVID-19 Cumulative Infection Collaborators Lancet 2022; 399: 2351-2380 Published:April 08, 2022 DOI:https://doi.org/10.1016/S0140-6736(22)00484-6 Summary Background Timely, accurate, and comprehensive estimates of SARS-CoV-2 daily infection ra...

US Preventive Services Task Force  Evidence Report June 21, 2022 Vitamin and Mineral Supplements for the Primary Prevention of Cardiovascular Disease and Cancer: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force Elizabeth A. O’Connor, Corinne V. Evans, Ilya Ivlev, et al JAMA. 2022;327(23):2334-2347. doi:10.1001/jama.2021.15650 Abstract Importance  Cardiovascular disease and cancer are the ...

Research Development and validation of a decision support tool for the diagnosis of acute heart failure: systematic review, meta-analysis, and modelling study Kuan Ken Lee, Dimitrios Doudesis, Mohamed Anwar, et al BMJ 2022; 377 doi: https://doi.org/10.1136/bmj-2021-068424 (Published 13 June 2022)Cite this as: BMJ 2022;377:e068424 Abstract Objectives To evaluate the diagnostic performance of N-terminal pro-B-...

Research Letter  June 2, 2022 Association Between COVID-19 Booster Vaccination and Omicron Infection in a Highly Vaccinated Cohort of Players and Staff in the National Basketball Association Caroline G. Tai, Lisa L. Maragakis, Sarah Connolly, et al JAMA. Published online June 2, 2022. doi:10.1001/jama.2022.9479 Evaluation of COVID-19 vaccine booster effectiveness is essential as new variants of SARS-CoV-2 emerge. Data support the effectivenes...

This is an officialCDC HEALTH ADVISORY Distributed via the CDC Health Alert Network May 24, 2022, 9:00 AM ETCDCHAN-0467 COVID-19 Rebound After Paxlovid Treatment Summary The Centers for Disease Control and Prevention (CDC) is issuing this Health Alert Network (HAN) Health Advisory to update healthcare providers, public health departments, and the public on the potential for recurrence of COVID-19 or “COVID-19 rebound.” Paxlovid continues to be recomm...

Original Investigation  June 4, 2022 Effect of Intraoperative Handovers of Anesthesia Care on Mortality, Readmission, or Postoperative Complications Among Adults: The HandiCAP Randomized Clinical Trial Melanie Meersch, Raphael Weiss, Mira Küllmar, et al JAMA. Published online June 4, 2022. doi:10.1001/jama.2022.9451 Key Points Question  Among adults undergoing extended surgical procedures, what is the effect of an intraoperative ...