Targeted Normoxaemia and Supplemental Oxygen–Free Days In ICU Tue, 8 Apr 2025 Critically ill patients often receive supplemental oxygen to prevent hypoxaemia, but excessive oxygen can lead to harmful effects like oxidative damage and inflammation. While higher oxygen levels may provide a safety margin, they also increase the risk of hyperoxaemia, particularly in resource-limited settings. Recent trials in ICU patients without trauma found no mortali...

Adjuvant Therapies for Haemorrhagic Shock In ICU Tue, 8 Apr 2025 Severe traumatic injuries cause 4.4 million deaths globally each year, with haemorrhage responsible for 35–40% of these deaths, making it the second leading cause after brain injuries. Haemorrhagic deaths occur rapidly, often before hospital arrival, necessitating fast, pre-hospital interventions like haemostatic dressings, tourniquets, hypothermia control, tranexamic acid, calcium manage...

Rationale for Early Arginine-Vasopressin Administration  In ICU Thu, 27 Mar 2025 The basics of vasopressor support and advanced considerations regarding its early use in intensive care settings. Introduction The use of vasopressors in critical care is a crucial aspect of haemodynamic management. While norepinephrine remains the primary agent of choice, the role of other vasopressors such as vasopressin has gained increasing attention. This discu...

Invited Commentary  May 28, 2025 Association of Familiarity of the Surgeon-Anesthesiologist Dyad With Major Morbidity After Surgery Jasmine Hwang, Rachel R. Kelz JAMA Surg. Published online May 28, 2025. doi:10.1001/jamasurg.2025.1376 We know patients do better when cared for by high-performing teams. Enhanced communication, trust, and experience contribute to the success of effective teams. These attributes are easier to achieve among teamma...

European Sepsis Care Survey: Sepsis Care in European Hospitals In Sepsis Thu, 3 Apr 2025 Sepsis remains a major global health issue, with nearly 49 million cases and 11 million deaths annually. International guidelines emphasise routine screening and standardised treatment protocols for high-risk patients. The World Health Assembly’s 2017 Resolution 70.7 and the G7 Health Ministers’ 2022 statement have called for enhanced prevention, diagnosis, and man...

Invited Commentary  Nephrology May 27, 2025 Corticosteroids—A Not-So-Novel Treatment for Sepsis-Associated AKI Sarah F. Sanghavi JAMA Netw Open. 2025;8(5):e2512286. doi:10.1001/jamanetworkopen.2025.12286 Sepsis is a multisystem disorder in which infection triggers a dysregulated host response consisting of concurrent hyperinflammation and immune suppression. Acute kidney injury (AKI) is a frequent manifestation of sepsis-induced circulator...

Wealth and Mortality in the United States and Europe In ICU Thu, 3 Apr 2025 A new study published in the New England Journal of Medicine reveals that Americans across all wealth levels face higher mortality rates than their European counterparts over a 10-year period. The research, led by experts at Brown University’s School of Public Health, compared data from more than 73,000 adults aged 50 to 85 in the U.S. and various regions of Europe. ...

Burnout Among Mexican Doctors: Perspective of Data from a Population Cohort In ICU Mon, 10 Mar 2025 ICU Management & Practice, Volume 25 - Issue 1, 2025 Our line of research is based on the problem of burnout syndrome in a hospital in Southeastern Mexico, analysing the impact of competence assessment and mistreatment in the workplace.          Introduction Burnout syndrome, first described by Maslac...

Editorials Post-traumatic stress disorder in intensive care survivors Natalia Wege, Mary Princip BMJ 2025; 389 doi: https://doi.org/10.1136/bmj.r841 (Published 07 May 2025)Cite this as: BMJ 2025;389:r841 A role for primary care Advances in intensive care medicine have improved survival rates, yet post-traumatic stress disorder (PTSD) remains a prevalent and often underdiagnosed consequence among patients who are discharged from intensive care units.1 A...

Causes and Consequences of Physician Burnout and the Importance of Well-Being In ICU Mon, 10 Mar 2025 ICU Management & Practice, Volume 25 - Issue 1, 2025 Physician burnout has emerged as a critical issue in healthcare over the past few years, with significant implications for the entire system. This multifaceted problem stems from a combination of individual factors and systemic concerns. By addressing this issue comprehensively, healthcare sy...