Original Investigation  September 27, 2022 Effect of High-Flow Nasal Cannula Oxygen vs Standard Oxygen Therapy on Mortality in Patients With Respiratory Failure Due to COVID-19: The SOHO-COVID Randomized Clinical Trial Jean-Pierre Frat, Jean-Pierre Quenot, Julio Badie, et al JAMA. 2022;328(12):1212-1222. doi:10.1001/jama.2022.15613 Key Points Questions  In patients with respiratory failure due to COVID-19, does the use of high-fl...

CORRESPONDENCE IL-1RA Antibodies in Myocarditis after SARS-CoV-2 Vaccination Lorenz Thurner, Christoph Kessel, Natalie Fadle, et al N Engl J Med September 21, 2022DOI: 10.1056/NEJMc2205667 TO THE EDITOR: Myocarditis associated with messenger RNA (mRNA) vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) predominantly affects male adolescents and young male adults (14 to <30 years of age) and typically occurs after receipt of the...

Original Investigation  September 20, 2022 Effect of Helmet Noninvasive Ventilation vs Usual Respiratory Support on Mortality Among Patients With Acute Hypoxemic Respiratory Failure Due to COVID-19: The HELMET-COVID Randomized Clinical Trial Yaseen M. Arabi, Sara Aldekhyl, Saad Al Qahtani, et al JAMA. 2022;328(11):1063-1072. doi:10.1001/jama.2022.15599 Key Points Question  What is the effect of noninvasive ventilation delivered b...

Research Efficacy and safety of extended duration to perioperative thromboprophylaxis with low molecular weight heparin on disease-free survival after surgical resection of colorectal cancer (PERIOP-01): multicentre, open label, randomised controlled trial Rebecca C Auer, Michael Ott, Paul Karanicolas, et al BMJ 2022; 378 doi: https://doi.org/10.1136/bmj-2022-071375 (Published 13 September 2022)Cite this as: BMJ 2022;378:e071375 Abstract Objective To d...

Research Associations of physician burnout with career engagement and quality of patient care: systematic review and meta-analysis Alexander Hodkinson, Anli Zhou, Judith Johnson, et al BMJ 2022; 378 doi: https://doi.org/10.1136/bmj-2022-070442 (Published 14 September 2022)Cite this as: BMJ 2022;378:e070442 Abstract Objective To examine the association of physician burnout with the career engagement and the quality of patient care globally. Design&nb...

Research Diagnostic accuracy of covid-19 rapid antigen tests with unsupervised self-sampling in people with symptoms in the omicron period: cross sectional study Ewoud Schuit, Roderick P Venekamp, Lotty Hooft, et al BMJ 2022; 378 doi: https://doi.org/10.1136/bmj-2022-071215 (Published 14 September 2022)Cite this as: BMJ 2022;378:e071215 Abstract Objective To assess the performance of rapid antigen tests with unsupervised nasal and combined oropharyngea...

CHEST INFECTIONS: ORIGINAL RESEARCH| VOLUME 162, ISSUE 3, P543-555, SEPTEMBER 01, 2022 Influenza Testing and Treatment Among Patients Hospitalized With Community-Acquired Pneumonia Abhishek Deshpande, Michael Klompas, Pei-Chun Yu, et al Chest 2022; 162: 543-555 Published:February 05, 2022 DOI:https://doi.org/10.1016/j.chest.2022.01.053 Background Influenza is a leading cause of community-acquired pneumonia (CAP), and results of influenza t...

Original Investigation  June 1, 2022 Using Artificial Intelligence to Find the Optimal Margin Width in Hepatectomy for Colorectal Cancer Liver Metastases Dimitris Bertsimas, Georgios Antonios Margonis, Suleeporn Sujichantararat, et al JAMA Surg. 2022;157(8):e221819. doi:10.1001/jamasurg.2022.1819 Key Points Question  What is the optimal margin width for hepatectomy for colorectal cancer liver metastases and should it be individualized base...

Original Investigation  September 7, 2022 Bihormonal Artificial Pancreas With Closed-Loop Glucose Control vs Current Diabetes Care After Total Pancreatectomy: A Randomized Clinical Trial Charlotte L. van Veldhuisen, Anouk E. J. Latenstein, Helga Blauw, et al JAMA Surg. Published online September 7, 2022. doi:10.1001/jamasurg.2022.3702 Key Points Question  What is the efficacy and safety of the novel bihormonal artificial pancreas...

Original Investigation  June 8, 2022 Association Between Implementation of a Geriatric Trauma Clinical Pathway and Changes in Rates of Delirium in Older Adults With Traumatic Injury Caroline Park, Ankur Bharija, Matthew Mesias, et al JAMA Surg. 2022;157(8):676-683. doi:10.1001/jamasurg.2022.1556 Key Points Question  Is the establishment of a geriatric-centered clinical pathway associated with improved outcomes in older adults with traumati...