Medium-Term and Long-Term Impact of COVID-19 As countries around the world become more accustomed to living with COVID-19, an important topic of discussion has been the medium-term and long-term impact of COVID-19 on respiratory function and health-related quality of life.  Most published studies on COVID-19 include patients with varying degrees of severity and evaluate patients up to six months after a COVID-19 episode. None of these studies specifically f...

EDITORIAL| VOLUME 161, ISSUE 2, P303-304, FEBRUARY 01, 2022 The Value of SEP-1 Richard Beale Chest 2022; 161: 303-304 Twenty years ago, the concept of sepsis as the host response to infection1 was still largely the obsession of intensivists and infectious diseases specialists. Deteriorating patients were recognized late,2 often presenting in a state of collapse, and the lack of a systematic approach to treatment resulted in variable clinical car...

ICU Management & Practice, Volume 22 - Issue 1, 2022 Coping With the Psychological Impact of Medical Errors: Some Practical Strategies Significant efforts have been made to make hospitals and ICUs as safe as possible. As healthcare workers (HCWs) try to get through this pandemic, the focus of this article is to explore practical steps to help these workers better cope with the psychological effects of being involved in an error event. Introduction: Error...

COMMENT|ONLINE FIRST The pandemic and the great awakening in the management of acute hypoxaemic respiratory failure Kiran Shekar, Ryan Ruiyang Ling Lancet Respir Med Published:March 16, 2022 DOI:https://doi.org/10.1016/S2213-2600(22)00051-0 The ability to provide invasive mechanical ventilation (IMV) and high-quality, supportive intensive care was substantially limited during the peak of the pandemic because of the unprecedented demand for intensive care un...

COMMENT| VOLUME 10, ISSUE 4, P319-320, APRIL 01, 2022 Bringing biological ARDS phenotypes to the bedside with machine-learning-based classifiers Stephen Whebell, J Zhang Lancet Respir Med Published:January 10, 2022 DOI:https://doi.org/10.1016/S2213-2600(21)00492-6 The identification of distinct phenotypes within heterogeneous disease states is a key component of personalised medicine, enabling enrichment of clinical trials, better prognostica...

#ISICEM22: HFNO Alone Versus HFNO Alternated With NIV (FLORALI-IM Study) Non-invasive ventilation (NIV) is recommended for immunocompromised patients with acute respiratory failure in the ICU. However, it can have harmful effects. High-flow nasal oxygen (HFNO) alone could be an alternative strategy to reduce mortality.  The HFNC Alone or Associated With NIV for Immunocompromised Patients Admitted to ICU for Acute Respiratory Failure (FLORALI-IM) study was conduc...

CORRESPONDENCE|ONLINE FIRST Shanghai's life-saving efforts against the current omicron wave of the COVID-19 pandemic Xinxin Zhang, Wenhong Zhang, Saijuan Chen Lancet Published:May 06, 2022 DOI: https://doi.org/10.1016/S0140-6736(22)00838-8 In late February, 2022, a wave of SARS-CoV-2 infection rapidly appeared in Shanghai, China. According to the Shanghai Municipal Health Commission, as of May 4, 2022, 601 942 cases have been identified, including 547 056 a...

ICU Management & Practice, Volume 22 - Issue 1, 2022 Diagnostic and Prognostic Value of Estimated Plasma Volume Status An overview of estimated plasma volume (ePVS), recent evidence supporting the association of ePVS with clinical congestion and whether it can help improve outcomes in patients with heart failure (HF). Plasma volume (PV) is the level of intravascular fluid minus the red blood cells, white blood cells and platelets. PV in heart failure (HF...

COMMENT| VOLUME 10, ISSUE 4, P314-315, APRIL 01, 2022 Baricitinib for patients with severe COVID-19—time to change the standard of care? Alexander Supady, Robert Zeiser Lancet Respir Med 2022; 10: 314-315 Mortality is high among patients with severe COVID-19 who require invasive mechanical ventilation (IMV) or extracorporeal membrane oxygenation (ECMO).1, 2 Therefore, further specific treatment options for these patients are urgently needed. ...

ICU Management & Practice, Volume 22 - Issue 1, 2022 Patient Safety in the ICU: Exploring Trends in Adverse Events in ICUs Adverse events (AEs) are common among critically ill patients. Evidence about the nature, preventability and predictability of AEs can be used to reinvest in efforts to reduce them and improve patient safety in ICUs. Case Mr. A, a previously well 70-year-old male was admitted to the intensive care unit (ICU) with respiratory failu...