AKI: long-term impact on mortality and renal function Acute kidney injury (AKI) is defined as an abrupt loss in renal function and may be caused by a wide variety of clinical conditions. AKI is a frequent complication of hospitalisation and is associated with an increased risk of chronic kidney disease (CKD), end-stage renal disease (ESRD), and mortality.Based on more recent studies, AKI is also known to be a risk factor for other adverse outcomes, including stroke...

Editorial|February 17, 2019 How Best to Resuscitate Patients With Septic Shock? Derek C. Angus JAMA. 2019;321(7):647-648. doi:10.1001/jama.2019.0070 What is the best approach for resuscitation of a patient with septic shock? Despite considerable investigation over several decades, this important question still has no clear answer. There is agreement that resuscitation should proceed quickly, for the longer the delay, the greater the physiologic ...