Original Investigation  November 6, 2023 Overnight Stay in the Emergency Department and Mortality in Older Patients Melanie Roussel, Dorian Teissandier, Youri Yordanov, et al JAMA Intern Med. Published online November 6, 2023. doi:10.1001/jamainternmed.2023.5961 Key Points Question  Is spending a night in the emergency department (ED) associated with increased in-hospital mortality and morbidity...

Magnesium sulphate in patients with thrombotic thrombocytopenic purpura (MAGMAT): a randomised, double-blind, superiority trial Lara Zafrani, Emmanuel Canet, Anouk Walter-Petrich, et al Intensive Care Med 2023; 49: 1293-1304 Published: 23 October 2023 Abstract Purpose Studies have suggested benefits from magnesium sulphate in thrombotic thrombocytopenic purpura (TTP). We aimed to measure the effects of magnesium sulphate supplementation on TTP recovery. ...

ARTICLES| VOLUME 4, ISSUE 11, E883-E892, NOVEMBER 2023 Determinants of passive antibody efficacy in SARS-CoV-2 infection: a systematic review and meta-analysis Eva Stadler, Khai Li Chai, Timothy E Schlub, et al Lancet Microbe 2023; 4: E883-E892 Published:November, 2023 DOI:https://doi.org/10.1016/S2666-5247(23)00194-5 Summary Background Randomised controlled trials of passive antibodies as treatment and prophylaxis for COVID-19 have reported variable eff...

ARTICLES| VOLUME 4, ISSUE 11, E893-E902, NOVEMBER 2023Download Full Issue Transplacental transfer efficiency of maternal antibodies against influenza A(H1N1)pdm09 virus and dynamics of naturally acquired antibodies in Chinese children: a longitudinal, paired mother–neonate cohort study Mei Li, Wei Wang, Junbo Chen, et al Lancet Microbe 2023; 4: E893-E902 Published:October 09, 2023 DOI:https://doi.org/10.1016/S2666-5247(23)00181-7 Summary Back...

ARTICLES| VOLUME 4, ISSUE 11, E903-E912, NOVEMBER 2023 Severity of influenza-associated hospitalisations by influenza virus type and subtype in the USA, 2010–19: a repeated cross-sectional study Kelsey M Sumner, Svetlana Masalovich, Alissa O'Halloran, et al Lancet Microbe 2023; 4: E903-E912 Published: September 25, 2023 DOI:https://doi.org/10.1016/S2666-5247(23)00187-8 Summary Background Influenza burden varies across seasons, partly due to differences i...

ARTICLES| VOLUME 4, ISSUE 11, E931-E942, NOVEMBER 2023 Effect of amoxicillin on the gut microbiome of children with severe acute malnutrition in Madarounfa, Niger: a retrospective metagenomic analysis of a placebo-controlled trial Drew J Schwartz, Amy Langdon, Xiaoqing Sun, et al Lancet Microbe 2023; 4: E931-E942 Published:October 19, 2023 DOI:https://doi.org/10.1016/S2666-5247(23)00213-6 Summary Background Children with severe acute malnu...

Consciousness and Awareness in Cardiac Arrest Cardiac arrest (CA) is common in the United States, with a relatively low survival rate of around 10%. Understanding cognitive activity, consciousness, and awareness during CA and their impact on survivorship and psychological outcomes is of interest to organisations like the American Heart Association (AHA) but remains poorly understood. Some CA survivors report memory issues, depression, and post-traumatic stress d...

ARTICLES|ONLINE FIRST Effects of oral anticoagulation in people with atrial fibrillation after spontaneous intracranial haemorrhage (COCROACH): prospective, individual participant data meta-analysis of randomised trials Rustam Al-Shahi Salman, Jacqueline Stephen, Jayne F Tierney, et al. Lancet Neurol Open Access Published:October 12, 2023 DOI:https://doi.org/10.1016/S1474-4422(23)00315-0 Summary Background The safety and efficacy of oral anticoagulation ...

ARTICLES| VOLUME 22, ISSUE 11, P1005-1014, NOVEMBER 2023 Intracranial pressure monitoring with and without brain tissue oxygen pressure monitoring for severe traumatic brain injury in France (OXY-TC): an open-label, randomised controlled superiority trial Jean-François Payen, Yoann Launey, Russell Chabanne, et al Lancet Neurol 2023; 22: 1005-1014 Published: November, 2023 DOI:https://doi.org/10.1016/S1474-4422(23)00290-9 Summary Background Optimisatio...

Research Pharmaceutical industry payments and delivery of non-recommended and low value cancer drugs: population based cohort study Aaron P Mitchell, Stacie B Dusetzina, Akriti Mishra Meza, et al BMJ 2023; 383 doi: https://doi.org/10.1136/bmj-2023-075512 (Published 25 October 2023)Cite this as: BMJ 2023;383:e075512 Abstract Objective To estimate the association between oncologists’ receipt of payments from the pharmaceutical industry and delivery of no...