Original Investigation  Emergency Medical Individual Clinician Volume and Mortality in Trauma Patients Jamison Beiriger, Christian Martin-Gill, David S. Silver, et al JAMA Surg Published Online: February 18, 2026 doi: 10.1001/jamasurg.2025.6741 Key Points Question  Is the patient volume of individual emergency medical services (EMS) clinicians associated with trauma patient outcomes? Findings...

Research Letter  Pediatrics Clinical Decision Support for Antibiotic Prescribing Duration in Children With Acute Otitis Media Matt Mason, Sara Ruth Slovin, Arezoo Zomorrodi, et al JAMA Netw Open 2026;9;(2):e2560066. doi:10.1001/jamanetworkopen.2025.60066 Introduction Acute otitis media (AOM) is the most common indication for antibiotics in children.1 The American Academy of Pediatrics recommends 10 days of the...

Original Investigation  Nutrition, Obesity, and Exercise Leisure-Time Physical Activity and Cancer Mortality Among Cancer Survivors Erika Rees-Punia, Lauren R. Teras, Christina C. Newton, et al JAMA Netw Open 2026;9;(2):e2556971. doi:10.1001/jamanetworkopen.2025.56971 Key Points Question  Is engagement in physical activity after a cancer diagnosis associated with longer survival among individuals with a h...

Predictive Modelling for Respiratory Support With LLM-Driven Guideline In ICU Wed, 19 Nov 2025 A research study from the University of California, San Diego, describes an innovative approach to improving respiratory support decisions in intensive care units by integrating a large language model with an existing deep learning system. The work addresses a critical clinical challenge: determining whether patients at high risk of requiring invasive mechanical ...

Original Investigation  Anesthesiology Guideline Adherence of Perioperative Antibiotics and Surgical Site Infections in Noncardiac Surgery Amit Bardia, MBBS, Hung-Mo Lin, Xiwen Zhao, et al JAMA Netw Open 2026;9;(2):e2559349. doi:10.1001/jamanetworkopen.2025.59349 Key Points Question  What is the association of adherence to Infectious Diseases Society of America (IDSA) perioperative antibiotic prophylaxis ...

ONLINE FIRST (FREE ACCESS) PERIOPERATIVE CARE IN THE ICU What's New in Intensive Care The perioperative brain: navigating neurological risks in non-neurosurgical patientsBadenes, R., Romero-Garcia, N. & Marshall, T.J. PHYSIOLOGY IN CRITICAL ILLNESS Understanding the Disease Physiological effects of prone positioning during invasive mechanical ventilation: beyond PaO2Cornejo, R., Papazian, L. & Martin Delgado, M.C. LATEST ARTICLES Original ...

Original Investigation  Infectious Diseases Chlorhexidine vs Povidone-Iodine and Incidence of Catheter-Related Infections: A Systematic Review and Meta-Analysis Bertrand Drugeon, Gabor Mihala, Jessica Schults, et al JAMA Netw Open 2026;9;(2):e2558954. doi:10.1001/jamanetworkopen.2025.58954 Key Points Question  What concentration and formulation of chlorhexidine or povidone-iodine is associated with the lo...

Liberal or Restrictive Postoperative Transfusion in High-Risk Patients  In ICU Tue, 11 Nov 2025 Postoperative anaemia frequently occurs after major vascular or general surgical procedures and has been linked to an increased risk of short-term complications, especially in patients with pre-existing cardiovascular disease. While restrictive transfusion thresholds (haemoglobin < 7 g/dL) are generally considered safe for most hospitalised patients,...

Research Letter  Pediatrics Availability of Higher-Level Neonatal Care in Rural and Urban US Hospitals, 2010-2022 Katy B. Kozhimannil, Emily C. Sheffield, Clara E. Busse, et al JAMA Netw Open 2026;9;(2):e2559680. doi:10.1001/jamanetworkopen.2025.59680 Introduction Infant mortality is elevated for residents of rural US communities, in which access to childbirth care has been declining.1,2 Infants with high-acuity cl...

Persistent Opioid Use Among ICU Survivors After Discharge In ICU Tue, 11 Nov 2025 A recent study investigated the long-term continuation of opioid therapy among previously opioid-naïve patients following ICU treatment. Using a retrospective, nationwide cohort drawn from South Korea’s National Health Insurance Service (NHIS) database, the authors aimed to estimate the six-month incidence of new persistent opioid use and identify associated demographic, ...