Original Investigation  January 3, 2023 Effect of Remifentanil vs Neuromuscular Blockers During Rapid Sequence Intubation on Successful Intubation Without Major Complications Among Patients at Risk of Aspiration: A Randomized Clinical Trial Nicolas Grillot, Gilles Lebuffe, Olivier Huet, et al JAMA. 2023;329(1):28-38. doi:10.1001/jama.2022.23550 Key Points Question  Are rapid-onset opioids noninferior to rapid-onset neuromuscular ...

Research Letter  November 18, 2022 COVID-19 and Excess All-Cause Mortality in the US and 20 Comparison Countries, June 2021-March 2022 Alyssa Bilinski, Kathryn Thompson, Ezekiel Emanuel JAMA. 2023;329(1):92-94. doi:10.1001/jama.2022.21795 The US experienced high COVID-19 death rates and higher excess all-cause mortality compared with peer countries during 2020.1 However, an important question is how cross-national differences in mortality shifted ...

Original Investigation  December 27, 2022 Association of Family Income With Morbidity and Mortality Among US Lower-Income Children and Adolescents Victoria Udalova, Vinayak Bhatia, Maria Polyakova JAMA. 2022;328(24):2422-2430. doi:10.1001/jama.2022.22778 Key Points Question  Among children and adolescents from lower-income families in the US, is family income associated with health? Findings  This cross-sectional stu...

BEST OF JAMA NETWORK Most Viewed Articles 2022 – JAMA Read the most popular JAMA articles in 2022 covering the ongoing COVID-19 pandemic, the latest US Preventive Services Task Force recommendations, management of acute coronary syndromes, and more. COVID-19 False-Positive Results in Rapid Antigen Tests for SARS-CoV-2JAMA Research LetterFebruary 1, 2022 Myocarditis Cases Reported After mRNA-Based COVID-19 Vaccination in the US From December 2020 to Au...

Medical News & Perspectives  December 27, 2022 JAMA Network Articles of the Year 2022 Melissa Suran JAMA. 2022;328(24):2381-2385. doi:10.1001/jama.2022.17761 For our sixth annual Articles of the Year roundup, we considered all Original Investigations, Special Communications, and Brief Reports published across the JAMA Network from October 1, 2021, through September 30, 2022, and ranked them based on online views. Editors from each journal...

ARTICLES|ONLINE FIRST The effect of higher protein dosing in critically ill patients with high nutritional risk (EFFORT Protein): an international, multicentre, pragmatic, registry-based randomised trial Daren K Heyland, Jayshil Patel, Charlene Compher, et al. Lancet Published:January 25, 2023 DOI:https://doi.org/10.1016/S0140-6736(22)02469-2 Summary Background On the basis of low-quality evidence, international critical care nutrition guidelines reco...

CRITICAL CARE: ORIGINAL RESEARCH| VOLUME 162, ISSUE 5, P1063-1073, NOVEMBER 01, 2022 Outcomes and Predictors of 28-Day Mortality in Patients With Solid Tumors and Septic Shock Defined by Third International Consensus Definitions for Sepsis and Septic Shock Criteria John A. Cuenca, Nirmala K. Manjappachar, Claudia M. Ramírez, et al Chest 2022; 162: 1063-1073 Published:May 26, 2022 DOI:https://doi.org/10.1016/j.chest.2022.05.017 Background D...

ORIGINAL ARTICLE Early Extracorporeal CPR for Refractory Out-of-Hospital Cardiac Arrest Martje M. Suverein, Thijs S.R. Delnoij, Roberto Lorusso, et al N Engl J Med 2023; 388:299-309DOI: 10.1056/NEJMoa2204511 Abstract BACKGROUND Extracorporeal cardiopulmonary resuscitation (CPR) restores perfusion and oxygenation in a patient who does not have spontaneous circulation. The evidence with regard to the effect of extracorporeal CPR on survival with a favorabl...

Research Retracted papers originating from paper mills: cross sectional study Cristina Candal-Pedreira, Joseph S Ross, Alberto Ruano-Ravina, et al BMJ 2022; 379 doi: https://doi.org/10.1136/bmj-2022-071517 (Published 28 November 2022)Cite this as: BMJ 2022;379:e071517 Abstract Objectives To describe retracted papers originating from paper mills, including their characteristics, visibility, and impact over time, and the journals in which they were publi...

ARTICLES|ONLINE FIRST Rituximab versus intravenous cyclophosphamide in patients with connective tissue disease-associated interstitial lung disease in the UK (RECITAL): a double-blind, double-dummy, randomised, controlled, phase 2b trial Toby M Maher, Veronica A Tudor, Peter Saunders, et al. Lancet Respir Med Published:November 11, 2022 DOI:https://doi.org/10.1016/S2213-2600(22)00359-9 Summary Background Rituximab is often used as rescue therapy in in...