Original Investigation  Pediatrics March 25, 2025 Risk Factors for Health Care–Associated Bloodstream Infections in NICUs Julia Johnson, Sudhir Malwade, Sharad Agarkhedkar, et al JAMA Netw Open. 2025;8(3):e251821. doi:10.1001/jamanetworkopen.2025.1821 Key Points Question  What risk factors are associated with neonatal health care–associated bloodstream infections (BSIs) in low-resource settin...

Causes and Consequences of Physician Burnout and the Importance of Well-Being In ICU Mon, 10 Mar 2025 ICU Management & Practice, Volume 25 - Issue 1, 2025 Physician burnout has emerged as a critical issue in healthcare over the past few years, with significant implications for the entire system. This multifaceted problem stems from a combination of individual factors and systemic concerns. By addressing this issue comprehensively, healthcare sy...

Research Effects of a general practitioner-led brief narrative exposure intervention on symptoms of post-traumatic stress disorder after intensive care (PICTURE): multicentre, observer blind, randomised controlled trial Jochen Gensichen, Konrad F R Schmidt, Linda Sanftenberg, et al BMJ 2025; 389 doi: https://doi.org/10.1136/bmj-2024-082092 (Published 07 May 2025)Cite this as: BMJ 2025;389:e082092 Abstract Objective To d...

ONLINE FIRST (FREE ACCESS) ARTIFICIAL INTELLIGENCE IN ICU Editorial Stop asking if AI will replace ICU doctors! Start asking how it will radically transform their practiceGoulenok C., Kentish-Barnes N. & Bougouin W. THE BRAIN IN THE LINE OF FIRE What's New in Intensive Care Carbon dioxide pathophysiology and targets following acute brain injuryTaran S., Sekhon M. & Robba C. STANDARD OF CARE IN THE INTENSIVE CARE UNIT Narrative Review Atr...

Original Investigation  Surgery March 25, 2025 Patient Complexity and Bile Duct Injury After Robotic-Assisted vs Laparoscopic Cholecystectomy Cody Lendon Mullens, Sarah Sheskey, Jyothi R. Thumma, et al JAMA Netw Open. 2025;8(3):e251705. doi:10.1001/jamanetworkopen.2025.1705 Key Points Question  Are patient risk factors and complexity associated with differential rates of bile duct injury in r...

Risk Factors for Subsyndromal Delirium Progression and Mortality In ICU Tue, 25 Mar 2025 Delirium is common in critically ill patients and is linked to poor outcomes like prolonged hospital stays and cognitive impairment. Subsyndromal delirium (SSD) is an intermediate state between no delirium and full delirium, involving cognitive and behavioural abnormalities without meeting DSM-5 criteria for delirium. SSD affects about one-third of ICU patients and...

Original Investigation  March 24, 2025 Avoidable Mortality Across US States and High-Income Countries Irene Papanicolas, Maecey Niksch, Jose F. Figueroa JAMA Intern Med. Published online March 24, 2025. doi:10.1001/jamainternmed.2025.0155 Key Points Question  How did avoidable mortality vary across US states compared with 40 high-income countries between 2009 and 2021? Findings  In this ...

Editorial  Beyond Obstruction—A Milestone in COPD Diagnosis Francesca Polverino JAMA 2025;333;(24):2151-2153 doi:10.1001/jama.2025.6653 The landscape of chronic obstructive pulmonary disease (COPD) is changing rapidly. Thanks to long-term studies tracking lung function and the integration of advanced imaging and analytic tools, we now have a much deeper understanding of how COPD presents in different patients. The emergence of multiomic technologies ha...

A Multidimensional Diagnostic Approach for Chronic Obstructive Pulmonary Disease COPDGene 2025 Diagnosis Working Group and CanCOLD Investigators JAMA 2025;333;(24):2164-2175 doi:10.1001/jama.2025.7358 Key Points Question  Does incorporating chest computed tomographic imaging abnormalities and respiratory symptoms into the chronic obstructive pulmonary disease (COPD) diagnostic schema improve identification of individuals with poor respiratory outc...

Ventilation-Induced AKI in Acute Respiratory Failure In ICU Tue, 25 Mar 2025 Mechanical ventilation increases the risk of acute kidney injury (AKI) in critically ill patients, with studies indicating a three-fold higher risk compared to non-ventilated patients. The lung-kidney cross-talk during mechanical ventilation occurs through three primary mechanisms: (1) gas exchange abnormalities (hypoxaemia and hypercapnia) impair renal blood flow, (2) inflamm...