ARTICLES|ONLINE FIRST Effectiveness and durability of BNT162b2 vaccine against hospital and emergency department admissions due to SARS-CoV-2 omicron sub-lineages BA.1 and BA.2 in a large health system in the USA: a test-negative, case-control study Sara Y Tartof, Jeff M Slezak, Laura Puzniak, et al Lancet Respir Med Published:October 07, 2022 DOI:https://doi.org/10.1016/S2213-2600(22)00354-X Summary Background The SARS-CoV-2 omicron (B.1.1.529 BA.1) ...

ARTICLES|ONLINE FIRST Transfusion practice in patients receiving VV ECMO (PROTECMO): a prospective, multicentre, observational study Gennaro Martucci, Matthieu Schmidt, Cara Agerstrand, et al. Lancet Respir Med Published:October 11, 2022 DOI:https://doi.org/10.1016/S2213-2600(22)00353-8 Summary Background In patients receiving venovenous (VV) extracorporeal membrane oxygenation (ECMO) packed red blood cell (PRBC) transfusion thresholds are usually hig...

ARTICLES|ONLINE FIRST Prognostic factors associated with mortality among patients receiving venovenous extracorporeal membrane oxygenation for COVID-19: a systematic review and meta-analysis Alexandre Tran, Shannon M Fernando, Bram Rochwerg, et al. Lancet Respir Med Published: October 10, 2022 DOI: https://doi.org/10.1016/S2213-2600(22)00296-X Summary Background Venovenous extracorporeal membrane oxygenation (ECMO) can be considered for patients with ...

ARTICLES|ONLINE FIRST The burden of respiratory syncytial virus in healthy term-born infants in Europe: a prospective birth cohort study Joanne G Wildenbeest, Marie-Noëlle Billard, Roy P Zuurbier, et al. Lancet Respir Med Published:November 10, 2022 DOI:https://doi.org/10.1016/S2213-2600(22)00414-3 Summary Background Respiratory syncytial virus (RSV) is a major cause of hospitalisation in infants. The burden of RSV infection in healthy term infants ha...

ARTICLES|ONLINE FIRST In-hospital and 6-month outcomes in patients with COVID-19 supported with extracorporeal membrane oxygenation (EuroECMO-COVID): a multicentre, prospective observational study Roberto Lorusso, Maria Elena De Piero, Silvia Mariani, et al. Lancet Respir Med Published:November 16, 2022 DOI:https://doi.org/10.1016/S2213-2600(22)00403-9 Summary Background Extracorporeal membrane oxygenation (ECMO) has been widely used in patients with ...

ARTICLES|ONLINE FIRST Favipiravir in patients hospitalised with COVID-19 (PIONEER trial): a multicentre, open-label, phase 3, randomised controlled trial of early intervention versus standard care Pallav L Shah, Christopher M Orton, Beatriz Grinsztejn, et al. Lancet Respir Med Published:December 14, 2022 DOI:https://doi.org/10.1016/S2213-2600(22)00412-X Summary Background COVID-19 has overwhelmed health services globally. Oral antiviral therapies are ...

ARTICLES|ONLINE FIRST Comparative outcomes of extracorporeal membrane oxygenation for COVID-19 delivered in experienced European centres during successive SARS-CoV-2 variant outbreaks (ECMO-SURGES): an international, multicentre, retrospective cohort study Matthieu Schmidt, David Hajage, Micha Landoll, et al. Lancet Respir Med Published:January 11, 2023 DOI:https://doi.org/10.1016/S2213-2600(22)00438-6 Summary Background To inform future research and ...

ARTICLES|ONLINE FIRST Effect of early mobilisation on long-term cognitive impairment in critical illness in the USA: a randomised controlled trial Bhakti K Patel, Krysta S Wolfe, Shruti B Patel, et al Lancet Respir Med Published:January 21, 2023 DOI:https://doi.org/10.1016/S2213-2600(22)00489-1 Summary Background Patients who have received mechanical ventilation can have prolonged cognitive impairment for which there is no known treatment. We aimed to...

ARTICLES|ONLINE FIRST Effect of non-invasive ventilation after extubation in critically ill patients with obesity in France: a multicentre, unblinded, pragmatic randomised clinical trial Audrey De Jong, Anne Bignon, François Stephan, et al. Lancet Respir Med Published:January 21, 2023 DOI:https://doi.org/10.1016/S2213-2600(22)00529-X Summary Background Non-invasive ventilation (NIV) and oxygen therapy (high-flow nasal oxygen [HFNO] or standard oxygen)...

ARTICLES|ONLINE FIRST Continued enteral nutrition until extubation compared with fasting before extubation in patients in the intensive care unit: an open-label, cluster-randomised, parallel-group, non-inferiority trial Mickaël Landais, Mai-Anh Nay, Johann Auchabie, et al. Lancet Respir Med Published:January 21, 2023 DOI:https://doi.org/10.1016/S2213-2600(22)00413-1 Summary Background Fasting is frequently imposed before extubation in patients in inte...