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[JAMA发表论文]:改进肺炎患者抗生素选择的管理提示已关闭评论
Original Investigation  April 19, 2024 Stewardship Prompts to Improve Antibiotic Selection for Pneumonia: The INSPIRE Randomized Clinical Trial Shruti K. Gohil, Edward Septimus, Ken Kleinman, et al JAMA. Published online April 19, 2024. doi:10.1001/jama.2024.6248 Key Points Question  Can computerized provider order entry (CPOE) prompts that provide patient-specific risk estimates for multidrug-resistant organisms (MDROs) reduce e...
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[ICU Management & Practice]: 氨甲环酸治疗肝硬化患者急性上消化道出血已关闭评论
Tranexamic Acid for Acute UGIB in Patients With Cirrhosis In ICU Tue, 12 Mar 2024 A recent study aimed to assess the effectiveness and safety of tranexamic acid in treating acute upper gastrointestinal bleeding (UGIB) in patients with cirrhosis, particularly those classified as Child-Turcotte-Pugh (CTP) class B and C. These patients experience systemic and localised fibrinolysis in the mucosa of the oesophagus and stomach. The study included 600 pat...
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[JAMA Netw Open发表论文]:2015年至2021年间急诊科头痛诊断检查的变化已关闭评论
Original Investigation  Emergency Medicine April 19, 2024 Shifts in Diagnostic Testing for Headache in the Emergency Department, 2015 to 2021 Dustin G. Mark, Brandon H. Horton, Mary E. Reed, et al JAMA Netw Open. 2024;7(4):e247373. doi:10.1001/jamanetworkopen.2024.7373 Key Points Question  Has the diagnostic evaluation of headache in the emergency department recently changed? Findings  In a cohort study of 21 emer...
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[Lancet Infect Dis发表论文]:肠杆菌科细菌血流感染时从抗假单胞β-内酰胺抗生素进行结构性降阶梯治疗的效果与安全性已关闭评论
ARTICLES| VOLUME 24, ISSUE 4, P375-385, APRIL 2024 Efficacy and safety of a structured de-escalation from antipseudomonal β-lactams in bloodstream infections due to Enterobacterales (SIMPLIFY): an open-label, multicentre, randomised trial Luis Eduardo López-Cortés, Mercedes Delgado-Valverde, Elisa Moreno-Mellado, et al Lancet Infect Dis 2024; 24: 375-385 DOI:https://doi.org/10.1016/S1473-3099(23)00686-2 Summary Background De-escalation from broad-spec...
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[ICU Management & Practice]: 革兰阴性杆菌血流感染的多学科诊疗已关闭评论
Multidisciplinary Management of Gram-Negative Bloodstream Infections In ICU Tue, 12 Mar 2024 Bloodstream infections (BSIs) caused by Gram-negative pathogens pose significant challenges in ICU patients due to their high prevalence and severity, with mortality rates reported as high as 40%. The widespread prevalence of multidrug-resistant organisms (MDRO) further complicates antibiotic treatment choices, with mortality rates reaching 43% when MDROs are i...
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[BMJ发表论文]:胰高血糖素样肽-1受体激动剂的使用与甲状腺癌的风险已关闭评论
Research Glucagon-like peptide 1 receptor agonist use and risk of thyroid cancer: Scandinavian cohort study Björn Pasternak, Viktor Wintzell, Anders Hviid, et al BMJ 2024; 385 doi: https://doi.org/10.1136/bmj-2023-078225 (Published 10 April 2024)Cite this as: BMJ 2024;385:e078225 Abstract Objective To investigate whether use of glucagon-like peptide 1 (GLP1) receptor agonists is associated with increased risk of thyroid cancer. Design Scandinav...
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[NEJM发表论文]:救护车中针对超急性卒中患者实施强化降压措施已关闭评论
ORIGINAL ARTICLE Intensive Ambulance-Delivered Blood-Pressure Reduction in Hyperacute Stroke Gang Li, Yapeng Lin, Jie Yang, et al N Engl J Med 2024;390:1862-1872 DOI: 10.1056/NEJMoa2314741 Abstract BACKGROUND Treatment of acute stroke, before a distinction can be made between ischemic and hemorrhagic types, is challenging. Whether very early blood-pressure control in the ambulance improves outcomes among patients with undifferentiated acute stroke is ...
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[JAMA Netw Open发表论文]:急诊科护士不向医生推荐自己医院作为工作理想场所的原因已关闭评论
Original Investigation  Emergency Medicine April 9, 2024 Emergency Nurses’ Reasons for Not Recommending Their Hospital to Clinicians as a Good Place to Work K. Jane Muir, Raina M. Merchant, Karen B. Lasater, et al JAMA Netw Open. 2024;7(4):e244087. doi:10.1001/jamanetworkopen.2024.4087 Key Points Question  Why do emergency nurses not recommend their hospital to clinicians as a good place to work? Findings  This qu...
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[ICU Management & Practice]: 评估呼吸肌肉预测脱机结局已关闭评论
Respiratory Muscle Assessments to Predict Weaning Outcomes In ICU Tue, 12 Mar 2024 Various factors influence failure to wean from mechanical ventilation, including respiratory muscle dysfunction, which is strongly associated with weaning failure and mortality. However, respiratory muscle function assessment is not routinely performed in most ICUs.  Various bedside tools are available for assessing respiratory muscle function, including non-voli...
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[JAMA Surg发表论文]:CT自动分析人体成分作为腹部手术衰弱的生物标志物已关闭评论
Original Investigation  April 10, 2024 Automated CT Analysis of Body Composition as a Frailty Biomarker in Abdominal Surgery Ijeamaka Anyene Fumagalli, Sidney T. Le, Peter D. Peng, et al JAMA Surg. Published online April 10, 2024. doi:10.1001/jamasurg.2024.0628 Key Points Question  Can preoperative computed tomography (CT) scans provide patient frailty assessments that are associated with outcomes of abdominal surgery? Finding...
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