Research Delirium and incident dementia in hospital patients in New South Wales, Australia: retrospective cohort study Emily H Gordon, David D Ward, Hao Xiong, et al BMJ 2024; 384 doi: https://doi.org/10.1136/bmj-2023-077634 (Published 27 March 2024)Cite this as: BMJ 2024;384:e077634 Abstract Objectives To determine the strength and nature of the association between delirium and incident dementia in a population of older adult patients without dementia...

Editorial  April 1, 2024 Controlling Multidrug-Resistant Organisms Across Patient-Sharing Networks Christopher J. Crnich JAMA. Published online April 1, 2024. doi:10.1001/jama.2024.0267 Antimicrobial resistance is a major public health problem that threatens to reverse many of the medical therapy advances achieved over the past 4 decades.1 Infections caused by multidrug-resistant organisms (MDROs) are estimated to cause 35000 deaths in t...

Original Investigation  Hematology March 26, 2024 Accuracy of Diagnosing Heparin-Induced Thrombocytopenia Emil List Larsen, Henning Nilius, Jan-Dirk Studt, et al JAMA Netw Open. 2024;7(3):e243786. doi:10.1001/jamanetworkopen.2024.3786 Key Points Question  Is the current diagnostic practice for suspected heparin-induced thrombocytopenia (HIT) accurate? Findings  In this diagnostic study of 1318 patients suspected o...

Scientists Discover First New Antibiotic in Six Decades A ground-breaking class of antibiotics targeting drug-resistant Staphylococcus aureus (MRSA) bacteria has been discovered by applying transparent deep-learning models in medicine. Artificial intelligence (AI) is revolutionising the field, aiding scientists in unveiling the first novel antibiotics in six decades. Designated a priority-one critical pathogen by the World Health Organization, this organism has ...

Original Investigation  Infectious Diseases March 27, 2024 CDC’s Hospital-Onset Clostridioides difficile Prevention Framework in a Regional Hospital Network Nicholas A. Turner, Jay Krishnan, Alicia Nelson, et al JAMA Netw Open. 2024;7(3):e243846. doi:10.1001/jamanetworkopen.2024.3846 Key Points Question  Was implementation of the Centers for Disease Control and Prevention’s Strategies to Prevent Clostridioides d...

Original Investigation  April 1, 2024 Reducing Hospitalizations and Multidrug-Resistant Organisms via Regional Decolonization in Hospitals and Nursing Homes Gabrielle M. Gussin, James A. McKinnell, Raveena D. Singh, et al JAMA. Published online April 1, 2024. doi:10.1001/jama.2024.2759 Key Points Question  Is implementation of a regional hospital and nursing home decolonization collaborative (coordinated intervention adopted by p...

Computerised Decision Support Alerts for High-Risk Drug Combinations Existing clinical decision support systems (CDSSs) designed to prevent drug-drug interaction (DDI) often generate low-yield alerts, leading to alert fatigue among physicians and jeopardising patient safety.  A recent study focuses on the impact of tailoring DDI alerts to the ICU setting to reduce the frequency of high-risk drug combinations. The multicentre study aims to assess how customising...

Original Investigation  March 18, 2024 Text vs Patient Portal Messaging to Improve Influenza Vaccination Coverage: A Health System–Wide Randomized Clinical Trial Peter G. Szilagyi, O. Kenrik Duru, Alejandra Casillas, et al JAMA Intern Med. Published online March 18, 2024. doi:10.1001/jamainternmed.2024.0001 Key Points Question  Can either patient portal or text message reminders to patients abou...

Research Letter  March 25, 2024 Fatal Traffic Risks With a Total Solar Eclipse in the US Donald A. Redelmeier, John A. Staples JAMA Intern Med. Published online March 25, 2024. doi:10.1001/jamainternmed.2023.5234 A total solar eclipse occurs when the moon temporarily obscures the sun and casts a dark shadow across the earth. This astronomical spectacle has been described for more than 3 millennia and can be predicted with ...

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