ICU Management & Practice, Volume 18 - Issue 1, 2018 Caring for critically ill immunocompromised patients: We can do better Professor Ellie Azoulay Professor of Medicine in Specialty Pulmonary Medicine and Critical Care, Saint Louis Teaching Hospital and Université Paris Diderot, France What are the major challenges in treating critically ill immunocompromised patients? Thank you for starting with the most important question. It is now demonstrated that critically i...

How can a smartphone be used for haemodynamic monitoring? The parameters of the Capstesia app are described. After taking a photo of the arterial waveform on the monitor screen, and cropping it to the signal of interest, the picture is sent to the Capstesia server via a mobile Internet connection. The heart rate and systolic and diastolic arterial pressures are manually entered into the app to determine the cardiac output (CO). After a few seconds, the PPV and CO values (...

Study: sepsis-induced DIC associated with high mortality Researchers in Japan conducted a multicentre retrospective observational study to investigate the epidemiology of disseminated intravascular coagulation (DIC) in patients with sepsis. They found that patients with DIC diagnosed by two consensus criteria had higher severity and in-hospital mortality than patients without DIC. The study results confirm the previous findings that, using consensus criteria, DIC is a com...

Research Association between patient outcomes and accreditation in US hospitals: observational study Miranda B Lam, Jose F Figueroa, Yevgeniy Feyman, et al.BMJ 2018; 363 doi: https://doi.org/10.1136/bmj.k4011 (Published 18 October 2018) Cite this as: BMJ 2018;363:k4011M Responses Abstract Objectives 目的 To determine whether patients admitted to US hospitals that are accredited have better outcomes than those admitted to hospitals reviewed through sta...

Intensive Care Medicine ONLINE FIRST THIS WEEK(FREE ACCESS) Original ~ Maryna Masyuk - Prognostic relevance of serum lactate kinetics in critically ill patients Systematic Review ~ Leona Bannon - The effectiveness of non-pharmacological interventions in reducing the incidence and duration of delirium in critically ill patients: a systematic review and meta-analysis Editorial ~ Peter Pickkers - Treatment with a polymyxin B filter to capture endot...

Practice | Rapid Recommendations Oxygen therapy for acutely ill medical patients: a clinical practice guideline Reed A C Siemieniuk, Derek K Chu, Lisa Ha-Yeon Kim, et al BMJ 2018; 363 doi: https://doi.org/10.1136/bmj.k4169 (Published 24 October 2018) Cite this as: BMJ 2018;363:k4169

Study: Nitric oxide decreases renal failure after cardiac surgery Results of a phase IIb prospective randomised controlled trial Prevention of Renal Failure by Nitric Oxide in Prolonged Cardiopulmonary Bypass showed that nitric oxide (NO) administered during surgery and for 24 hours afterwards was safe, and postoperatively reduced the incidence of acute kidney injury (AKI), transition to stage 3 chronic kidney disease, and major adverse kidney events at 30 days, 90 days, a...

Assessment of vocal cord movement by ultrasound in the ICU Zhengshang Ruan, Rongrong Ren, Wenwen Dong, et al Intensive Care Med 2018 Abstract Purpose 目的 Ultrasound can be used to non-invasively and rapidly examine airway conditions, but vocal cord visualization with the traditional approaches is poor. Our aim was to compare the accuracies of front-side transverse-axis ultrasound (FTU), lateral-side longitudinal-axis ultrasound (LLU), and the combination of both approac...

Alleviating inflammation: new inhibitor could treat ARDS in future A newly discovered OGG1 inhibitor has been found to decrease lung inflammation in mice and could in future treat acute respiratory distress syndrome (ARDS), sepsis and autoimmune diseases. The six-year study, by an international team of researchers, is published in Science. The research shows that the OGG1 protein, which is involved in repairing oxidated DNA, signals inflammation. The researchers set out t...

Intensive Care Medicine Erythromycin versus metoclopramide for post-pyloric spiral nasoenteric tube placement: a randomized non-inferiority trial Bei Hu, Xin Ouyang, Liming Lei, et al Intensive Care Med 2018 Abstract Purpose 目的 To determine whether erythromycin is non-inferior to metoclopramide in facilitating post-pyloric placement of self-propelled spiral nasoenteric tubes (NETs) in critically ill patients. 验证红霉素辅助重症患者自推进式螺旋型鼻肠管幽门后置管的...