Original Investigation  August 15, 2023 Prenatal Intravenous Magnesium at 30-34 Weeks’ Gestation and Neurodevelopmental Outcomes in Offspring: The MAGENTA Randomized Clinical Trial Caroline A. Crowther, Pat Ashwood, Philippa F. Middleton, et al JAMA. 2023;330(7):603-614. doi:10.1001/jama.2023.12357 Key Points Question  Does intravenous magnesium sulfate for pregnant individuals at risk of delive...

#EA23 - ESAIC Glasgow Declaration on Anaesthesiology and Intensive Care The European Society of Anaesthesiology and Intensive Care (ESAIC) Glasgow Declaration on Anaesthesiology and Intensive Care (EGD) was officially signed today during the inauguration of the Exhibition at #EA23 the Dear Green Place. This marks a monumental moment in healthcare history.  The European Union (EU) is dedicated to addressing climate change. The European Green Deal initiative ...

Original Investigation  July 17, 2023 Donanemab in Early Symptomatic Alzheimer Disease: The TRAILBLAZER-ALZ 2 Randomized Clinical Trial John R. Sims, Jennifer A. Zimmer, Cynthia D. Evans, et al JAMA. 2023;330(6):512-527. doi:10.1001/jama.2023.13239 Key Points Question  Does donanemab, a monoclonal antibody designed to clear brain amyloid plaque, provide clinical benefit in early symptomatic Alzheimer...

Original Investigation  August 8, 2023 Sugar-Sweetened and Artificially Sweetened Beverages and Risk of Liver Cancer and Chronic Liver Disease Mortality Longgang Zhao, Xinyuan Zhang, Mace Coday, et al JAMA. 2023;330(6):537-546. doi:10.1001/jama.2023.12618 Key Points Question  Is greater intake of sugar-sweetened beverages associated with greater risk of liver cancer or chronic liver disease mort...

Invited Commentary  August 2, 2023 Magic Pen?—An Innovative Adjunct for Intraoperative Identification of Parathyroid Glands Michelle B. Mulder, Quan-Yang Duh JAMA Surg. Published online August 2, 2023. doi:10.1001/jamasurg.2023.3257 DeHoog et al1 introduce the MasSpec Pen (MSPen), a new technology that uses real-time mass spectroscopy for intraoperative parathyroid identification. This device is able to distinguish among parathyroid, thy...

ONLINE FIRST (FREE ACCESS) LATEST ARTICLES OPEN ACCESS ~ OriginalEpidemiology of surgery associated acute kidney injury (EPIS-AKI): a prospective international observational multi-center clinical studyZarbock A. et al.  ECMO PAL: using deep neural networks for survival prediction in venoarterial extracorporeal membrane oxygenationStephens A.F. et al. Influence of socio-economic status on functional recovery after ARDS caused by SARS-CoV-2: the multicentre...

Original Investigation  Association of VA Surgeons May 17, 2023 Rates of National Institutes of Health Funding for Surgeon-Scientists, 1995-2020 Mytien Nguyen, Luis Gonzalez, Ashley Newman, et al JAMA Surg. 2023;158(7):756-764. doi:10.1001/jamasurg.2023.1571 Key Points Question  How has National Institutes of Health (NIH) funding to surgeon-scientists changed between 1995 and 2020? Findings &nb...

Invited Commentary  April 26, 2023 Optimizing Hemostatic Resuscitation in Trauma—Will Endotyping Be the Key to the “Proper” Ratio? Purvi P. Patel, Matthew J. Martin JAMA Surg. 2023;158(7):736-737. doi:10.1001/jamasurg.2023.0825 “Measure what is measurable, and make measurable what is not so.”1(p301) Galileo Galilei Trauma endotypes (TEs) characterize patients based on dynamic changes in immune and inflammatory biomarkers after injury.2,3 ...

Invited Commentary  August 2, 2023 Should We Care About Hospital Consolidation? Christopher P. Childers, Beverley A. Petrie, Christian de Virgilio JAMA Surg. Published online August 2, 2023. doi:10.1001/jamasurg.2023.3256 Competition among businesses is thought to benefit the consumer. With the recent surge in hospital mergers, there is concern that competition is being stifled and that costs may increase without a concomitant improvement in ...

Personalising Fluid Therapy in Septic Shock Volume expansion, the initial therapeutic measure for septic shock, involves the intravenous injection of a few hundred millilitres of fluid over a few minutes. However, using fluids in septic patients is a complex strategy, with various types of fluids available. The effects of fluid boluses are inconsistent and transient, and fluids carry risks, especially during septic shock. There are also questions about which fluid ...