CRITICAL CARE: ORIGINAL RESEARCH| VOLUME 163, ISSUE 3, P533-542, MARCH 2023Download Full Issue Prolonged Prone Position Ventilation Is Associated With Reduced Mortality in Intubated COVID-19 Patients Daniel Okin, Ching-Ying Huang, George A. Alba, et al Chest 2023; 163: 533-542 Published:November 04, 2022 DOI:https://doi.org/10.1016/j.chest.2022.10.034 Background Prone position ventilation (PPV) is resource-intensive, yet the optimal strate...

CRITICAL CARE: ORIGINAL RESEARCH| VOLUME 163, ISSUE 4, P826-842, APRIL 2023Download Full Issue Days Spent at Home and Mortality After Critical Illness: A Cluster Analysis Using Nationwide Data Guillaume L. Martin, Alice Atramont, Marjorie Mazars, et al Chest 2023; 163: 826-842 Published:October 15, 2022 DOI:https://doi.org/10.1016/j.chest.2022.10.008 Background Beyond the question of short-term survival, days spent at home could be conside...

ICU Management & Practice, Volume 23 - Issue 2, 2023 Combined Extracorporeal Lung and Kidney Support in Fluid Overload During artificial organ support, kidney injury is multifactorial and related to the high severity of patients treated with extracorporeal membrane oxygenation (ECMO). The successful delivery of continuous renal replacement therapy (CRRT) during ECMO requires a clear prescription of the target solute clearance and fluid removal rate based on...

CRITICAL CARE: ORIGINAL RESEARCH| VOLUME 163, ISSUE 5, P1120-1129, MAY 2023Download Full Issue Differential Effect of Targeted Temperature Management Between 32 °C and 36 °C Following Cardiac Arrest According to Initial Severity of Illness: Insights From Two International Data Sets Jean Baptiste Lascarrou, Florence Dumas, Wulfran Bougouin, et al Chest 2023; 163: 1120-1129 Published:October 29, 2022 DOI:https://doi.org/10.1016/j.chest.2022.10.023...

CRITICAL CARE: ORIGINAL RESEARCH| VOLUME 164, ISSUE 1, P114-123, JULY 2023Download Full Issue Health Expectations and Quality of Life After Acute Respiratory Failure: A Multicenter Prospective Cohort Study Alison E. Turnbull, Emma M. Lee, Victor D. Dinglas, et al Chest 2023; 164: 114-123 Published:January 18, 2023 DOI:https://doi.org/10.1016/j.chest.2023.01.016 Background Patients often have high expectations for recovery after critical il...

CRITICAL CARE: ORIGINAL RESEARCH| VOLUME 163, ISSUE 6, P1425-1436, JUNE 2023Download Full Issue New and Persistent Sedative Prescriptions Among Older Adults Following a Critical Illness: A Population-Based Cohort Study Lisa D. Burry, Chaim M. Bell, Andrea Hill, et al Chest 2023; 163: 1425-1436 Published:January 04, 2023 DOI:https://doi.org/10.1016/j.chest.2022.12.033 Background ICU survivors often have complex care needs and can experience...

Functional Outcomes After Invasive Mechanical Ventilation for Older Adults Invasive mechanical ventilation can be a life-saving treatment, but it has poor short- and long-term outcomes for patients. In older adults, especially those with pre-existing long-term care needs due to functional and cognitive impairment, it may not be beneficial and could cause more suffering. Therefore, it is important to discuss with patients and families whether or not invasive mechani...

CRITICAL CARE: ORIGINAL RESEARCH| VOLUME 163, ISSUE 6, P1437-1447, JUNE 2023Download Full Issue Is Left Ventricular Systolic Dysfunction Associated With Increased Mortality Among Patients With Sepsis and Septic Shock? Siddharth Dugar, Ryota Sato, Sanchit Chawla, et al Chest 2023; 163: 1437-1447 Published:January 13, 2023 DOI:https://doi.org/10.1016/j.chest.2023.01.010 Background The impact of left ventricular (LV) systolic function on outc...

CHEST INFECTIONS: ORIGINAL RESEARCH| VOLUME 163, ISSUE 6, P1380-1389, JUNE 2023Download Full Issue Guideline-Concordant Antibiotic Therapy for the Hospital Treatment of Community-Acquired Pneumonia and 1-Year All-Cause and Cardiovascular Mortality in Older Adult Patients Surviving to Discharge Vicente F. Corrales-Medina, Carl van Walraven Chest 2023; 163: 1380-1389 Published:January 04, 2023 DOI:https://doi.org/10.1016/j.chest.2022.12.035 Bac...

Editorial  July 10, 2023 Translating Clinical Trial Results to Clinical Practice During a Pandemic Andre C. Kalil, Angela Huttner, Carlos A. Gomez JAMA. Published online July 10, 2023. doi:10.1001/jama.2023.11260 In February 2020, the National Institutes of Health (NIH) launched a public-private partnership, the Adaptive COVID-19 Treatment Trial (ACTT) network,1,2 followed in April 2020 by the Accelerating COVID-19 Therapeutic Interventi...