Original Investigation  Postoperative 20% Albumin Infusion and Acute Kidney Injury in High-Risk Cardiac Surgery Patients: The ALBICS AKI Randomized Clinical Trial Yahya Shehabi, Mayurathan Balachandran, Wisam Al-Bassam, et al JAMA Surg Published Online: June 11, 2025 doi: 10.1001/jamasurg.2025.1683 Key Points Question  Is the addition of 20% albumin infusion given postoperatively nephroprotectiv...

EDUCATION AND CLINICAL PRACTICE: ORIGINAL RESEARCH Impact of Noninvasive Ventilation Before and After Cardiac Surgery for Preventing Cardiac and Pulmonary Complications: A Clinical Randomized Trial Marion Goret, Kevin Pluchon, Raphaël Le Mao, et al Chest 2025; 167: 1727-1736 Abstract Background The immediate postoperative period after heart surgery poses a substantial risk of life-threatening complications, notably acute pulmonary and cardiac failure. Us...

Original Investigation  Surgery June 3, 2025 Three-Dimensional–Printed Models and Shared Decision-Making: A Cluster Randomized Clinical Trial Aimal Khan, Georgina E. Sellyn, Danish Ali, et al JAMA Netw Open. 2025;8(6):e2513187. doi:10.1001/jamanetworkopen.2025.13187 Key Points Question  Compared with usual care practices, does preoperative education for colorectal surgery aided by 3-dimension...

Monitoring of Patients With Acute Respiratory Failure During Non-Invasive Respiratory Support In ICU Tue, 15 Apr 2025 Acute respiratory failure (ARF) is characterised by hypoaxemia, which may be accompanied by hypoventilation, hypercapnia, or isolated acute hypoxaemic respiratory failure (AHRF). This condition results in an inability to deliver adequate oxygen to organs and remove CO2, leading to acid-base imbalances. Although supplemental oxygen can s...

Research A village doctor-led mobile health intervention for cardiovascular risk reduction in rural China: cluster randomised controlled trial Xingyi Zhang, Siming Wang, Xingyu Zhou, et al BMJ 2025; 389 doi: https://doi.org/10.1136/bmj-2024-082765 (Published 27 May 2025)Cite this as: BMJ 2025;389:e082765 Abstract Objective To assess the effectiveness of a village doctor-led mobile health intervention on cardiovas...

Original Investigation June 3, 2025 Transfusion Strategy Effect on Quality of Life in Patients With Myocardial Infarction and Anemia： A Secondary Analysis of the MINT Randomized Clinical Trial Micah T. Prochaska, Gerard T. Portela, Maria Mori Brooks, et al JAMA Intern Med. Published online June 3, 2025. doi:10.1001/jamainternmed.2025.0654 Key Points Question  Does a liberal (hemoglobin less than 10 ...

Research Incidence and prevalence of dementia among US Medicare beneficiaries, 2015-21: population based study Beau Blass, Cassie B Ford, Samir Soneji, et al BMJ 2025; 389 doi: https://doi.org/10.1136/bmj-2024-083034 (Published 20 May 2025)Cite this as: BMJ 2025;389:e083034 Abstract Objective To determine the incidence and prevalence of dementia in a nationally representative cohort of US Medicare beneficiaries, strat...

Targeted Normoxaemia and Supplemental Oxygen–Free Days In ICU Tue, 8 Apr 2025 Critically ill patients often receive supplemental oxygen to prevent hypoxaemia, but excessive oxygen can lead to harmful effects like oxidative damage and inflammation. While higher oxygen levels may provide a safety margin, they also increase the risk of hyperoxaemia, particularly in resource-limited settings. Recent trials in ICU patients without trauma found no mortali...

Original Investigation  June 2, 2025 Robotic vs Laparoscopic Surgery for Middle and Low Rectal Cancer: The REAL Randomized Clinical Trial Qingyang Feng, Weitang Yuan, Taiyuan Li, et al JAMA. Published online June 2, 2025. doi:10.1001/jama.2025.8123 Key Points Question  Can the use of robotic surgery reduce the locoregional recurrence rate of middle and low rectal cancer compared with the use of ...

Research Drug treatments for mild or moderate covid-19: systematic review and network meta-analysis Sara Ibrahim, Reed A C Siemieniuk, María José Oliveros, et al BMJ 2025; 389 doi: https://doi.org/10.1136/bmj-2024-081165 (Published 29 May 2025)Cite this as: BMJ 2025;389:e081165 Abstract Objective To compare the effects of treatments for mild or moderate (that is, non-severe) coronavirus disease 2019 (covid-19). ...