Original Investigation  Less Is More March 4, 2024 Clinical Outcomes of Rapid Respiratory Virus Testing in Emergency Departments: A Systematic Review and Meta-Analysis Tilmann Schober, Kimberly Wong, Gaëlle DeLisle, et al JAMA Intern Med. Published online March 4, 2024. doi:10.1001/jamainternmed.2024.0037 Key Points Question  Is rapid testing for respiratory viruses associated with patient treatment in the emergency department...

Original Investigation  March 4, 2024 Complication Rates of Central Venous Catheters: A Systematic Review and Meta-Analysis Bijan Teja, Nicholas A. Bosch, Calvin Diep, et al JAMA Intern Med. Published online March 4, 2024. doi:10.1001/jamainternmed.2023.8232 Key Points Question  What are the rates of complications from central venous catheter (CVC) use? Findings  This systematic review and meta-analysis of literature...

Editorials Reasons to avoid ultra-processed foods Carlos A Monteiro, Eurídice Martínez-Steele, Geoffrey Cannon BMJ 2024; 384 doi: https://doi.org/10.1136/bmj.q439 (Published 28 February 2024)Cite this as: BMJ 2024;384:q439 Ultra-processed foods damage health and shorten life Hundreds of epidemiological studies and meta-analyses have reported associations between ultra-processed food consumption and adverse health outcomes. In a linked paper (doi:10.1136/bmj...

Machine Learning for Predicting Unscheduled Returns to ED Hospitals utilise unscheduled return visit (URV) rates in emergency departments (EDs) to determine care quality. Higher rates lead to increased costs and longer wait times for patients who need immediate care. Frequent ED visits also contribute to overcrowding, causing treatment delays and higher mortality rates.  Developing predictive models is essential for early intervention to reduce ED revisits....

Research Added benefit and revenues of oncology drugs approved by the European Medicines Agency between 1995 and 2020: retrospective cohort study Francine Brinkhuis, Wim G Goettsch, Aukje K Mantel-Teeuwisse, et al BMJ 2024; 384 doi: https://doi.org/10.1136/bmj-2023-077391 (Published 28 February 2024)Cite this as: BMJ 2024;384:e077391 Abstract Objectives To evaluate the added benefit and revenues of oncology drugs, explore their association, and investi...

Research Ultra-processed food exposure and adverse health outcomes: umbrella review of epidemiological meta-analyses Melissa M Lane, Elizabeth Gamage, Shutong Du, et al BMJ 2024; 384 doi: https://doi.org/10.1136/bmj-2023-077310 (Published 28 February 2024)Cite this as: BMJ 2024;384:e077310 Abstract Objective To evaluate the existing meta-analytic evidence of associations between exposure to ultra-processed foods, as defined by the Nova food classificat...

Original Investigation  January 29, 2024 Efficacy of Electronic Cigarettes vs Varenicline and Nicotine Chewing Gum as an Aid to Stop Smoking: A Randomized Clinical Trial Hao-Xiang Lin, Zhao Liu, Peter Hajek, et al JAMA Intern Med. 2024;184(3):291-299. doi:10.1001/jamainternmed.2023.7846 Key Points Question  How do electronic cigarettes (ECs) as a stop-smoking aid compare with efficacy of varenicline and nicotine chewing gum? Findings&nb...

ORIGINAL ARTICLE Cognition and Memory after Covid-19 in a Large Community Sample Adam Hampshire, Adriana Azor, Christina Atchison, et al N Engl J Med 2024; 390:806-818DOI: 10.1056/NEJMoa2311330 Abstract BACKGROUND Cognitive symptoms after coronavirus disease 2019 (Covid-19), the disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), are well-recognized. Whether objectively measurable cognitive deficits exist and how long they per...

Environmental Sustainability and Antimicrobials Healthcare's environmental sustainability has become a pressing concern, with hospitals, clinical services, and the pharmaceutical industry identified as key contributors to environmental impact. Hospitals, in particular, are responsible for most greenhouse gas emissions, with the ICU being a significant consumer of resources like electricity, disposables, and pharmaceuticals. While most studies concentrate on these b...

ARTICLES|ONLINE FIRST Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults NCD Risk Factor Collaboration (NCD-RisC) Lancet Published:February 29, 2024 DOI: https://doi.org/10.1016/S0140-6736(23)02750-2 Summary Background Underweight and obesity are associated with adverse health outcomes throughout the life course. We estimated the ...