Original Investigation  December 27, 2022 Association of Family Income With Morbidity and Mortality Among US Lower-Income Children and Adolescents Victoria Udalova, Vinayak Bhatia, Maria Polyakova JAMA. 2022;328(24):2422-2430. doi:10.1001/jama.2022.22778 Key Points Question  Among children and adolescents from lower-income families in the US, is family income associated with health? Findings  This cross-sectional stu...

BEST OF JAMA NETWORK Most Viewed Articles 2022 – JAMA Read the most popular JAMA articles in 2022 covering the ongoing COVID-19 pandemic, the latest US Preventive Services Task Force recommendations, management of acute coronary syndromes, and more. COVID-19 False-Positive Results in Rapid Antigen Tests for SARS-CoV-2JAMA Research LetterFebruary 1, 2022 Myocarditis Cases Reported After mRNA-Based COVID-19 Vaccination in the US From December 2020 to Au...

Medical News & Perspectives  December 27, 2022 JAMA Network Articles of the Year 2022 Melissa Suran JAMA. 2022;328(24):2381-2385. doi:10.1001/jama.2022.17761 For our sixth annual Articles of the Year roundup, we considered all Original Investigations, Special Communications, and Brief Reports published across the JAMA Network from October 1, 2021, through September 30, 2022, and ranked them based on online views. Editors from each journal...

Continuous Cuff Pressure Control in Preventing Ventilator-Associated Pneumonia Patients in the ICU often require invasive mechanical ventilation support. This requires tracheal intubation, where an endotracheal cuff wrapped around the tip of the tube seals the extraluminal airway for positive pressure ventilation. Inappropriate cuff pressure control can contribute to ventilator-associated complications. Studies report that approximately 10–20% of long-term (≥ 48 hr...

EDITORIAL Extracorporeal CPR in Out-of-Hospital Cardiac Arrest — Still on Life Support? John F. Keaney, Jr., Thomas Münzel N Engl J Med 2023; 388:370-371DOI: 10.1056/NEJMe2214116 Despite many advances in the treatment of heart disease over the past four decades, up to one third of all patients with acute manifestations of heart disease do not reach the hospital after cardiac arrest. Only 8 to 10% of patients with out-of-hospital cardiac arrest survive; the eve...

ARTICLES|ONLINE FIRST The effect of higher protein dosing in critically ill patients with high nutritional risk (EFFORT Protein): an international, multicentre, pragmatic, registry-based randomised trial Daren K Heyland, Jayshil Patel, Charlene Compher, et al. Lancet Published:January 25, 2023 DOI:https://doi.org/10.1016/S0140-6736(22)02469-2 Summary Background On the basis of low-quality evidence, international critical care nutrition guidelines reco...

CRITICAL CARE: ORIGINAL RESEARCH| VOLUME 162, ISSUE 5, P1063-1073, NOVEMBER 01, 2022 Outcomes and Predictors of 28-Day Mortality in Patients With Solid Tumors and Septic Shock Defined by Third International Consensus Definitions for Sepsis and Septic Shock Criteria John A. Cuenca, Nirmala K. Manjappachar, Claudia M. Ramírez, et al Chest 2022; 162: 1063-1073 Published:May 26, 2022 DOI:https://doi.org/10.1016/j.chest.2022.05.017 Background D...

Dexamethasone and Oxygen Support Strategies for COVID-19 Hypoxaemic Respiratory Failure Acute hypoxaemic respiratory failure (AHRF) is one of the main manifestations of severe COVID-19. The RECOVERY trial showed that dexamethasone 6 mg/d for ten days reduced 28-day mortality in patients with the most severe COVID-19. Another study described the benefit of high-dose dexamethasone in ARDS. However, Munch et al. found no difference between high-dose and low-dose dexam...

ORIGINAL ARTICLE Early Extracorporeal CPR for Refractory Out-of-Hospital Cardiac Arrest Martje M. Suverein, Thijs S.R. Delnoij, Roberto Lorusso, et al N Engl J Med 2023; 388:299-309DOI: 10.1056/NEJMoa2204511 Abstract BACKGROUND Extracorporeal cardiopulmonary resuscitation (CPR) restores perfusion and oxygenation in a patient who does not have spontaneous circulation. The evidence with regard to the effect of extracorporeal CPR on survival with a favorabl...

Research Retracted papers originating from paper mills: cross sectional study Cristina Candal-Pedreira, Joseph S Ross, Alberto Ruano-Ravina, et al BMJ 2022; 379 doi: https://doi.org/10.1136/bmj-2022-071517 (Published 28 November 2022)Cite this as: BMJ 2022;379:e071517 Abstract Objectives To describe retracted papers originating from paper mills, including their characteristics, visibility, and impact over time, and the journals in which they were publi...