EDITORIAL Universal Decolonization in Nursing Homes — Apparent Benefits but Feasible? Morgan J. Katz, Sara E. Cosgrove N Engl J Med 2023; 389:1815-1816DOI: 10.1056/NEJMe2311215 Nursing homes house a population most at risk for prolonged colonization with multidrug resistant organisms (MDROs) owing to the residents’ older age, repeat health care and antibiotic exposures, and ongoing contact with other persons with colonization.1 Although nursing homes pose...

ORIGINAL ARTICLE Decolonization in Nursing Homes to Prevent Infection and Hospitalization Loren G. Miller, James A. McKinnell, Raveena D. Singh, et al N Engl J Med October 10, 2023DOI: 10.1056/NEJMoa2215254 Abstract BACKGROUND Nursing home residents are at high risk for infection, hospitalization, and colonization with multidrug-resistant organisms. METHODS We performed a cluster-randomized trial of universal decolonization as compared with ro...

EDITORIAL| VOLUME 164, ISSUE 4, P826-828, OCTOBER 2023 Breaking a Sweat to Catch Your Breath: Exercise Therapy Improves Dyspnea After Acute Pulmonary Embolism Alexander E. Sullivan, Evan L. Brittain Chest 2023; 164: 826-828 DOI:https://doi.org/10.1016/j.chest.2023.05.033 Acute pulmonary embolism (PE) is a sentinel event for many patients; despite guideline-directed treatment of the acute event, up to 50% of patients will experience a pattern of dyspnea...

Research Letter  Climate Change and Health September 21, 2023 Canadian Wildfire Smoke and Asthma Syndrome Emergency Department Visits in New York City Kai Chen, Yiqun Ma, Michelle L. Bell, et al JAMA. 2023;330(14):1385-1387. doi:10.1001/jama.2023.18768 The wildfires in Canada in 20231 deteriorated air quality locally and distantly. For example, the smoke of wildfires in Quebec drifted into New York City (NYC), hundreds of kilometers away, and c...

Critical Care Staffing in Pandemics The COVID-19 pandemic has had significant impact on healthcare, with millions of cases and deaths reported globally. Healthcare workers have been particularly affected, experiencing increased mental health issues, burnout, and moral distress. The pandemic has led to higher levels of anxiety, depression, stress reactions, sleep disturbances, and posttraumatic stress disorder among healthcare staff. Prolonged exposure to high-inten...

Teachable Moment  February 13, 2023 Time-Limited Trials of Intensive Care Unit Care John J. Popovich, Isadore Budnick, Thanh H. Neville JAMA Intern Med. 2023;183(4):360-361. doi:10.1001/jamainternmed.2022.6792 Story From the Front Lines Apatient in their 70s with pancreatic adenocarcinoma with known hepatic metastases and peritoneal carcinomatosis was admitted from the emergency department due to gastric outlet obstruction. Prior to admission, the p...

Artificial Intelligence-Generated Manuscripts The healthcare industry is seeing remarkable technological progress. Several new tools have emerged that could significantly influence scientific research. One notable tool is RTutor, which combines the R programming language with GPT-3. This integration allows users to create R code and conduct analyses using plain language explanations of data and desired procedures. This means that even without coding skills, users c...

Original Investigation  November 11, 2023 Effect of Dietary Sodium on Blood Pressure: A Crossover Trial Deepak K. Gupta, Cora E. Lewis, Krista A. Varady, et al JAMA. Published online November 11, 2023. doi:10.1001/jama.2023.23651 Key Points Question  What is the impact of dietary sodium intake on blood pressure in middle-aged to elderly individuals? Findings  In this prospectively allocated diet order crossover study...

ORIGINAL ARTICLE A Placebo-Controlled Trial of Percutaneous Coronary Intervention for Stable Angina Christopher A. Rajkumar, Michael J. Foley, Fiyyaz Ahmed-Jushuf, et al N Engl J Med November 11, 2023DOI: 10.1056/NEJMoa2310610 Abstract BACKGROUND Percutaneous coronary intervention (PCI) is frequently performed to reduce the symptoms of stable angina. Whether PCI relieves angina more than a placebo procedure in patients who are not receiving antianginal m...

EDITORIAL| VOLUME 164, ISSUE 4, P812-813, OCTOBER 2023 Fluid Therapy in Sepsis: Does It Matter How Much? Jonathan A. Silversides, Bram Rochwerg Chest 2023; 164: 812-813 DOI:https://doi.org/10.1016/j.chest.2023.05.027 Although IV fluid resuscitation is a fundamental element of sepsis management, debate regarding the ideal volume, type, timing, and physiologic targets is ongoing. A number of large randomized trials have been published addressing this importan...