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Recommended Reading from the NewYork-Presbyterian Hospital – Weill Cornell Medicine Pulmonary and Critical Care Medicine Fellows Kevin C. Ma, Daniel S. Jones, David R. Price, et al AJRCCM Articles in Press. Published on 13-March-2017 as 10.1164/rccm.201612-2478RR Neto AS, et al. Associations between ventilator settings during extracorporeal membrane oxygenation for refractory hypoxemia and outcome in patients with acute respiratory distress syndrome: a pooled individual pa...
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Recommended Reading from the NewYork-Presbyterian Hospital – Weill Cornell Medicine Pulmonary and Critical Care Medicine Fellows Kevin C. Ma, Daniel S. Jones, David R. Price, et al AJRCCM Articles in Press. Published on 13-March-2017 as 10.1164/rccm.201612-2478RR Dickson et al. Enrichment of the lung microbiome with gut bacteria in sepsis and the acute respiratory distress syndrome. Nat Microbio (8) Reviewed by Daniel S. Jones Acute respiratory distress syndrome (ARDS) is...
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Recommended Reading from the NewYork-Presbyterian Hospital – Weill Cornell Medicine Pulmonary and Critical Care Medicine Fellows Kevin C. Ma, Daniel S. Jones, David R. Price, et al AJRCCM Articles in Press. Published on 13-March-2017 as 10.1164/rccm.201612-2478RR Kor DJ. Effect of Aspirin on Development of ARDS in At-Risk Patients Presenting to the Emergency Department: The LIPS-A Randomized Clinical Trial. JAMA (1) Reviewed by Kevin C. Ma Acute respiratory distress syndr...
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Editorial March 21, 2017 Optimizing the Settings on the Ventilator Settings: High PEEP for All? Ary Serpa Neto, Marcus J. Schultz JAMA. Published online March 21, 2017. doi:10.1001/jama.2017.2570 Mechanical ventilation is an effective life-support technique widely deployed across a variety of clinical settings in the care of many millions of patients each year worldwide. However, it is not a panacea. A central issue is that artificial ventilation works by pushing air ...
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Medscape Critical Care > Critical Issues How to Interpret a Diffusion Capacity of the Lung for Carbon Monoxide Aaron B. Holley, MD March 07, 2017 Background The diffusion capacity of the lung for carbon monoxide (DLCO) is used to measure the body's ability to transfer oxygen across the alveolar-capillary membrane. [1] Internists use this test to identify interstitial lung disease, oncologists order it to assess the effects of chemotherapy, and pulmonologists use it f...
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EPIDEMIOLOGY OF ACUTE KIDNEY INJURY IN CRITICALLY ILL CHILDREN AND YOUNG ADULTS. Authors: Kaddourah A, Basu RK, Bagshaw SM, Goldstein SL for the AWARE Investigators. Reference: N Engl J Med, 2017; 376: 11-20 © Massachusetts Medical Society. Level of evidence: 4 ICM ABSTRACT Objective To define the incremental risk of death and complications associated with severe acute kidney injury (AKI) in critically ill children and young adults. Introduction In adult patients, AKI is ...
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近期,新英格兰医学杂志在线发表了ProCESS研究的结果。 这是一项多中心开放临床试验,旨在验证感染性休克患者采用6小时的EGDT复苏治疗策略能否改善临床预后。研究除EGDT组与常规治疗组外,还根据既往研究结果设置了简单治疗方案组。总共1341名感染性休克参加本项研究,并未发现三组患者间60天病死率存在显著差异。 对于这一令人沮丧的结果,相信有同事会提出以下的问题:那么,究竟应当如何治疗感染性休克呢? 首先,我们仍然相信,临床治疗需要高度个体化。不能简单将某一个(系列)固定的治疗目标(如CVP 8 - 12...
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如何避免被医学文献所误导?已关闭评论
中国医学科学院北京协和医学院 北京协和医院  翁利,杜斌 中华医学杂志2010; 49(10): 828-831 临床医生常常对浩如烟海的医学文献感到困扰。PubMed总共收录全世界70多个国家和地区的4000余种生物医学期刊,每周增加的文摘条目即超过10000条。遗憾的是,很多文献得到相互矛盾的结果。例如,严重全身性感染治疗指南依据循证医学(EBM)原则,总结了过去十年间的临床研究结果,就多项治疗措施予以推荐,如早期目标指导治疗(EGDT)、强化胰岛素治疗、肺保护性通气策略、应激剂量皮质激素治疗感染性休克、活化蛋白C、肾脏替...
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