ICU Management & Practice, Volume 22 - Issue 5, 2022 Rapid Assessment of Fluid Responsiveness and Tolerance With Ultrasound of the Neck Vessels Ultrasonographic assessment of the neck vessels in critically ill patients contributes to rapid and non-invasive management of fluids to evaluate responsiveness and tolerance and blood volume status. Introduction There are multiple ways to evaluate the responsiveness and tolerance to IV fluids, as well as veno...

Editorial  March 21, 2023 Toward Personalizing Care: Assessing Heterogeneity of Treatment Effects in Randomized Trials Issa J. Dahabreh, Dhruv S. Kazi JAMA. 2023;329(13):1063-1065. doi:10.1001/jama.2023.3576 Clinicians know that individual patients may respond differently to a given treatment and that the overall treatment effect reported in a randomized trial of the treatment may not be directly applicable to all patients in clinical practice.1 D...

Strategies to Optimise Extubation Extubation failure refers to the inability to sustain spontaneous breathing after the removal of an artificial airway. The need for reintubation with 24 to 72 hours or up to seven days can lead to high morbidity, mortality and disability. The incidence of extubation failure in ICUs remains high (10-15%) and has two main causes: weaning failure and airway failure.  In this paper, the authors aim to update strategies for opti...

Viewpoint  March 23, 2023 Medical School Rankings—Bad for the Health of the Profession and the Public Holly J. Humphrey, Dana Levinson, Keme Carter JAMA. Published online March 23, 2023. doi:10.1001/jama.2023.2815 All of higher education sat up and took notice when Heather Gerken, dean of Yale Law School, announced in November 2022 that Yale would no longer contribute data to US News & World Report (USNWR) for the ranking of law...

Predicting Readmission, Death After Discharge From ICU Many machine learning (ML) models have been developed for use in the ICU, but their effectiveness in new settings is uncertain due to a lack of external validation. A study showed that less than one-third of Food and Drug Administration (FDA) approved ML models have undergone multisite assessment. In addition, only 11% of  ICU prediction models have been externally validated.  The ICU is a popular ...

Viewpoint  March 27, 2023 AI-Generated Medical Advice—GPT and Beyond Claudia E. Haupt, Mason Marks JAMA. Published online March 27, 2023. doi:10.1001/jama.2023.5321 For years, experts have speculated about the future role of artificial intelligence (AI) in health care. Some AI tools can outperform physicians on specific tasks in radiology, dermatology, and other fields, which raised concerns that AI might render certain specialists obsolete. ...

Effect of Higher Protein Dosing in Critically Ill Patients The international critical care nutrition guidelines recommend a wide range of protein doses that are based on low-quality evidence. The impact of high-dose protein in critically ill patients is unknown.  A study was conducted to test the hypothesis that a higher dose of protein improves clinical outcomes in critically ill patients. This was an international, registry-based, single-blinded, randomis...

Editorials Quality improvement in primary care Kath Checkland BMJ 2023; 380 doi: https://doi.org/10.1136/bmj.p582 (Published 22 March 2023)Cite this as: BMJ 2023;380:p582 Lessons from the end of QOF in Scotland The Quality and Outcomes Framework (QOF) pay-for-performance scheme began in the UK National Health Service in the early 2000s.1 Under a new contract, as much as 20% of general practices’ remuneration was initially tied to the achievement of per...

ICU Management & Practice, Volume 22 - Issue 5, 2022 Point of Care Ultrasound: The Critical Imaging Tool for the Critically Unwell This article aims to discuss the specific role of point of care ultrasound (POCUS) in the diagnosis and management of pathology in the critical care setting, as well as a specific tool to aid in invasive procedures. We discuss the ABCDE assessment of patients within critical care using POCUS. Introduction Since its introdu...

ICU Management & Practice, Volume 22 - Issue 5, 2022 The Role of Lung Imaging to Personalise Lung Ventilation in ARDS Patients Computed tomography (CT) remains an invaluable technique to evaluate lung morphology and response to ventilatory strategy and to understand the pathophysiology of Acute Respiratory Distress Syndrome (ARDS) patients. The first report of Acute Respiratory Distress Syndrome (ARDS) in 1967 described patients with severe hypoxaemia an...