Review British Society for Medical Mycology best practice recommendations for the diagnosis of serious fungal diseases: 2025 update Silke Schelenz, Alireza Abdolrasouli, Darius Armstrong-James, et al Lancet Infect Dis Available online 10 November 2025 https://doi.org/10.1016/S1473-3099(25)00550-X Summary The fungal diagnostic landscape is evolving; whereas previously, traditional culture-based methods dominated, most invasive fungal disease is now diagno...

#LIVES2025: The Silent ICU  In ICU Tue, 28 Oct 2025 While therapeutic music addresses one aspect of the ICU soundscape, alarm management tackles another critical dimension. Margot Van Mol, Assistant Professor in Rotterdam, presented research on creating a smart and silent ICU that addresses the overwhelming alarm burden facing healthcare professionals and patients.  The statistics are sobering: ICU patients can be exposed to 100 to 1,000 a...

Articles Efficacy and safety of minocycline in patients with acute ischaemic stroke (EMPHASIS): a multicentre, double-blind, randomised controlled trial Yao Lu, Ling Guan, Jialing Wu, et al Lancet Available online 30 January 2026 https://doi.org/10.1016/S0140-6736(25)01862-8 Summary Background Minocycline has been reported as a multi-target anti-neuroinflammatory drug with potential benefits for ischaemic stroke in preclinical models and small-scale c...

ONLINE FIRST (FREE ACCESS) LATEST ARTICLES Original Sex, time, and disability status differences in mortality, multidimensional morbidity, and health care utilization: a secondary analysis of the Canadian RECOVER studyBurns, K.E.A., Huszti, E., Li, Q. et al. EditorialUpdate on infection: from prevention to diagnosis and managementNseir, S., Salluh, J.I.F. & Póvoa, P. Update on sepsis and septic shock: from bundles to precision medicinePlata-Menchaca, E....

#LIVES2025: The Role of Music in the ICU  In ICU Tue, 28 Oct 2025 The intensive care unit environment presents a paradox: while advanced monitoring technology is essential for patient care, the resulting noise pollution may harm the very patients it aims to protect. Two complementary approaches are emerging to address this challenge: therapeutic music interventions and innovative alarm management strategies that promise to...

Special Communication  Diagnosis and Treatment of Acute Appendicitis: 2025 Edition of the World Society of Emergency Surgery Jerusalem Guidelines Mauro Podda, Marco Ceresoli, Belinda De Simone, et al JAMA Surg Published Online: January 28, 2026 doi: 10.1001/jamasurg.2025.6218 Abstract Importance  Acute appendicitis is the most common abdominal surgical emergency worldwide and a leading cause of ...

Editor's Note  AI in Medicine AI Use in Research and the Need for Continued Guidance Preeti N. Malani, Joseph S. Ross JAMA Published Online: January 28, 2026 doi: 10.1001/jama.2025.26845 As artificial intelligence (AI) use proliferates, these tools have become an integral part of daily life for many people, including scientists. AI tools can review text to provide citations and optimize writing, perform data analysis, a...

Research Letter  AI in Medicine Self-Disclosed Use of AI in Research Submissions to BMJ Journals Isamme AlFayyad, Maurice P. Zeegers, Lex Bouter, et al JAMA Published Online: January 28, 2026 doi: 10.1001/jama.2025.25688 Artificial intelligence (AI), including generative AI, has rapidly emerged as a powerful tool in scientific research and publication.1 Current estimates of AI use rely on self-reported su...

Research Letter  AI in Medicine Author Disclosure of Use of AI in Submissions to 13 JAMA Network Journals Roy H. Perlis, Annette Flanagin, Jacob Kendall-Taylor, et al JAMA Published Online: January 28, 2026 doi: 10.1001/jama.2025.25300 The scientific community has not reached consensus about the appropriate application of artificial intelligence (AI) in manuscript preparation and review.1 In August 2023, JAMA ...

Original Investigation  US State-Level Prevalence of Adult Obesity by Race and Ethnicity From 1990 to 2022 and Forecasted to 2035 Nicole K. DeCleene, Ethan Kahn, Chun-Wei Yuan, et al JAMA Published Online: January 28, 2026 doi: 10.1001/jama.2025.26817 Key Points Question  What are the current and future estimates of obesity prevalence in the US by state, race and ethnicity group, sex, and age? ...