Tranexamic Acid for Intracerebral Haemorrhage in Patients on NOAC There is a lack of evidence-based haemostatic treatment for intracerebral haemorrhage (ICH) associated with non-vitamin K antagonist oral anticoagulants (NOACs). Tranexamic acid (TXA) is an antifibrinolytic drug that helps limit haematoma expansion. A study was conducted to evaluate the effectiveness and safety of using TXA in NOAC-related ICH cases. The trial was performed at six Swiss stroke centres...

Research Association between changes in carbohydrate intake and long term weight changes: prospective cohort study Yi Wan, Deirdre K Tobias, Kristine K Dennis, et al BMJ 2023; 382 doi: https://doi.org/10.1136/bmj-2022-073939 (Published 27 September 2023)Cite this as: BMJ 2023;382:e073939 Abstract Objective To comprehensively examine the associations between changes in carbohydrate intake and weight change at four year intervals. Design Prospect...

Invited Commentary  Pediatrics July 20, 2020 Leveraging Tweets, Citations, and Social Networks to Improve Bibliometrics N. Seth Trueger, Yusuf Yilmaz, Teresa M. Chan JAMA Netw Open. 2020;3(7):e2010911. doi:10.1001/jamanetworkopen.2020.10911 Citations have long been the leading metric for articles, with the citation-based journal impact factor being the primary journal metric. As the world becomes increasingly digital, altmetrics (“alternat...

Research Letter  September 29, 2023 Randomized Clinical Trial Visual Abstract Display and Social Media–Driven Website Traffic N. Seth Trueger, Eman Aly, Sebastien Haneuse, et al JAMA. Published online September 29, 2023. doi:10.1001/jama.2023.16839 Since 2016, medical journals have been using visual abstracts (VAs) to promote research on social media.1 VAs use images and text to efficiently convey a study’s methods and findings. Prior sm...

Research Letter  November 2, 2023 Changes in Employment in the US Health Care Workforce, 2016-2022 Thuy Nguyen, Christopher Whaley, Kosali I. Simon, et al JAMA. Published online November 2, 2023. doi:10.1001/jama.2023.18932 The COVID-19 pandemic has caused a variety of disruptions to the health care workforce.1 Data on select health care workforce sectors chronicle patterns in employment through 2021.1-3 Lack of national studies on ...

Editorial  October 25, 2023 Vitamin C for Patients With COVID-19: More Evidence of Lack of Efficacy in Patients With Sepsis Craig S. Jabaley, Craig M. Coopersmith JAMA. Published online October 25, 2023. doi:10.1001/jama.2023.18592 Vitamin C is an essential nutrient, functioning as an antioxidant, immunomodulator, and cofactor for numerous enzymes. Vitamin C represents the definitive treatment for scurvy, which results from vitamin C deficien...

ORIGINAL ARTICLE Ceftobiprole for Treatment of Complicated Staphylococcus aureus Bacteremia Thomas L. Holland, Sara E. Cosgrove, Sarah B. Doernberg, et al N Engl J Med September 27, 2023DOI: 10.1056/NEJMoa2300220 Abstract BACKGROUND Ceftobiprole is a cephalosporin that may be effective for treating complicated Staphylococcus aureusbacteremia, including methicillin-resistant S. aureus. METHODS In this phase 3, double-blind, doubl...

Editorial  October 25, 2023 Sigh Breaths for Trauma Patients Receiving Mechanical Ventilation: Take a Deep Breath Giacomo Bellani, Antonio Pesenti JAMA. Published online October 25, 2023. doi:10.1001/jama.2023.21744 Occasionally, newspapers report positive stories of animal species believed to be extinct, only to be discovered alive and repopulating their habitats.1 In this issue of JAMA, Albert and colleagues2 assessed the rol...

The Promise of Artificial Intelligence in Critical Care Computer-based technologies, including artificial intelligence (AI) applications like ChatGPT and DALL-E, are being increasingly used and can mimic human capabilities, even passing medical board examinations. Retrospective studies have shown that machine learning (ML) applications are especially valuable in the ICU due to their diagnostic and prognostic capabilities, leveraging the vast amount of available dat...

ARTICLES|ONLINE FIRST Multiorgan MRI findings after hospitalisation with COVID-19 in the UK (C-MORE): a prospective, multicentre, observational cohort study The C-MORE/PHOSP-COVID Collaborative Group Lancet Respir Med Published:September 22, 2023 DOI:https://doi.org/10.1016/S2213-2600(23)00262-X Summary Introduction The multiorgan impact of moderate to severe coronavirus infections in the post-acute phase is still poorly understood. We aimed to evalua...