Research Educational inequalities in mortality and their mediators among generations across four decades: nationwide, population based, prospective cohort study based on the ChinaHEART project Jiapeng Lu, Chaoqun Wu, Xiaoyan Zhang, et al BMJ 2023; 382 doi: https://doi.org/10.1136/bmj-2022-073749 (Published 19 July 2023)Cite this as: BMJ 2023;382:e073749 Abstract Objectives To assess the different educational inequalities in mortality among generations ...

Original Investigation  July 18, 2023 Accelerometer-Derived “Weekend Warrior” Physical Activity and Incident Cardiovascular Disease Shaan Khurshid, Mostafa A. Al-Alusi, Timothy W. Churchill, et al JAMA. 2023;330(3):247-252. doi:10.1001/jama.2023.10875 Key Points Question  Does engagement in moderate to vigorous physical activity, with most activity concentrated within 1 to 2 days of the week (ie, a “weekend warrior” pattern), con...

CHEST INFECTIONS: ORIGINAL RESEARCH| VOLUME 163, ISSUE 1, P77-88, JANUARY 2023Download Full Issue Machine-Learning Model for Mortality Prediction in Patients With Community-Acquired Pneumonia: Development and Validation Study Catia Cilloniz, Logan Ward, Mads Lause Mogensen, et al Chest 2023; 163: 77-88 Published:July 15, 2022 DOI:https://doi.org/10.1016/j.chest.2022.07.005 Background Artificial intelligence tools and techniques such as machine learning (...

Research Prevalence and predictors of data and code sharing in the medical and health sciences: systematic review with meta-analysis of individual participant data Daniel G Hamilton, Kyungwan Hong, Hannah Fraser, et al BMJ 2023; 382 doi: https://doi.org/10.1136/bmj-2023-075767 (Published 11 July 2023)Cite this as: BMJ 2023;382:e075767 Abstract Objectives To synthesise research investigating data and code sharing in medicine and health to establish an a...

ASTHMA: ORIGINAL RESEARCH| VOLUME 163, ISSUE 1, P38-51, JANUARY 2023 Extracorporeal Membrane Oxygenation for Refractory Asthma Exacerbations With Respiratory Failure Jonathan K. Zakrajsek, Sung-Joon Min, P. Michael Ho, et al Chest 2023; 163: 38-51 Published:September 29, 2022 DOI:https://doi.org/10.1016/j.chest.2022.09.029 Background Asthma exacerbations with respiratory failure (AERF) are associated with hospital mortality of 7% to 15%. Extracorpor...

CRITICAL CARE: ORIGINAL RESEARCH| VOLUME 163, ISSUE 1, P115-127, JANUARY 2023Download Full Issue A 30-Minute Spontaneous Breathing Trial Misses Many Children Who Go On to Fail a 120-Minute Spontaneous Breathing Trial Kelby E. Knox, Justin C. Hotz, Christopher J.L. Newth, et al Chest 2023; 163: 115-127 Published:August 26, 2022 DOI:https://doi.org/10.1016/j.chest.2022.08.2212 Background The optimal length of spontaneous breathing trials (SB...

CHEST INFECTIONS: ORIGINAL RESEARCH| VOLUME 163, ISSUE 1, P64-76, JANUARY 2023Download Full Issue A Double-Blind Randomized Placebo-Controlled Phase 3 Trial of Tobramycin Inhalation Solution in Adults With Bronchiectasis With Pseudomonas aeruginosa Infection Wei-jie Guan, Jin-fu Xu, Hong Luo, et al Chest 2023; 163: 64-67 Published:July 18, 2022 DOI:https://doi.org/10.1016/j.chest.2022.07.007 Background Few large-scale studies hav...

CRITICAL CARE: ORIGINAL RESEARCH| VOLUME 163, ISSUE 1, P128-138, JANUARY 2023Download Full Issue Temporal Trends and Variation in Bronchoscopy Use for Acute Respiratory Failure in the United States Max T. Wayne, Thomas S. Valley, Douglas A. Arenberg, et al Chest 2023; 163: 128-138 Published:August 22, 2022 DOI:https://doi.org/10.1016/j.chest.2022.08.2210 Background National data on bronchoscopy for the evaluation of acute respiratory failure are lacking,...

CRITICAL CARE: ORIGINAL RESEARCH| VOLUME 163, ISSUE 2, P303-312, FEBRUARY 2023Download Full Issue High-Dose IV Hydroxocobalamin (Vitamin B12) in Septic Shock: A Double-Blind, Allocation-Concealed, Placebo-Controlled Single-Center Pilot Randomized Controlled Trial (The Intravenous Hydroxocobalamin in Septic Shock Trial) Jayshil J. Patel, Rodney Willoughby, Jennifer Peterson, et al Chest 2023; 163: 303-312 Published:September 26, 2022 DOI:https://doi.org/10.1016...

CHEST INFECTIONS: ORIGINAL RESEARCH| VOLUME 163, ISSUE 3, P484-497, MARCH 2023Download Full Issue Effect of Corticosteroids on Mortality and Clinical Cure in Community-Acquired Pneumonia: A Systematic Review, Meta-analysis, and Meta-regression of Randomized Control Trials Naveed Saleem, Adarsh Kulkarni, Timothy Arthur Chandos Snow, et al Chest 2023; 163: 484-497 Published:September 07, 2022 DOI:https://doi.org/10.1016/j.chest.2022.08.2229 Background Comm...