Original Investigation  Postoperative Pulmonary Complications in Conventional Laparoscopic vs Robot-Assisted Abdominal Surgery Simon Corrado Serafini, Sabrine N. T. Hemmes, Verônica N. F. Queiroz, et al JAMA Surg 2025;160;(11):1222-1231 doi:10.1001/jamasurg.2025.3581 Key Points Question  Is robotic-assisted surgery independently associated with higher incidence of postoperative pulmonary complications as compa...

Predicting Patient Deterioration with AI  In ICU Mon, 18 Aug 2025 Accurate recognition of patient deterioration has long been a cornerstone of safe and effective hospital care. The structured recording of vital signs dates back to the 19th century and was strengthened by the introduction of the National Early Warning Score (NEWS) in the United Kingdom in 2012, later updated to NEWS2 in 2017. This scoring system standardised responses to acute illn...

Original Investigation  Acute Normovolemic Hemodilution in Adult Cardiac Surgery Kenichi A. Tanaka, Kenneth E. Stewart, Kofi B. Vandyck, et al JAMA Surg 2025;160;(11):1195-1201. doi:10.1001/jamasurg.2025.3238 Key Points Question  What are the current practice patterns of acute normovolemic hemodilution (ANH) use in adult cardiac surgery? Findings  In this cohort study of 16 795 patients who underw...

Articles Global antibiotic consumption and regional antimicrobial resistance, 2010–21: an analysis of pharmaceutical sales and antimicrobial resistance surveillance data Ligui Wang, Hui Chen, Yuanyuan Zhang, et al Lancet Global Health 2025; 13: e1880-e1891 https://doi.org/10.1016/S2214-109X(25)00308-0 Summary Background The rising prevalence of antimicrobial resistance driven by inappropriate antibiotic consumption has become a major global challenge....

Original Investigation  Public Health Neighborhood Opportunity, Hospital Volume, and Pediatric Postoperative Mortality Sandra Tay, Christian Mpody, Joseph D. Tobias, et al JAMA Netw Open 2025;8;(11):e2543017. doi:10.1001/jamanetworkopen.2025.43017 Key Points Question  Are neighborhood opportunity and hospital volume associated with risk of postoperative mortality among pediatric patients? Findings ...

Personalised Temperature Management Post-Cardiac Arrest In ICU Wed, 20 Aug 2025 Out-of-hospital cardiac arrest (OHCA) affects over 300,000 people annually and remains a major public health issue. Survival and recovery after cardiac arrest (CA) largely depend on restoring circulation and minimising brain injury from ischaemia and reperfusion following return of spontaneous circulation (ROSC). Early trials showed benefits of therapeutic hypothermia (TH) ...

Original Investigation  International Reference Values for Surgical Outcomes of Total Pancreatectomy Philip C. Müller, Caroline Berchtold, Christoph Kuemmerli, et al JAMA Surg Published Online: November 12, 2025 doi: 10.1001/jamasurg.2025.4941 Key Points Question  What are international reference values for total pancreatectomy based on a low-risk cohort treated at expert centers? Findings&nb...

Original Investigation  Psychiatry Passive vs Active Nighttime Smartphone Use as Markers of Next-Day Suicide Risk Ross Jacobucci, Stephanie G. Jones, Miguel Blacutt, et al JAMA Netw Open 2025;8;(11):e2542675. doi:10.1001/jamanetworkopen.2025.42675 Key Points Question  Are the timing and type (passive vs active) of nighttime smartphone use associated with next-day suicidal ideation and suicide planning in high-...

Editorial  Postoperative Transfusion in Patients at High Cardiac Risk: Evidence, Uncertainty, and Nuance Jeremy W. Jacobs, Evan M. Bloch JAMA Published Online: November 8, 2025 doi: 10.1001/jama.2025.21559 For 3 decades, randomized trials have provided evidence for and steadily moved practice toward restrictive red blood cell (RBC) transfusion strategies (ie, transfusing at hemoglobin thresholds of 7-8 g/dL instead of 9-10 g/dL).1-3 With rare exception...

Original Investigation  Caffeinated Coffee Consumption or Abstinence to Reduce Atrial Fibrillation: The DECAF Randomized Clinical Trial Christopher X. Wong, Christopher C. Cheung, Gabrielle Montenegro, et al JAMA Published Online: November 9, 2025 doi: 10.1001/jama.2025.21056 Key Points Question  Does consumption of caffeinated coffee have a beneficial, detrimental, or neutral effect on the risk...