ARTICLES OF THE MONTH - APRIL 2019 ORIGINAL ~ Nasal high-flow preoxygenation for endotracheal intubation in the critically ill patient: a randomised clinical trial Guitton et al.: Nasal high-flow preoxygenation for endotracheal intubation in the critically ill patient: a randomised clinical trial This is the first randomised multicentre study comparing the use of HFNC with HFFM for the preoxygenation of non-severely hypoxemic patients in the ICU.  In thi...

Original Investigation February 6, 2019 Association Between Emergency Medical Service Response Time and Motor Vehicle Crash Mortality in the United States James P. Byrne, N. Clay Mann, Mengtao Dai, et al JAMA Surg. 2019;154(4):286-293. doi:10.1001/jamasurg.2018.5097 Abstract Importance 背景 Motor vehicle crashes (MVCs) are a leading public health concern. Emergency medical service (EMS) response time is a modi...

Comment & Response May 14, 2019 Acute Kidney Injury Related to Sepsis David S. Seres JAMA. 2019;321(18):1827-1828. doi:10.1001/jama.2019.2040 To the Editor 致编辑 Drs Legrand and Kellum reviewed the interpretation of serum creatinine in a critically ill patient.1 However, they only included a glancing reference to muscle mass and did not discuss protein intake. Both factors affect the evaluation of renal function and m...

Original Investigation May 14, 2019 Effect of Restriction of the Number of Concurrently Open Records in an Electronic Health Record on Wrong-Patient Order Errors: A Randomized Clinical Trial Jason S. Adelman, Jo R. Applebaum, Clyde B. Schechter, et al JAMA. 2019;321(18):1780-1787. doi:10.1001/jama.2019.3698 Abstract Importance 背景 Recommendations in the United States suggest limiting the number of p...

Original Investigation|Caring for the Critically Ill PatientMay 7, 2019 Effect of Trans-Nasal Evaporative Intra-arrest Cooling on Functional Neurologic Outcome in Out-of-Hospital Cardiac Arrest: The PRINCESS Randomized Clinical Trial Per Nordberg, Fabio Silvio Taccone, Anatolij Truhlar, et al JAMA. 2019;321(17):1677-1685. doi:10.1001/jama.2019.4149 Importance 背景 Therapeutic hypothermia may increase survival wit...

JAMA Network Clinical Guideline Synopsis April 17, 2019 The Society of Vascular Surgery Practice Guidelines on the Care of Patients With Abdominal Aortic Aneurysms Michol A. Cooper, Gilbert R. Upchurch Jr JAMA Surg. Published online April 17, 2019. doi:10.1001/jamasurg.2019.0566 Guideline title: The Society for Vascular Surgery Practice Guidelines on the Care of Patients with an Abdominal Aortic Aneurysm 指南标题：血管外科学会腹主动脉瘤患者诊...

#ISICEM19: Critical care medicine in space Dr. Matthieu Komorowski, Consultant in Intensive Care and Machine Learning researcher at Imperial College, London, talked about critical care in space at the 39th International Symposium on Intensive Care and Emergency Medicine.   One of the most distinct features about his talk (apart from the fact that it was about space), was that instead of presenting a lecture on space medicine, he narrated a story. The story is se...

Original Investigation January 16, 2019 Association Between Postoperative Delirium and Long-term Cognitive Function After Major Nonemergent Surgery C. Adrian Austin, Thomas O’Gorman, Elizabeth Stern, et al JAMA Surg. 2019;154(4):328-334. doi:10.1001/jamasurg.2018.5093 Abstract Importance 背景 Postoperative delirium is associated with decreases in long-term cognitive function in elderly populations. 老年人术后谵妄伴随远期认知功能减退。 Objectiv...

Acute-on-chronic liver failure: criteria for ICU admission Cirrhosis is a leading cause of morbidity and mortality throughout the world. Patients with cirrhosis may develop decompensated disease with portal hypertension and functional impairment of the liver, resulting in numerous complications including infection, variceal bleeding, hepatic encephalopathy (HE), and hepatorenal syndrome (HRS). Along with decompensation of cirrhosis, the concept of acute-on-chron...

亚洲ICU中肺保护性通气的国际多中心观察性研究 International Multi-Center Observational Study of Lung-protective Ventilation in Asian ICUs 请登陆IMPROVE study registration网站进行注册 研究目的 了解亚洲国家ICU中急性呼吸功能衰竭患者肺保护通气（如小潮气量，根据FiO2水平设置PEEP等）的依从性研究肺保护性通气依从性与ICU管理模式及患者预后的相关性研究入选患者符合ARDS诊断标准的比例以及医生的认知 研究方法 国际多中心观察性研究基于网络收集研究数据（包括参研ICU...