ORIGINAL ARTICLE Transplantation Outcomes with Donor Hearts after Circulatory Death Jacob N. Schroder, Chetan B. Patel, Adam D. DeVore, et al N Engl J Med 2023; 388:2121-2131DOI: 10.1056/NEJMoa2212438 Abstract BACKGROUND Data showing the efficacy and safety of the transplantation of hearts obtained from donors after circulatory death as compared with hearts obtained from donors after brain death are limited. METHODS We conducted a randomized, nonin...

Original Investigation  June 2, 2023 Direct Oral Anticoagulants vs Low-Molecular-Weight Heparin and Recurrent VTE in Patients With Cancer: A Randomized Clinical Trial Deborah Schrag, Hajime Uno, Rachel Rosovsky, et al JAMA. Published online June 2, 2023. doi:10.1001/jama.2023.7843 Key Points Question  Among patients with cancer and a venous thromboembolism (VTE) event, are direct oral anticoagulants noninferior to low-molecular-w...

ARTICLES|ONLINE FIRST Risk and accuracy of outpatient-identified hypoxaemia for death among suspected child pneumonia cases in rural Bangladesh: a multifacility prospective cohort study Eric D McCollum, Salahuddin Ahmed, Arunangshu D Roy, et al. Lancet Respir Med Open Access Published:April 07, 2023 DOI:https://doi.org/10.1016/S2213-2600(23)00098-X Summary Background Hypoxaemic pneumonia mortality risk in low-income and middle-income countries is high...

ARTICLES|ONLINE FIRST Extracorporeal cardiopulmonary resuscitation versus conventional cardiopulmonary resuscitation in adults with cardiac arrest: a comparative meta-analysis and trial sequential analysis Christopher Jer Wei Low, Kollengode Ramanathan, Ryan Ruiyang Ling, et al. Lancet Respir Med Published:May 22, 2023 DOI:https://doi.org/10.1016/S2213-2600(23)00137-6 Summary Background Although outcomes of patients after cardiac arrest remain poor, s...

ARTICLES|ONLINE FIRST Prospective evaluation of the efficacy, safety, and optimal biomarker enrichment strategy for nangibotide, a TREM-1 inhibitor, in patients with septic shock (ASTONISH): a double-blind, randomised, controlled, phase 2b trial Bruno François, Simon Lambden, Tom Fivez, et al. Lancet Respir Med Published:May 31, 2023 DOI:https://doi.org/10.1016/S2213-2600(23)00158-3 Summary Background Activation of the triggering receptor expressed on...

ARTICLES| VOLUME 11, ISSUE 6, P520-529, JUNE 2023 Outcome predictors and patient progress following delivery in pregnant and postpartum patients with severe COVID-19 pneumonitis in intensive care units in Israel (OB-COVICU): a nationwide cohort study Elena Fatnic, Nikole Lee Blanco, Roman Cobiletchi, et al. Lancet Respir Med 2023; 11: 520-529 DOI:https://doi.org/10.1016/S2213-2600(22)00491-X Summary Background A key unresolved controver...

ARTICLES| VOLUME 4, ISSUE 6, E431-E441, JUNE 2023 Effect of viral storm in patients admitted to intensive care units with severe COVID-19 in Spain: a multicentre, prospective, cohort study Jesús F Bermejo-Martin, Nadia García-Mateo, Anna Motos, et al. Lancet Microbe 2023; 4: E431-E441 DOI:https://doi.org/10.1016/S2666-5247(23)00041-1 Summary Background The contribution of the virus to the pathogenesis of severe COVID-19 is still unclear...

ARTICLES| VOLUME 4, ISSUE 6, E418-E430, JUNE 2023 Omicron BA.1-specific T-cell responses in adults vaccinated with CoronaVac or BNT162b2 in Hong Kong: an observational cohort study Chris Ka Pun Mok, Chunke Chen, Shilin Zhao, et al. Lancet Microbe 2023; 4: E418-E430 DOI:https://doi.org/10.1016/S2666-5247(23)00006-X Summary Background The primary aim of using vaccines in public health responses to SARS-CoV-2 variants of concern is to redu...

ARTICLES| VOLUME 4, ISSUE 6, E409-E417, JUNE 2023 SARS-CoV-2 incubation period across variants of concern, individual factors, and circumstances of infection in France: a case series analysis from the ComCor study Simon Galmiche, Thomas Cortier, Tiffany Charmet, et al. Lancet Microbe 2023; 6: E409-E417 DOI:https://doi.org/10.1016/S2666-5247(23)00005-8 Summary Background The incubation period of SARS-CoV-2 has been estimated for the know...

ARTICLES| VOLUME 4, ISSUE 6, E397-E408, JUNE 2023 Risk factors and vectors for SARS-CoV-2 household transmission: a prospective, longitudinal cohort study Nieves Derqui, Aleksandra Koycheva, Jie Zhou, et al Lancet Microbe 2023; 4: E397-E408 DOI:https://doi.org/10.1016/S2666-5247(23)00069-1 Summary Background Despite circumstantial evidence for aerosol and fomite spread of SARS-CoV-2, empirical data linking either pathway with transmissi...