Original Investigation  Geriatrics May 30, 2025 Parental Education, Own Education, and Cognitive Function in Middle-Aged and Older Adults Shengyu Luo, Weiqing Chen, Wanting Hu, et al JAMA Netw Open. 2025;8(5):e2513036. doi:10.1001/jamanetworkopen.2025.13036 Key Points Question  Are maternal and paternal education associated with cognitive declines in middle-aged and older adults, and do individuals’ own education mediate these...

European Sepsis Care Survey: Sepsis Care in European Hospitals In Sepsis Thu, 3 Apr 2025 Sepsis remains a major global health issue, with nearly 49 million cases and 11 million deaths annually. International guidelines emphasise routine screening and standardised treatment protocols for high-risk patients. The World Health Assembly’s 2017 Resolution 70.7 and the G7 Health Ministers’ 2022 statement have called for enhanced prevention, diagnosis, and man...

Special Communication  May 29, 2025 Platelet Transfusion2025 AABB and ICTMG International Clinical Practice Guidelines Ryan A. Metcalf, Susan Nahirniak, Gordon Guyatt, et al JAMA. Published online May 29, 2025. doi:10.1001/jama.2025.7529 Abstract Importance  Platelet transfusion is a frequent procedure with benefits and risks. Objective  To provide recommendations in adult and pedia...

Original Investigation  May 28, 2025 Hospital Ownership and Surgical Outcomes in East, Central, and Southern Africa Robert K. Parker, Yves Yankunze, Andrea S. Parker, et al JAMA Surg. Published online May 28, 2025. doi:10.1001/jamasurg.2025.1430 Key Points Question  Is hospital ownership type associated with surgical mortality rates in East, Central, and Southern Africa? Findings  I...

Invited Commentary  Nephrology May 27, 2025 Corticosteroids—A Not-So-Novel Treatment for Sepsis-Associated AKI Sarah F. Sanghavi JAMA Netw Open. 2025;8(5):e2512286. doi:10.1001/jamanetworkopen.2025.12286 Sepsis is a multisystem disorder in which infection triggers a dysregulated host response consisting of concurrent hyperinflammation and immune suppression. Acute kidney injury (AKI) is a frequent manifestation of sepsis-induced circulator...

Original Investigation  May 28, 2025 Familiarity of the Surgeon-Anesthesiologist Dyad and Major Morbidity After High-Risk Elective Surgery Julie Hallet, Angela Jerath, Pablo Perez d’Empaire, et al JAMA Surg. Published online May 28, 2025. doi:10.1001/jamasurg.2025.1386 Key Points Question  Is familiarity of the surgeon-anesthesiologist dyad associated with 90-day major morbidity after high-risk ...

Wealth and Mortality in the United States and Europe In ICU Thu, 3 Apr 2025 A new study published in the New England Journal of Medicine reveals that Americans across all wealth levels face higher mortality rates than their European counterparts over a 10-year period. The research, led by experts at Brown University’s School of Public Health, compared data from more than 73,000 adults aged 50 to 85 in the U.S. and various regions of Europe. ...

Research Letter  Equity, Diversity, and Inclusion May 28, 2025 Medical School Ranking and Neighborhood Characteristics of Initial Practice Location Among Physicians Navapat Nananukul, Mayank Kejriwal JAMA Netw Open. 2025;8(5):e2512474. doi:10.1001/jamanetworkopen.2025.12474 Introduction The US has experienced a chronic shortage of physicians in certain geographic regions, especially those that may be deprived.1 ...

Original Investigation  Emergency Medicine May 20, 2025 Preoxygenation With and Without Positive End-Expiratory Pressure in Lung-Healthy Volunteers: A Randomized Clinical Trial Giulia Roveri, Anna Camporesi, Alex Hofer, et al JAMA Netw Open. 2025;8(5):e2511569. doi:10.1001/jamanetworkopen.2025.11569 Key Points Question  Is there a difference in the efficacy of 3 preoxygenation devices for use...

Burnout Among Mexican Doctors: Perspective of Data from a Population Cohort In ICU Mon, 10 Mar 2025 ICU Management & Practice, Volume 25 - Issue 1, 2025 Our line of research is based on the problem of burnout syndrome in a hospital in Southeastern Mexico, analysing the impact of competence assessment and mistreatment in the workplace.          Introduction Burnout syndrome, first described by Maslac...