Original Investigation Caring for the Critically Ill Patient October 24, 2018 Effect of Early Sustained Prophylactic Hypothermia on Neurologic Outcomes Among Patients With Severe Traumatic Brain Injury: The POLAR Randomized Clinical Trial D. James Cooper, Alistair D. Nichol, Michael Bailey, et al JAMA. Published online October 24, 2018. doi:10.1001/jama.2018.17075 Abstract Importance 背景 After severe traumatic brain injury, induction of prophylactic hypothermia ...

SCCM and ACEP Release Joint Statement About the SSC Hour-1 Bundle 摘自http://www.survivingsepsis.org/News/Pages/SCCM-and-ACEP-Release-Joint-Statement-About-the-Surviving-Sepsis-Campaign-Hour-1-Bundle.aspx The Society of Critical Care Medicine (SCCM) and the American College of Emergency Physicians (ACEP) acknowledge concerns expressed about the recently released Surviving Sepsis Campaign (SSC) Hour-1 Bundle and the appropriateness of implementation in the United Stat...

Original Investigation Caring for the Critically Ill Patient October 24, 2018 Effect of Human Recombinant Alkaline Phosphatase on 7-Day Creatinine Clearance in Patients With Sepsis-Associated Acute Kidney Injury: A Randomized Clinical Trial Peter Pickkers, Ravindra L. Mehta, Patrick T. Murray, et al JAMA. Published online October 24, 2018. doi:10.1001/jama.2018.14283 Abstract Importance 背景 Sepsis-associated acute kidney injury (AKI) adversely affects long-term ...

Original Investigation Caring for the Critically Ill Patient October 24, 2018 Effect of High-Flow Nasal Oxygen vs Standard Oxygen on 28-Day Mortality in Immunocompromised Patients With Acute Respiratory Failure: The HIGH Randomized Clinical Trial Elie Azoulay, Virginie Lemiale, Djamel Mokart, et al JAMA. Published online October 24, 2018. doi:10.1001/jama.2018.14282 Abstract Importance 背景 High-flow nasal oxygen therapy is increasingly used for acute hypoxemic r...

Perspective > Medscape > Clinical Practice Guidelines Care of Adult Patients in the ICU Clinical Practice Guidelines (2018) Society of Critical Care Medicine Reviewed and summarized by Medscape editors October 04, 2018 Clinical practice guidelines for the Prevention and Management of Pain, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption in Adult Patients in the ICU were released in September 2018 by the Society for Critical Care Medicine.[1] Pain Use ...

Original Investigation Caring for the Critically Ill Patient October 24, 2018 Effect of a Low vs Intermediate Tidal Volume Strategy on Ventilator-Free Days in Intensive Care Unit Patients Without ARDS: A Randomized Clinical Trial Writing Group for the PReVENT Investigators JAMA. Published online October 24, 2018. doi:10.1001/jama.2018.14280 Abstract Importance 背景 It remains uncertain whether invasive ventilation should use low tidal volumes in critically ill pa...

Managing patients with refractory septic shock The Surviving Sepsis Guidelines provide a specific framework to treat patients with septic shock. These guidelines include the use of antimicrobial therapy, source control, fluid therapy and targeted vasoporessors. However, there is still a small proportion of patients that does not respond to these measures and consequently deteriorates into refractory shock and progressive multi-organ failure. Specific guidelines to manage...

INTENSIVE CARE MEDICINE ONLINE FIRST THIS WEEK Articles from RCTs released at LIVES 2018 Original ~ Impact of a multifaceted prevention programme on ventilator-associated pneumonia including selective oropharyngeal decontamination icTV interview with author Original ~ A multicentre randomised pilot trial on the effectiveness of different levels of cooling in comatose survivors of out-of-hospital cardiac arrest: the FROST-I trial  icTV interview with author Orig...

Original Investigation September 2018 Characteristics and Outcomes of Surgical Patients With Solid Cancers Admitted to the Intensive Care Unit Kathryn Puxty, Philip McLoone, Tara Quasim, et al JAMA Surg. 2018;153(9):834-840. doi:10.1001/jamasurg.2018.1571 Abstract Importance 背景 Within the surgical population admitted to intensive care units (ICUs), cancer is a common condition. However, clinicians can be reluctant to admit patients with cancer to ICUs owing to conc...

邀请您参加有关拯救脓毒症临床指南的在线调查 脓毒症及其各种并发症是危及人类健康的重要临床综合征，同时给社会带来了严重的经济负担。根据高收入国家和地区的流行病学数据预计，全球脓毒症的年发病率约为437例/10万人口，年发病人数超过3150万。专家估计，中低收入国家脓毒症的发病率可能更高。我国脓毒症发病率约为461例/10万人口，年发病人数约500万，死亡人数超过100万。 因此，增进医务人员对脓毒症的理解，是改善脓毒症患者临床预后的重要手段。 由加拿大McMaster大学Waleed Alhazzani医生负责的全球问卷调...