Research Letter  March 18, 2024 Comparative Analysis of Multimodal Large Language Model Performance on Clinical Vignette Questions Tianyu Han, Lisa C. Adams, Keno K. Bressem, et al JAMA. Published online March 18, 2024. doi:10.1001/jama.2023.27861 Large language models (LLMs) have attracted attention for their ability to process text and other complex content.1,2 In medicine, an LLM-based advisory chat agent could assist in research, educatio...

AI-Driven Model Redefines Right Heart Health Assessment In a ground-breaking study, researchers from the Icahn School of Medicine at Mount Sinai have employed artificial intelligence (AI) to enhance the evaluation of the heart's right ventricle, responsible for pumping blood to the lungs. The study is published in the Journal of the American Heart Association. Utilising AI-enabled electrocardiogram (AI-ECG) analysis, the study reveals that electrocardiograms can...

Original Investigation  March 19, 2024 Stroke Risk After COVID-19 Bivalent Vaccination Among US Older Adults Yun Lu, Kathryn Matuska, Gita Nadimpalli, et al JAMA. 2024;331(11):938-950. doi:10.1001/jama.2024.1059 Key Points Question  Among adults aged 65 years or older, is the risk of stroke elevated in a time period immediately after administration of either brand of a COVID-19 bivalent vaccine compared with a later time period? ...

Original Investigation  March 18, 2024 Video Laryngoscopy vs Direct Laryngoscopy for Endotracheal Intubation in the Operating Room: A Cluster Randomized Clinical Trial Kurt Ruetzler, Sergio Bustamante, Marc T. Schmidt, et al JAMA. Published online March 18, 2024. doi:10.1001/jama.2024.0762 Key Points Question  What is the effect of initial video laryngoscopy or direct laryngoscopy on number of intubation attempts in patients bein...

Editorials Cancer trends in the UK Freddie Bray BMJ 2024; 384 doi: https://doi.org/10.1136/bmj.q504 (Published 13 March 2024)Cite this as: BMJ 2024;384:q504 Grounds for optimism but warning signs must not be ignored Cancer is a major public health problem in the UK, and in most high income countries. The disease is the leading cause of death in both men and women, and one in four people die prematurely from it at ages 30-69 years.1 A comprehensive asse...

Invited Commentary  March 13, 2024 Standardizing Resident Assessment and Competency—Milestones Matter Amanda C. Filiberto, Amalia Cochran JAMA Surg. Published online March 13, 2024. doi:10.1001/jamasurg.2024.0045 Smith et al1 present findings from an observational cohort study of early-career vascular surgeons and patient outcomes following endovascular aneurysm repair (EVAR), where lower mean Accreditation Council for Graduate Medical E...

Original Investigation  Public Health January 19, 2024 Occupational Sitting Time, Leisure Physical Activity, and All-Cause and Cardiovascular Disease Mortality Wayne Gao, Mattia Sanna, Yea-Hung Chen, et al JAMA Netw Open. 2024;7(1):e2350680. doi:10.1001/jamanetworkopen.2023.50680 Key Points Question  What are the health outcomes associated with prolonged occupational sitting in the context of various levels of physical activit...

ARTICLES| VOLUME 12, ISSUE 2, E201-E216, FEBRUARY 2024 The burden of bacterial antimicrobial resistance in the WHO African region in 2019: a cross-country systematic analysis Antimicrobial Resistance Collaborators Lancet Glob Health 2024; 12: E201-E216 Published: December 19, 2023 DOI:https://doi.org/10.1016/S2214-109X(23)00539-9 Summary Background A critical and persistent challenge to global health and modern health care is the threat of antimicrobial ...

ICU Management & Practice, Volume 24 - Issue 1, 2024 Defining Medicines Optimisation in the Intensive Care Unit Complex polypharmacy and pathophysiology are common in the intensive care unit (ICU). Medicines optimisation is essential to deliver safe, effective, and individualised pharmacotherapy. This is ideally performed by a specialised ICU pharmacist. Introduction Medicines are the most common intervention in healthcare and are a central compo...

Research 25 year trends in cancer incidence and mortality among adults aged 35-69 years in the UK, 1993-2018: retrospective secondary analysis Jon Shelton, Ewa Zotow, Lesley Smith, et al BMJ 2024; 384 doi: https://doi.org/10.1136/bmj-2023-076962 (Published 13 March 2024)Cite this as: BMJ 2024;384:e076962 Abstract Objective To examine and interpret trends in UK cancer incidence and mortality for all cancers combined and for the most common cancer sites ...