ARTICLES|ONLINE FIRST Phenotyping of idiopathic pulmonary arterial hypertension: a registry analysis Marius M Hoeper, Krit Dwivedi, Christine Pausch, et al. Lancet Respir Med Published:June 28, 2022 DOI:https://doi.org/10.1016/S2213-2600(22)00097-2 Summary Background Among patients meeting diagnostic criteria for idiopathic pulmonary arterial hypertension (IPAH), there is an emerging lung phenotype characterised by a low diffusion capacity f...

#EA22: Impact of Anaesthesia Handover on Morbidity and Mortality What is the effect of intraoperative handover of anesthesia care on clinical outcomes? This was discussed in a very interesting session at Euroanaesthesia Congress this week. Prof Melanie Meersch-Dini of University Hospital Münster, Germany, reviewed the findings from the HandiCAP trial, published this week in JAMA.  Intraoperative handovers of anaesthesia care are quite common. While handover...

ARTICLES|ONLINE FIRST Association between women's authorship and women's editorship in infectious diseases journals: a cross-sectional study Katharina Last, Lilith Hübsch, Muge Cevik, et al. Lancet Infect Dis Published:July 12, 2022 DOI:https://doi.org/10.1016/S1473-3099(22)00367-X Summary Background Gender inequity is still pervasive in academic medicine, including journal publishing. We aimed to ascertain the proportion of women among first and last...

ARTICLES|ONLINE FIRST Impact of interactive computerised decision support for hospital antibiotic use (COMPASS): an open-label, cluster-randomised trial in three Swiss hospitals Gaud Catho, Julien Sauser, Valentina Coray, et al. Lancet Infect Dis Published:July 20, 2022 DOI:https://doi.org/10.1016/S1473-3099(22)00308-5 Summary Background Computerised decision-support systems (CDSSs) for antibiotic stewardship could help to assist physicians in the app...

ARTICLES| VOLUME 400, ISSUE 10349, P359-368, JULY 30, 2022 Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis RECOVERY Collaborative Group Lancet 2022; 400: 359-368 Published:July 30, 2022 DOI:https://doi.org/10.1016/S0140-6736(22)01109-6 Summary Background We aimed to evaluate the use of baricitinib, a Janus kinase (JAK) 1–2 inhibitor, fo...

#EA22: Reducing the Carbon Footprint of Anaesthetics Dr Nicolaas Hendrik Sperna Weiland, anaesthesiologist, Amsterdam University Medical Center, The Netherlands, and founder of the centre's Sustainable Healthcare Team discussed the environmental impact of inhaled anaesthetic agents and the need to massively reduce their use at this year's Euroanaesthesia Congress.  Volatile anaesthetics are potent greenhouse gases with a global warming potential (GWP) from ...

ONLINE FIRST (FREE ACCESS) OPEN ACCESS ~ Original How doctors manage conflicts with families of critically ill patients during conversations about end-of-life decisions in neonatal, pediatric, and adult intensive careSpijkers A.S. et al. Ventilatory settings in the initial 72 h and their association with outcome in out-of-hospital cardiac arrest patients: a preplanned secondary analysis of the targeted hypothermia versus targeted normothermia after out-of-hospital c...

Research Letter  July 22, 2022 Association Between Vaccination and Acute Myocardial Infarction and Ischemic Stroke After COVID-19 Infection Young-Eun Kim, Kyungmin Huh, Young-Joon Park, et al JAMA. Published online July 22, 2022. doi:10.1001/jama.2022.12992 Studies have suggested an increased incidence of acute myocardial infarction (AMI) and ischemic stroke after COVID-19 infection related to an increased risk of thrombosis.1,2 Vaccines...

ICU Management & Practice, Volume 22 - Issue 3, 2022 Pain Management Specificities in Critically Ill Patients With Obesity In patients with obesity, standard, non-weight-based dosing, or weight-based dosing using either ideal body weight or adjusted body weight, is appropriate to limit the risk of overdosing. The prevalence of obesity is increasing worldwide (Schetz et al. 2019). This trend is confirmed in the Intensive Care Unit (ICU) where patients wit...

Original Investigation  July 7, 2022 Changes in the Relationship Between Income and Life Expectancy Before and During the COVID-19 Pandemic, California, 2015-2021 Hannes Schwandt, Janet Currie, Till von Wachter, et al JAMA. 2022;328(4):360-366. doi:10.1001/jama.2022.10952 Key Points Question  How did the first 2 years of the COVID-19 pandemic affect life expectancy in California and the relationship between census tract income and life exp...