ESICM Guidelines on End-of-Life and Palliative Care In ICU Tue, 8 Oct 2024 End-of-life (EoL) care focuses on symptom relief and addressing the emotional, psychological, and spiritual needs of patients and their families. These decisions are influenced by ethical, legal, cultural, and resource-related factors, and practices vary globally. In some countries, life-supporting treatment (LST) decisions are shared with families, while in others, clinicians d...

Guidelines: Antibiotic Prophylaxis in Trauma In ICU Tue, 2 Apr 2024 Antibiotic prophylaxis (AP) in surgery prevents surgical site infections (SSIs). Despite clear recommendations from health authorities, AP is often misused globally, leading to reduced patient safety and increased antimicrobial resistance. Factors contributing to inappropriate AP use include errors in drug selection, dosage, duration, timing, and administration method.  In poly...

JAMA Clinical Guidelines Synopsis  June 20, 2024 Perioperative Management of Antithrombotic Therapy Maureen D. Lyons, Bailey Pope, Jason Alexander JAMA. Published online June 20, 2024. doi:10.1001/jama.2024.5880 Guideline title Perioperative Management of Antithrombotic Therapy: An American College of Chest Physicians Clinical Practice Guideline Release date November 2022 Developer and funding sou...

US Preventive Services Task Force  Recommendation Statement June 18, 2024 Interventions for High Body Mass Index in Children and Adolescents: US Preventive Services Task Force Recommendation Statement US Preventive Services Task Force JAMA. Published online June 18, 2024. doi:10.1001/jama.2024.11146 Abstract Importance  Approximately 19.7% of children and adolescents aged 2 to 19 years in the US have a body mass index (BM...

Consensus Statement  Pediatrics June 14, 2024 Clinical Practice Guideline for Red Blood Cell Transfusion Thresholds in Very Preterm Neonates Emöke Deschmann, Christof Dame, Martha C. Sola-Visner, et al JAMA Netw Open. 2024;7(6):e2417431. doi:10.1001/jamanetworkopen.2024.17431 Abstract Importance  Red blood cell (RBC) transfusion is a common medical intervention to treat anemia in very pret...

ESICM/NACCS Recommendations: Targeted Temperature Control Following TBI In ICU Wed, 22 May 2024 Traumatic brain injury (TBI) is a highly prevalent global health issue, causing significant mortality and disability. It results from external forces affecting brain function or structure. TBI involves primary damage from the initial impact, followed by secondary injury processes such as ischaemia, swelling, and metabolic changes, which worsen outc...

Corticosteroids in Critically Ill Patients With Sepsis, ARDS and CAP In ICU Tue, 14 May 2024 Critical illness-related corticosteroid insufficiency (CIRCI) is commonly seen in criticall ill patients and involves systemic inflammation, hypothalamus–pituitary–adrenal axis dysregulation, altered cortisol metabolism, and tissue glucocorticoid resistance. A task force of international experts from the Society of Critical Care Medicine (SCCM) and the ...

SOUNDING BOARD FROM THE NATIONAL ACADEMY OF MEDICINE Long Covid Defined E. Wesley Ely, Lisa M. Brown, Harvey V. Fineberg., for the National Academies of Sciences, Engineering, and Medicine Committee on Examining the Working Definition for Long Covid N Engl J Med Published July 31, 2024 DOI: 10.1056/NEJMsb2408466 The Covid-19 pandemic has been perceived mainly as a dangerous acute outbreak of infection that killed more ...

US Preventive Services Task Force  Recommendation Statement June 4, 2024 Interventions to Prevent Falls in Community-Dwelling Older Adults: US Preventive Services Task Force Recommendation Statement US Preventive Services Task Force JAMA. 2024;332(1):51-57. doi:10.1001/jama.2024.8481 Abstract Importance  Falls are the leading cause of injury-related morbidity and mortality among older adults in the US. In 2018, 27.5% of com...

Executive Summary: Guidelines on Use of Corticosteroids in Critically Ill Patients With Sepsis, Acute Respiratory Distress Syndrome, and Community-Acquired Pneumonia Focused Update 2024 Corticosteroids in Sepsis and Septic Shock Recommendation. 1A) We suggest administering corticosteroids to adult patients with septic shock (conditional recommendation, low certainty). 1B) We recommend against administration of high dose/short duration corticosteroids (defined ...