Original Investigation  December 27, 2022 Association of Family Income With Morbidity and Mortality Among US Lower-Income Children and Adolescents Victoria Udalova, Vinayak Bhatia, Maria Polyakova JAMA. 2022;328(24):2422-2430. doi:10.1001/jama.2022.22778 Key Points Question  Among children and adolescents from lower-income families in the US, is family income associated with health? Findings  This cross-sectional stu...

BEST OF JAMA NETWORK Most Viewed Articles 2022 – JAMA Read the most popular JAMA articles in 2022 covering the ongoing COVID-19 pandemic, the latest US Preventive Services Task Force recommendations, management of acute coronary syndromes, and more. COVID-19 False-Positive Results in Rapid Antigen Tests for SARS-CoV-2JAMA Research LetterFebruary 1, 2022 Myocarditis Cases Reported After mRNA-Based COVID-19 Vaccination in the US From December 2020 to Au...

Medical News & Perspectives  December 27, 2022 JAMA Network Articles of the Year 2022 Melissa Suran JAMA. 2022;328(24):2381-2385. doi:10.1001/jama.2022.17761 For our sixth annual Articles of the Year roundup, we considered all Original Investigations, Special Communications, and Brief Reports published across the JAMA Network from October 1, 2021, through September 30, 2022, and ranked them based on online views. Editors from each journal...

ARTICLES|ONLINE FIRST The effect of higher protein dosing in critically ill patients with high nutritional risk (EFFORT Protein): an international, multicentre, pragmatic, registry-based randomised trial Daren K Heyland, Jayshil Patel, Charlene Compher, et al. Lancet Published:January 25, 2023 DOI:https://doi.org/10.1016/S0140-6736(22)02469-2 Summary Background On the basis of low-quality evidence, international critical care nutrition guidelines reco...

CRITICAL CARE: ORIGINAL RESEARCH| VOLUME 162, ISSUE 5, P1063-1073, NOVEMBER 01, 2022 Outcomes and Predictors of 28-Day Mortality in Patients With Solid Tumors and Septic Shock Defined by Third International Consensus Definitions for Sepsis and Septic Shock Criteria John A. Cuenca, Nirmala K. Manjappachar, Claudia M. Ramírez, et al Chest 2022; 162: 1063-1073 Published:May 26, 2022 DOI:https://doi.org/10.1016/j.chest.2022.05.017 Background D...

ORIGINAL ARTICLE Early Extracorporeal CPR for Refractory Out-of-Hospital Cardiac Arrest Martje M. Suverein, Thijs S.R. Delnoij, Roberto Lorusso, et al N Engl J Med 2023; 388:299-309DOI: 10.1056/NEJMoa2204511 Abstract BACKGROUND Extracorporeal cardiopulmonary resuscitation (CPR) restores perfusion and oxygenation in a patient who does not have spontaneous circulation. The evidence with regard to the effect of extracorporeal CPR on survival with a favorabl...

Research Retracted papers originating from paper mills: cross sectional study Cristina Candal-Pedreira, Joseph S Ross, Alberto Ruano-Ravina, et al BMJ 2022; 379 doi: https://doi.org/10.1136/bmj-2022-071517 (Published 28 November 2022)Cite this as: BMJ 2022;379:e071517 Abstract Objectives To describe retracted papers originating from paper mills, including their characteristics, visibility, and impact over time, and the journals in which they were publi...

ARTICLES|ONLINE FIRST Rituximab versus intravenous cyclophosphamide in patients with connective tissue disease-associated interstitial lung disease in the UK (RECITAL): a double-blind, double-dummy, randomised, controlled, phase 2b trial Toby M Maher, Veronica A Tudor, Peter Saunders, et al. Lancet Respir Med Published:November 11, 2022 DOI:https://doi.org/10.1016/S2213-2600(22)00359-9 Summary Background Rituximab is often used as rescue therapy in in...

Favipiravir for Treatment of Outpatients With Asymptomatic or Uncomplicated Coronavirus Disease 2019: A Double-Blind, Randomized, Placebo-Controlled, Phase 2 Trial  Marisa Holubar,  Aruna Subramanian,  Natasha Purington,  et al Clinical Infectious Diseases, Volume 75, Issue 11, 1 December 2022, Pages 1883–1892, https://doi.org/10.1093/cid/ciac312 Abstract Background Favipiravir, an oral, RNA-dependent RNA polymerase inhibitor, has in vitroactivity...

Research Changing patterns in reporting and sharing of review data in systematic reviews with meta-analysis of the effects of interventions: cross sectional meta-research study Phi-Yen Nguyen, Raju Kanukula, Joanne E McKenzie, et al BMJ 2022; 379 doi: https://doi.org/10.1136/bmj-2022-072428 (Published 22 November 2022)Cite this as: BMJ 2022;379:e072428 Abstract Objectives To examine changes in completeness of reporting and frequency of sharing data, an...