European Guidelines: Management of Bleeding, Coagulopathy Following Trauma According to the Global Burden of Diseases, Injuries, and Risk Factors Study, trauma accounted for 8% of total deaths annually. Among adolescents aged 10-24 years, road injuries, self-harm, and interpersonal violence are the top causes of disability-adjusted life-years, and road injuries are ranked first in the 25-49 year age group. Post-traumatic bleeding and associated traumatic coagulopat...

ARTICLES|ONLINE FIRST Incidence of infection with multidrug-resistant Gram-negative bacteria and vancomycin-resistant enterococci in carriers: a systematic review and meta-regression analysis Roel P J Willems, Karin van Dijk, Maria J G T Vehreschild, et al Lancet Infect Dis Published:January 30, 2023 DOI:https://doi.org/10.1016/S1473-3099(22)00811-8 Summary Background Carriers of multidrug-resistant bacteria are at risk of infections with these bacter...

ARTICLES|ONLINE FIRST Efficacy and safety of antimicrobial stewardship prospective audit and feedback in patients hospitalised with COVID-19 (COVASP): a pragmatic, cluster-randomised, non-inferiority trial Justin Z Chen, Holly L Hoang, Maryna Yaskina, et al Lancet Infect Dis Published:January 27, 2023 DOI:https://doi.org/10.1016/S1473-3099(22)00832-5 Summary Background The COVID-19 pandemic has been associated with increased antimicrobial use despite ...

ARTICLES|ONLINE FIRST Guideline adherence and survival of patients with candidaemia in Europe: results from the ECMM Candida III multinational European observational cohort study Martin Hoenigl, Jon Salmanton-García, Matthias Egger, et al Lancet Infect Dis Published:February 15, 2023 DOI:https://doi.org/10.1016/S1473-3099(22)00872-6 Summary Background The European Confederation of Medical Mycology (ECMM) collected data on epidemiology, risk ...

Prehospital Physician Presence During Paediatric OHCA A study was conducted to investigate whether the presence of prehospital physicians affected the neurological outcomes of paediatric patients who experienced an out-of-hospital cardiac arrest (OHCA). The study included paediatric patients who were 17 years old or younger and were registered in a database between June 2014 and December 2019.  The researchers used logistic regression models and stabil...

ARTICLES|ONLINE FIRST Prevention of non-ventilator-associated hospital-acquired pneumonia in Switzerland: a type 2 hybrid effectiveness–implementation trial Aline Wolfensberger, Lauren Clack, Stefanie von Felten, et al Lancet Infect Dis Published:March 06, 2023 DOI:https://doi.org/10.1016/S1473-3099(22)00812-X Summary Background Non-ventilator-associated hospital-acquired pneumonia (nvHAP) is a frequent, but under-researched infection. We aimed to sim...

ARTICLES|ONLINE FIRST Performance of antigen lateral flow devices in the UK during the alpha, delta, and omicron waves of the SARS-CoV-2 pandemic: a diagnostic and observational study David W Eyre, Matthias Futschik, Sarah Tunkel, et al Lancet Infect Dis Published:March 28, 2023 DOI:https://doi.org/10.1016/S1473-3099(23)00129-9 Summary Background Antigen lateral flow devices (LFDs) have been widely used to control SARS-CoV-2. We aimed to improve under...

Early Tracheostomy vs Late Tracheostomy in Traumatic Brain Injury, Stroke A recent review aimed to determine whether early tracheostomy benefits patients with severe traumatic brain injury (TBI) and stroke and whether these benefits persist across different underlying conditions. The included studies in the review were those written in English, French, Spanish, or Portuguese and with a formulated question that compared outcomes between early and late tracheostom...

ARTICLES| VOLUME 23, ISSUE 5, P589-597, MAY 2023 Clinical features and management of individuals admitted to hospital with monkeypox and associated complications across the UK: a retrospective cohort study Douglas L Fink, Helen Callaby, Akish Luintel, et al. Lancet Infect Dis 2023; 23: 589-597 Published:December 22, 2022 DOI:https://doi.org/10.1016/S1473-3099(22)00806-4 Summary Background The scale of the 2022 global mpox (formerly know...

ARTICLES| VOLUME 23, ISSUE 5, P556-567, MAY 2023 Protective effectiveness of previous SARS-CoV-2 infection and hybrid immunity against the omicron variant and severe disease: a systematic review and meta-regression Niklas Bobrovitz, Harriet Ware, Xiaomeng Ma, et al. Lancet Infect Dis 2023; 23: 556-567 Published:January 18, 2023 DOI:https://doi.org/10.1016/S1473-3099(22)00801-5 Summary Background The global surge in the omicron (B.1.1.529) variant has ...