Original Investigation  January 27, 2025 Negative Pressure Dressings to Prevent Surgical Site Infection After Emergency Laparotomy: The SUNRRISE Randomized Clinical Trial SUNRRISE Trial Study Group JAMA. Published online January 27, 2025. doi:10.1001/jama.2024.24764 Key Points Question  Among patients undergoing emergency laparotomy, is there a difference in surgical site infection (SSI) rates when the wound is treated with ...

Tracheostomy Management: From Intensive Care to Community In ICU Thu, 28 Nov 2024 ICU Management & Practice, Volume 24 - Issue 5, 2024 Tracheostomies are widely performed for a variety of reasons in the ICU. This article outlines the process of transitioning from critical care to the community with proactive management by a multidisciplinary team to wean patients from the ventilator and from the tracheostomy.  Introduction Approximat...

Invited Commentary  January 15, 2025 Turning Stress Into Success—Surgery as Professional Sport Steven Yule, Jennifer Yule, Calum Arthur JAMA Surg. Published online January 15, 2025. doi:10.1001/jamasurg.2024.6041 In the latest issue of JAMA Surgery, Awtry et al1 report that elevated surgeon stress, measured by heart rate variability (HRV) within the first 5 minutes of operating, is inversely associated ...

Original Investigation  Diabetes and Endocrinology January 21, 2025 Use of Albumin-Adjusted Calcium Measurements in Clinical Practice Noémie Desgagnés, James A. King, Gregory A. Kline, et al JAMA Netw Open. 2025;8(1):e2455251. doi:10.1001/jamanetworkopen.2024.55251 Key Points Question  How accurate are the calcium adjustment formulas that are used in clinical practice? Findings  ...

Editorial  March 18, 2025 Sevoflurane Sedation in Acute Respiratory Distress Syndrome: Time to Put It to Sleep Balasubramanian Venkatesh, Naomi Hammond, Anthony Delaney JAMA. Published online March 18, 2025. doi:10.1001/jama.2025.3023 Acute respiratory distress syndrome (ARDS) is characterized by hypoxemic respiratory failure and inflammatory injury to the lungs, and occurs in 10% of all intensive care unit admissions. ARDS accounts for nearl...

Original Investigation  January 15, 2025 Association Between Surgeon Stress and Major Surgical Complications Jake Awtry, Sarah Skinner, Stephanie Polazzi, et al JAMA Surg. Published online January 15, 2025. doi:10.1001/jamasurg.2024.6072 Key Points Question  Is surgeon physiological stress, as deduced from the sympathovagal balance measured via heart rate variability analysis, associated with pa...

Research Letter  January 2, 2025 Knowledge and Worry Following Review of Standard vs Patient-Centered Pathology Reports Cathryn J. Lapedis, Sophia R. Kurnot, Sarah E. Bergholtz, et al JAMA. Published online January 2, 2025. doi:10.1001/jama.2024.25461 The immediate release of test results to patients via patient portals is required.1,2 Unfortunately, pathology reports contain complex medical terminology...

Original Investigation  Caring for the Critically Ill Patient March 18, 2025 Optimal Vasopressin Initiation in Septic Shock: The OVISS Reinforcement Learning Study Alexandre Kalimouttou, Jason N. Kennedy, Jean Feng, et al JAMA. Published online March 18, 2025. doi:10.1001/jama.2025.3046 Key Points Question  Does a reinforcement learning model identify the optimal initiation rule for vasopress...

Original Investigation  Caring for the Critically Ill Patient March 18, 2025 Inhaled Sedation in Acute Respiratory Distress Syndrome: The SESAR Randomized Clinical Trial Matthieu Jabaudon, Jean-Pierre Quenot, Julio Badie, et al JAMA. Published online March 18, 2025. doi:10.1001/jama.2025.3169 Key Points Question  Is a strategy of inhaled sedation with sevoflurane safe and associated with improved clinical outcomes in patients ...

Editor's Note  January 13, 2025 The Limited Role for Antiviral Therapy in Influenza Jonathan D. Baghdadi, Deborah Grady, Daniel J. Morgan JAMA Intern Med. Published online January 13, 2025. doi:10.1001/jamainternmed.2024.7258 Influenza is associated with substantial morbidity and mortality. Given this, antiviral therapy is commonly prescribed in an effort to prevent these outcomes. We therefore found it surprising that antivirals seem to make...