Research Letter July 14, 2020 Association Between Universal Masking in a Health Care System and SARS-CoV-2 Positivity Among Health Care Workers Xiaowen Wang, Enrico G. Ferro, Guohai Zhou, et al JAMA. Published online July 14, 2020. doi:10.1001/jama.2020.12897 The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has severely affected health care workers (HCWs).1 As a result, hos...

Imaging in Neurological Disease of Hospitalised COVID-19 Patients Originating in Wuhan, China, COVID-19 soon spread throughout the world and has been declared a pandemic by the World Health Organization. Italy was the second country to be hit as hard as China, with a total of 222,104 cases and 31,106 deaths (at time of publication). A study was conducted to understand the characteristics of neurological symptoms and neuroimaging features of COVID-19 patients admitte...

ICU Management & Practice, Volume 20 - Issue 1, 2020 Vasoactive Agent Management for Haemodynamic Support in COVID-19 Patients An overview of the Surviving Sepsis Guidelines for the vasoactive agent management of COVID-19 patients with septic shock and the use of arginine vasopressin in this patient population. The SARS-CoV-2 has caused a global health crisis. Thousands of people across the globe have been affected by COVID-19. Clinicians are in urgent n...

Reappraisal of Biomarkers in Sepsis Management Sepsis biomarkers have an important role in the diagnosis, prognosis, and treatment of sepsis management. If timely and accurate information about biomarkers becomes available, the physician can not only make better therapeutic choices but also monitor the efficacy of the intervention in progress and adjust it accordingly.   In a previous review published in 2010, researchers found 3370 references on 178 sepsi...

ARTICLES|ONLINE FIRST Seroprevalence of anti-SARS-CoV-2 IgG antibodies in Geneva, Switzerland (SEROCoV-POP): a population-based study Silvia Stringhini, Ania Wisniak, Giovanni Piumatti, et al Lancet Published: June 11, 2020 DOI:https://doi.org/10.1016/S0140-6736(20)31304-0 Summary Background Assessing the burden of COVID-19 on the basis of medically attended case numbers is suboptimal given its reliance on testing strategy, changing case definitions, and...

Mechanical Ventilation in COVID-19 There is no specific treatment for COVID-19 patients. For those who develop respiratory failure and are unable to oxygenate with non-invasive methods, critical care doctors are providing supportive therapy. Since the pandemic started, mechanical ventilation has routinely been employed to oxygenate seriously ill COVID-19 patients. Each hospital has developed its own criteria for identifying patients who require mechanical ven...

Prone Positioning in Non-Intubated COVID-19 Patients The COVID-19 pandemic has placed unprecedented stress on health care institutions everywhere. Among other interventions, researchers and physicians have been trying to reevaluate the use of mechanical ventilation. The rise of social media has accelerated the spread of biased information about therapies that have not been peer-reviewed and have little to no evidence about its efficacy. Therefore, the question is wheth...

Original Investigation Caring for the Critically Ill PatientJune 4, 2020 Association of Noninvasive Oxygenation Strategies With All-Cause Mortality in Adults With Acute Hypoxemic Respiratory Failure: A Systematic Review and Meta-analysis Bruno L. Ferreyro, Federico Angriman, Laveena Munshi, et al JAMA. 2020;324(1):57-67. doi:10.1001/jama.2020.9524 Abstract Importance Treatment with noninvasive oxygenation strategie...

COVID-19: Therapies Targeting Interleukin-6-Mediated Cytokine Release Syndrome The current pandemic will be remembered for a long time for the huge loss of lives and disruption it caused to the way of life as we know it. In the absence of a viable vaccine, physical distancing and symptomatic management are the only interventions health care providers have at hand. Studies have demonstrated the association of interleukin-6 (IL-6)-mediated cytokine release syndrome and m...

Effect of Hydroxychloroquine in Hospitalized Patients with COVID-19: Preliminary results from a multi-centre, randomized, controlled trial ABSTRACT Background 背景 Hydroxychloroquine and chloroquine have been proposed as treatments for coronavirus disease 2019 (COVID-19) on the basis of in vitro activity, uncontrolled data, and small randomized studies. 根据体外活性，非对照研究数据以及小样本随机试验，羟氯喹和氯喹被用于治疗新冠病毒感染(COVID-19)。 Methods 方...