Original Investigation  Personalized Blood Pressure Targeting After Endovascular Therapy for Acute Ischemic Stroke: A Randomized Clinical Trial Pol Camps-Renom, Marina Guasch-Jiménez, Juan Álvarez-Cienfuegos, et al JAMA Neurol Published Online: June 8, 2026 doi: 10.1001/jamaneurol.2026.1706 Key Points Question  Does a reperfusion-guided systolic blood pressure control strategy improve functional...

Explainable AI in Sepsis Prediction Faces Biomarker Gap In Sepsis Wed, 29 Apr 2026 Sepsis remains a major cause of morbidity and mortality in intensive care settings, requiring timely identification to support intervention. A recent systematic review published in International Journal of Medical Informatics evaluates machine learning approaches for early detection and prediction of sepsis, focusing on model explainability and alignment with c...

JOURNAL ARTICLE Impact of Vancomycin-Resistant Enterococci (VRE)–Active Perioperative Prophylaxis in Liver Transplant Patients Colonized by VRE Giulia Jole Burastero, Emmanuel Q Wey, Veronica Guidetti, et al Clinical Infectious Diseases, Volume 82, Issue 5, 15 May 2026, Pages 878–887, https://doi.org/10.1093/cid/ciaf121 Abstract Background Data regarding the effectiveness of vancomycin-resistant Enterococci (VRE)–a...

JOURNAL ARTICLE Metagenomic Next-generation Sequencing of Cerebrospinal Fluid: First-year Experience at a Tertiary Referral Hospital Sergio Alvarez Mulett, Sofia Molina Garcia, Omar Abu Saleh, et al Clinical Infectious Diseases, Volume 82, Issue 5, 15 May 2026, Pages 808–814, https://doi.org/10.1093/cid/ciaf390 Abstract Background Central nervous system (CNS) infections are significant causes of morbidity and mortality, especially whe...

Gender Equality and Equity in Intensive Care In ICU Tue, 21 Apr 2026 An international study addressed gender equality and equity in intensive care medicine (ICM), a field where disparities persist despite increasing workforce diversity. The authors highlight that although women now comprise a substantial proportion of healthcare workers, leadership roles in intensive care remain disproportionately occupied by men.  Research has largely focused ...

nvited Commentary  Sleep, Burnout, and Surgery—Are Medical Errors an Adverse Effect? Jamie J. Coleman, Mitchell J. Cohen JAMA Surg Published Online: June 3, 2026 doi: 10.1001/jamasurg.2026.1807 Historically, sleep research and sleep hygiene recommendations have focused on sleep duration—the total amount of sleep obtained per night. Public health guidance has emphasized optimal ranges of sleep duration and promoted behaviors that help people achieve the...

Original Investigation  Anesthesiology Extended Work Periods Among Anesthesiologists and Postoperative Patient Outcomes Anjali A. Dixit, Ben Deverett, Eric C. Sun JAMA Netw Open 2026;9;(5):e2611644. doi:10.1001/jamanetworkopen.2026.11644 Key Points Question  Are extended work periods for anesthesiologists associated with worse postoperative patient outcomes? Findings  In this cross-sectional study...

Article The environmental cost of learning: CO2 emission comparisons of virtual reality, online, and alternative distance education Istrate, G.M., Van Gelder, F., Szőllősi, G.J. et al Intensive Care Med (2026). https://doi.org/10.1007/s00134-026-08460-z Abstract Purpose Environmental sustainability has become a critical concern across various sectors, including education and healthcare. Professional training programmes, particularly in intensive care med...

Reporting of Withdrawal of Life-Sustaining Treatment in Acute Brain Injury Trials In ICU Tue, 21 Apr 2026 There is an under-recognised methodological challenge in randomised clinical trials (RCTs) involving patients with acute brain injury (ABI): the impact of withdrawal of life-sustaining treatment (WLST) on trial validity and interpretation. WLST represents a significant and often inadequately reported source of bias that can distort estimates of tre...

Article Personalized automatic management of tracheal cuff pressure and subglottic secretions drainage to prevent pneumonia in critically ill intubated patients. The MICROINHALO multicenter randomized controlled trial De Pascale, G., Cutuli, S.L., Vargas, M. et al Intensive Care Med (2026). https://doi.org/10.1007/s00134-026-08459-6 Abstract Purpose: The MICROINHALO trial investigated whether personalized management of endotracheal tube cuff pressure (...