Original Investigation September 1, 2020 Effect of Intraoperative Low Tidal Volume vs Conventional Tidal Volume on Postoperative Pulmonary Complications in Patients Undergoing Major Surgery: A Randomized Clinical Trial Dharshi Karalapillai, Laurence Weinberg, Philip Peyton, et al JAMA. 2020;324(9):848-858. doi:10.1001/jama.2020.12866 Abstract 摘要 Importance 背景 In patients who undergo mechanical ventilation during surgery, the ideal tida...

Research Physical distancing interventions and incidence of coronavirus disease 2019: natural experiment in 149 countries Nazrul Islam, Stephen J Sharp, Gerardo Chowell, et al  BMJ 2020; 370: m2743 doi: https://doi.org/10.1136/bmj.m2743 (Published 15 July 2020) Abstract Objective 目的 To evaluate the association between physical distancing interventions and incidence of coronavirus disease 2019 (covid-19) globally. 评价物理距离措施与全球新冠肺炎(COVID...

ICU Management & Practice, Volume 20 - Issue 2, 2020 Nine Nurse-Recommended Design Strategies to Improve Alarm Management in the ICU: A Qualitative Study We asked intensive care nurses how they experience medical alarms in the critical care context and how they can help ideate strategies for better alarm management. Our study revealed that excessive medical alarms are one of the sources of discomfort at the workspace for critical care nurses and nurses’ wel...

ARTICLES| VOLUME 396, ISSUE 10250, P545-552, AUGUST 22, 2020 Venoarterial extracorporeal membrane oxygenation to rescue sepsis-induced cardiogenic shock: a retrospective, multicentre, international cohort study Nicolas Bréchot, David Hajage, Antoine Kimmoun, et al Lancet 2020; 396: 545-552 Summary Background 背景 Patients with sepsis-induced cardiomyopathy with cardiogenic shock have a high mortality. This study assessed venoarterial extracorporeal membr...

ICU Management & Practice, Volume 20 - Issue 2, 2020 The Night Falls in the ICU: Changing Realities for Patients, Relatives & Interdisciplinary Team Night has fallen in the intensive care unit, and the medical team is smaller. What do physicians, nurses and patients actually feel? An overview of the night falls in the ICU - from the perspective of an ICU team. Brief Description and Comparison with the Day-Time Atmosphere During the day and at nigh...

Original Investigation August 11, 2020 Effects of Liberal vs Restrictive Transfusion Thresholds on Survival and Neurocognitive Outcomes in Extremely Low-Birth-Weight Infants: The ETTNO Randomized Clinical Trial Axel R. Franz, Corinna Engel, Dirk Bassler, et al JAMA. 2020;324(6):560-570. doi:10.1001/jama.2020.10690 Abstract Importance Red blood cell transfusions are commonly administered to infants weighing less than 1000 g at birth. Eviden...

ICU Management & Practice, Volume 20 - Issue 2, 2020 Is the Severe COVID-19 Over in Europe? Is the worst over? Have patients most at risk already been affected and died? Or has the SAR-CoV-2 virus mutated to a less severe form? Where exactly do we stand with COVID-19? Undoubtedly, the COVID-19 pandemic has been a terrible experience - worse than expected for many worldwide. As we follow the COVID-19 situation, there is a tendency to focus on the many dea...

ICU Management & Practice, Volume 20 - Issue 2, 2020 Making Decisions During ICU Night Shifts: Challenges and Considerations We review the decision-making processes during night shifts focusing on the perspective of residents and fellows. We explore nighttime decisions about extubations, ICU discharge, withholding/withdrawing and night shift cross-coverage. Taking a night shift in the ICU can be challenging, particularly from a resident/fellow perspectiv...

Research Diagnostic accuracy of serological tests for covid-19: systematic review and meta-analysis Mayara Lisboa Bastos, Gamuchirai Tavaziva, Syed Kunal Abidi, et al BMJ 2020; 370: m2516 doi: https://doi.org/10.1136/bmj.m2516 (Published 01 July 2020) Abstract Objective 目的 To determine the diagnostic accuracy of serological tests for coronavirus disease-2019 (covid-19). 确定新冠病毒感染(COVID-19)血清学检查的诊断准确性。 Design 设计 Systematic ...

COVID-19: Molecular Mechanisms of Gender Differences The COVID-19 pandemic has resulted in hundreds of thousands of deaths around the globe. An important thing to note is that more men have died from COVID-19 than women. A European study shows that men had a slightly higher incidence of COVID-19 with no respiratory distress compared to women. Still, more males with COVID-19 developed severe respiratory failure compared to females. Other studies also show that men are m...