Original Investigation  July 25, 2023 Identifying Children Likely to Benefit From Antibiotics for Acute Sinusitis: A Randomized Clinical Trial Nader Shaikh, Alejandro Hoberman, Timothy R. Shope, et al JAMA. 2023;330(4):349-358. doi:10.1001/jama.2023.10854 Key Points Question  In children aged 2 to 11 years with acute sinusitis, does the efficacy of antibiotic treatment differ based on nasopharyn...

Research Associations between self-reported healthcare disruption due to covid-19 and avoidable hospital admission: evidence from seven linked longitudinal studies for England Mark A Green, Martin McKee, Olivia KL Hamilton, et al BMJ 2023; 382 doi: https://doi.org/10.1136/bmj-2023-075133 (Published 19 July 2023)Cite this as: BMJ 2023;382:e075133 Abstract Objectives To examine whether there is an association between people who experienced disrupted acce...

Research Evaluating trends in private equity ownership and impacts on health outcomes, costs, and quality: systematic review Alexander Borsa, Geronimo Bejarano, Moriah Ellen, et al BMJ 2023; 382 doi: https://doi.org/10.1136/bmj-2023-075244 (Published 19 July 2023)Cite this as: BMJ 2023;382:e075244 Abstract Objective To review the evidence on trends and impacts of private equity (PE) ownership of healthcare operators. Design Systematic review. ...

High vs Low Mean Arterial Pressure in Cirrhosis Patients A new study assessed the impact of high mean arterial pressure (MAP) on renal outcomes in critically ill cirrhosis patients with septic shock (CIC). The efficacy of a high MAP strategy (80-85 mm Hg; H-MAP) was compared to a low MAP strategy (60-65 mm Hg; L-MAP) in improving 28-day mortality in CIC. Additionally, the study examined the reversal of shock, the occurrence of acute kidney injury (AKI) by day 5, th...

Viewpoint  July 18, 2023 Physical Activity for Health—Every Minute Counts Peter T. Katzmarzyk, John M. Jakicic JAMA. 2023;330(3):213-214. doi:10.1001/jama.2023.11014 Public health guidelines for physical activity provide evidence-based recommendations for the amount, intensity, and types of physical activity that should be undertaken to obtain and maintain health benefits. The Physical Activity Guidelines for Americans, 2nd Edition, reco...

Research Educational inequalities in mortality and their mediators among generations across four decades: nationwide, population based, prospective cohort study based on the ChinaHEART project Jiapeng Lu, Chaoqun Wu, Xiaoyan Zhang, et al BMJ 2023; 382 doi: https://doi.org/10.1136/bmj-2022-073749 (Published 19 July 2023)Cite this as: BMJ 2023;382:e073749 Abstract Objectives To assess the different educational inequalities in mortality among generations ...

ICU Management & Practice, Volume 23 - Issue 2, 2023 Biomarkers as Prognostic Predictors and Guide in Critically Ill Patients An overview of promising biomarkers in critical care, characteristics a biomarker should have and how to ensure their usefulness in clinical practice. Introduction Precision medicine is a medical approach that tailors treatments based on individual patient characteristics and their unique response to therapies for a particular ...

Original Investigation  July 18, 2023 Accelerometer-Derived “Weekend Warrior” Physical Activity and Incident Cardiovascular Disease Shaan Khurshid, Mostafa A. Al-Alusi, Timothy W. Churchill, et al JAMA. 2023;330(3):247-252. doi:10.1001/jama.2023.10875 Key Points Question  Does engagement in moderate to vigorous physical activity, with most activity concentrated within 1 to 2 days of the week (ie, a “weekend warrior” pattern), con...

CHEST INFECTIONS: ORIGINAL RESEARCH| VOLUME 163, ISSUE 1, P77-88, JANUARY 2023Download Full Issue Machine-Learning Model for Mortality Prediction in Patients With Community-Acquired Pneumonia: Development and Validation Study Catia Cilloniz, Logan Ward, Mads Lause Mogensen, et al Chest 2023; 163: 77-88 Published:July 15, 2022 DOI:https://doi.org/10.1016/j.chest.2022.07.005 Background Artificial intelligence tools and techniques such as machine learning (...

Research Prevalence and predictors of data and code sharing in the medical and health sciences: systematic review with meta-analysis of individual participant data Daniel G Hamilton, Kyungwan Hong, Hannah Fraser, et al BMJ 2023; 382 doi: https://doi.org/10.1136/bmj-2023-075767 (Published 11 July 2023)Cite this as: BMJ 2023;382:e075767 Abstract Objectives To synthesise research investigating data and code sharing in medicine and health to establish an a...