ARTICLES|ONLINE FIRST Risk and accuracy of outpatient-identified hypoxaemia for death among suspected child pneumonia cases in rural Bangladesh: a multifacility prospective cohort study Eric D McCollum, Salahuddin Ahmed, Arunangshu D Roy, et al. Lancet Respir Med Open Access Published:April 07, 2023 DOI:https://doi.org/10.1016/S2213-2600(23)00098-X Summary Background Hypoxaemic pneumonia mortality risk in low-income and middle-income countries is high...

ARTICLES|ONLINE FIRST Extracorporeal cardiopulmonary resuscitation versus conventional cardiopulmonary resuscitation in adults with cardiac arrest: a comparative meta-analysis and trial sequential analysis Christopher Jer Wei Low, Kollengode Ramanathan, Ryan Ruiyang Ling, et al. Lancet Respir Med Published:May 22, 2023 DOI:https://doi.org/10.1016/S2213-2600(23)00137-6 Summary Background Although outcomes of patients after cardiac arrest remain poor, s...

ARTICLES|ONLINE FIRST Prospective evaluation of the efficacy, safety, and optimal biomarker enrichment strategy for nangibotide, a TREM-1 inhibitor, in patients with septic shock (ASTONISH): a double-blind, randomised, controlled, phase 2b trial Bruno François, Simon Lambden, Tom Fivez, et al. Lancet Respir Med Published:May 31, 2023 DOI:https://doi.org/10.1016/S2213-2600(23)00158-3 Summary Background Activation of the triggering receptor expressed on...

ARTICLES| VOLUME 11, ISSUE 6, P520-529, JUNE 2023 Outcome predictors and patient progress following delivery in pregnant and postpartum patients with severe COVID-19 pneumonitis in intensive care units in Israel (OB-COVICU): a nationwide cohort study Elena Fatnic, Nikole Lee Blanco, Roman Cobiletchi, et al. Lancet Respir Med 2023; 11: 520-529 DOI:https://doi.org/10.1016/S2213-2600(22)00491-X Summary Background A key unresolved controver...

ARTICLES| VOLUME 4, ISSUE 6, E431-E441, JUNE 2023 Effect of viral storm in patients admitted to intensive care units with severe COVID-19 in Spain: a multicentre, prospective, cohort study Jesús F Bermejo-Martin, Nadia García-Mateo, Anna Motos, et al. Lancet Microbe 2023; 4: E431-E441 DOI:https://doi.org/10.1016/S2666-5247(23)00041-1 Summary Background The contribution of the virus to the pathogenesis of severe COVID-19 is still unclear...

ARTICLES| VOLUME 4, ISSUE 6, E418-E430, JUNE 2023 Omicron BA.1-specific T-cell responses in adults vaccinated with CoronaVac or BNT162b2 in Hong Kong: an observational cohort study Chris Ka Pun Mok, Chunke Chen, Shilin Zhao, et al. Lancet Microbe 2023; 4: E418-E430 DOI:https://doi.org/10.1016/S2666-5247(23)00006-X Summary Background The primary aim of using vaccines in public health responses to SARS-CoV-2 variants of concern is to redu...

ARTICLES| VOLUME 4, ISSUE 6, E409-E417, JUNE 2023 SARS-CoV-2 incubation period across variants of concern, individual factors, and circumstances of infection in France: a case series analysis from the ComCor study Simon Galmiche, Thomas Cortier, Tiffany Charmet, et al. Lancet Microbe 2023; 6: E409-E417 DOI:https://doi.org/10.1016/S2666-5247(23)00005-8 Summary Background The incubation period of SARS-CoV-2 has been estimated for the know...

ARTICLES| VOLUME 4, ISSUE 6, E397-E408, JUNE 2023 Risk factors and vectors for SARS-CoV-2 household transmission: a prospective, longitudinal cohort study Nieves Derqui, Aleksandra Koycheva, Jie Zhou, et al Lancet Microbe 2023; 4: E397-E408 DOI:https://doi.org/10.1016/S2666-5247(23)00069-1 Summary Background Despite circumstantial evidence for aerosol and fomite spread of SARS-CoV-2, empirical data linking either pathway with transmissi...

Research Recovery and symptom trajectories up to two years after SARS-CoV-2 infection: population based, longitudinal cohort study Tala Ballouz, Dominik Menges, Alexia Anagnostopoulos, et al BMJ 2023; 381 doi: https://doi.org/10.1136/bmj-2022-074425 (Published 31 May 2023)Cite this as: BMJ 2023;381:e074425 Abstract Objective To evaluate longer term symptoms and health outcomes associated with post-covid-19 condition within a cohort of individuals with ...

Original Investigation  June 20, 2023 Evidence of Lack of Treatment Efficacy Derived From Statistically Nonsignificant Results of Randomized Clinical Trials Thomas Perneger, Angèle Gayet-Ageron JAMA. 2023;329(23):2050-2056. doi:10.1001/jama.2023.8549 Key Points Question  Can a statistically nonsignificant result of a randomized clinical trial provide conclusive evidence of lack of effect of the new treatment? Findings &nb...