ICU Management & Practice, Volume 21 - Issue 1, 2021 Cardiorespiratory Compromise in the Perioperative Environment - Prediction, Quality, Analytics & AI Perioperative cardiorespiratory compromise is common and goes largely undetected. Predictive cardiorespiratory indices can help in early detection of harmful deviations and guide preemptive treatment. Using continuous cardiorespiratory monitoring coupled with these tools, we now know which patients are ...

Original Investigation January 15, 2021 Comparison of Saliva and Nasopharyngeal Swab Nucleic Acid Amplification Testing for Detection of SARS-CoV-2: A Systematic Review and Meta-analysis Guillaume Butler-Laporte, Alexander Lawandi, Ian Schiller, et al JAMA Intern Med. 2021;181(3):353-360. doi:10.1001/jamainternmed.2020.8876 Abstract Importance Nasopharyngeal swab nucleic acid amplification testing (NAAT) is the non...

ICU Management & Practice, Volume 21 - Issue 1, 2021 Is Videolaryngoscopy the New Gold Standard for Intubation Following the COVID-19 Crisis? Videolaryngoscopy may be the new gold standard for tracheal intubation following the COVID-19 pandemic onset. Introduction Patients admitted to Intensive Care Units (ICU) often require respiratory support. Orotracheal intubation is one of the most frequent procedures performed in ICU (Lascarrou et al. 2017; Roux...

Original Investigation December 10, 2020 Evaluation of Cloth Masks and Modified Procedure Masks as Personal Protective Equipment for the Public During the COVID-19 Pandemic Phillip W. Clapp, Emily E. Sickbert-Bennett, James M. Samet, et al JAMA Intern Med. 2021;181(4):463-469. doi:10.1001/jamainternmed.2020.8168 Abstract Importance During the coronavirus disease 2019 (COVID-19) pandemic, the general public has been advi...

Selection Criteria for Lung Transplantation in COVID-19 Patients In May 2020, a team led by thoracic surgeon Konrad Hoetzenecker of the Department of Surgery of MedUni Vienna and Vienna General Hospital performed a lung transplant on a 44-year-old patient who had been seriously ill with COVID-19. She thus became the first patient in Europe to receive a lung transplant for this indication. The Vienna lung transplantation programme now plays a leading role in an i...

ORIGINAL ARTICLE A Novel Circulating MicroRNA for the Detection of Acute Myocarditis Rafael Blanco-Domínguez, Raquel Sánchez-Díaz, Hortensia de la Fuente, et al N Engl J Med 2021; 384:2014-2027DOI: 10.1056/NEJMoa2003608 Abstract BACKGROUND The diagnosis of acute myocarditis typically requires either endomyocardial biopsy (which is invasive) or cardiovascular magnetic resonance imaging (which is not universally available). Additional approaches to diagnos...

Impact of Stress and Shortages on Critical Care Physicians As hospitals continue to struggle with accelerating rates of coronavirus infections, hospitalisations, and deaths, the impact of the pandemic and the experiences of critical care physicians caring for the sickest COVID-19 patients should be examined. This is especially important because infection rates are increasing, and there are concerns about the capacity of the acute care system to care for severely il...

ORIGINAL ARTICLE Antibiotic Therapy for 6 or 12 Weeks for Prosthetic Joint Infection Louis Bernard, Cédric Arvieux, Benoit Brunschweiler, et al N Engl J Med 2021; 384:1991-2001DOI: 10.1056/NEJMoa2020198 Abstract BACKGROUND The management of prosthetic joint infection usually consists of a combination of surgery and antimicrobial therapy. The appropriate duration of antimicrobial therapy for this indication remains unclear. METHODS We performed...

Association Between Pre-Existing Respiratory Disease and COVID-19 Pre-existing respiratory disease could worsen the severity of COVID-19. A review of cases has shown that the prevalence of chronic respiratory disease in hospitalised COVID-19 patients was lower compared to prevalence in the general population. Another systematic review found mixed evidence on asthma. Some data suggests hospitalisation was equally probable, but disease severity might be more severe. ...

EORTC/MSGERC Definitions of Invasive Fungal Diseases: Summary of Activities of the Intensive Care Unit Working Group Matteo Bassetti, Elie Azoulay, Bart-Jan Kullberg, et al Clin Infect Dis 2021; 72(S2): S121-7 INVASIVE CANDIDIASIS Defining Proven and Probable Invasive Candidiasis in the Intensive Care Unit After several rounds of review and discussion, the proposed definition for proven IC by the ICU Working Group required definitive evidence of the organis...