ONLINE FIRST (FREE ACCESS) ESICM GUIDELINES GuidelinesEuropean Society of Intensive Care Medicine clinical practice guideline on fluid therapy in adult critically ill patients. Part 1: the choice of resuscitation fluidsArabi Y. M. et al TOPICAL COLLECTION "ICU TOOLBOX" EditorialEmpirical antimicrobials in the intensive care unitDe Bus L., Arvaniti K. and Sjövall F.Using echocardiography to predict fluid-responsiveness and manage the need for fluidsVi...

Original Investigation  Hematology May 31, 2024 Optimal Oral Iron Therapy for Iron Deficiency Anemia Among US Veterans Nilang Patel, Scott G. Silvey, Pradeep Arora, et al JAMA Netw Open. 2024;7(5):e2414305. doi:10.1001/jamanetworkopen.2024.14305 Key Points Question  What is the preferred oral iron supplementation strategy in patients with iron deficiency anemia (IDA)? Findings  I...

Understanding Respiratory Drive In ICU Tue, 30 Apr 2024 Understanding respiratory drive is crucial in managing critically ill patients. Recent data suggest  high and low respiratory drive can negatively impact patient outcomes. However,  “respiratory drive” can be ambiguous without understanding its determinants and underlying pathophysiology.  In critically ill patients, ventilatory demands reflected by respiratory centre o...

Original Investigation  Neurology May 31, 2024 Incidence of Traumatic Brain Injury in a Longitudinal Cohort of Older Adults Erica Kornblith, L. Grisell Diaz-Ramirez, Kristine Yaffe, et al JAMA Netw Open. 2024;7(5):e2414223. doi:10.1001/jamanetworkopen.2024.14223 Key Points Question  How common is traumatic brain injury (TBI) among older adults in the US? Findings  Over an 18-year...

Original Investigation  Critical Care Medicine May 31, 2024 In-Hospital vs 30-Day Sepsis Mortality at US Safety-Net and Non–Safety-Net Hospitals Anica C. Law, Nicholas A. Bosch, Yang Song, et al JAMA Netw Open. 2024;7(5):e2412873. doi:10.1001/jamanetworkopen.2024.12873 Key Points Question  Among patients with sepsis, is admission to a safety-net hospital associated with increased 30-day morta...

Editor's Note  May 28, 2024 Health Care Expenses and Household Resources for Families With Low Income Mitchell H. Katz, Raegan W. Durant, Deborah Grady JAMA Intern Med. Published online May 28, 2024. doi:10.1001/jamainternmed.2024.1473 Families must juggle many different expenses, including housing, utilities, food, transportation, medical care, and child care. When any of these expenses eat up too much of a family’s budget, there is a proble...

Errors in Nursing Interventions in Critically Ill Patients: Less is More In ICU Fri, 19 Apr 2024 In the treatment of critically ill patients, evidence-based nursing practices are essential, highlighting the need for precision in procedural management. This discussion identifies nine common errors encountered in clinical practice. Introduction Patient care is the essence of the nursing profession, focusing on the preservation, restoration, and promoti...

Original Investigation  Public Health May 28, 2024 Ratio of Red Blood Cell Distribution Width to Albumin Level and Risk of Mortality Meng Hao, Shuai Jiang, Jingdong Tang, et al JAMA Netw Open. 2024;7(5):e2413213. doi:10.1001/jamanetworkopen.2024.13213 Key Points Question  Is the ratio of red blood cell distribution width to albumin concentration (RAR) associated with mortality in the gener...

Editor's Note  May 28, 2024 Value in Optimizing the Components of App Interventions Before Final Testing Heather Gwynn Allore, Mitchell H. Katz JAMA Intern Med. Published online May 28, 2024. doi:10.1001/jamainternmed.2024.0833 Intensive care unit survivors are at increased risk of psychological distress, but few scalable interventions have been found effective. Interventions in behavioral health often have multiple components that may includ...

Original Investigation  Nutrition, Obesity, and Exercise March 27, 2024 Sitting Time Reduction and Blood Pressure in Older Adults: A Randomized Clinical Trial Dori E. Rosenberg, Weiwei Zhu, Mikael Anne Greenwood-Hickman, et al JAMA Netw Open. 2024;7(3):e243234. doi:10.1001/jamanetworkopen.2024.3234 Key Points Question  Is sitting time reduction an effective strategy for improving blood pressu...