Research Letter  Health and the 2024 US Election May 28, 2024 Financial Burden of Health Care in the Privately Insured US Population Sukruth A. Shashikumar, ZhaoNian Zheng, Karen E. Joynt Maddox, et al JAMA Intern Med. Published online May 28, 2024. doi:10.1001/jamainternmed.2024.1464 Improving health care affordability is a national priority, including for the nearly 180 million individuals with private ...

Decision-Making in Uncertainty: Time-Limited Trials In ICU Fri, 19 Apr 2024 An overview of time-limited trials (TLT), collaborative agreements between the treating team and the patient to apply life-sustaining therapies to help reduce prognostic uncertainty and foster trust between teams and patients and/or patient surrogates. Introduction Medical indication and a patient's consent form the basis of every diagnostic or therapeutic medical measure (Mi...

Original Investigation  May 23, 2024 Kidney Transplant Outcomes From Deceased Donors Who Received Dialysis Yumeng Wen, Sherry G. Mansour, Nityasree Srialluri, et al JAMA. Published online May 23, 2024. doi:10.1001/jama.2024.8469 Key Points Question  Are kidneys from deceased donors who underwent dialysis prior to kidney donation associated with adverse graft outcomes in kidney transplant recipie...

ONLINE FIRST (FREE ACCESS) LATEST ARTICLES OriginalMental health sequelae in survivors of cardiogenic shock complicating myocardial infarction. A population-based cohort studyFernando S. M. et al EditorialDiagnosing sepsis: where we’re at and where we’re goingZimmermann T., Brealey D. and Singer M. Lung ultrasound for diagnosis and management of ARDSSmit M. R., Mayo P. H. and Mongodi S. Caring for the dying patient in ICUSiddiqui S., Kretzer L. and Metaxa V...

Original Investigation  May 23, 2024 Hypertension and Kidney Function After Living Kidney Donation Amit X. Garg, Jennifer B. Arnold, Meaghan S. Cuerden, et al JAMA. Published online May 23, 2024. doi:10.1001/jama.2024.8523 Key Points Question  Do normotensive living kidney donors, compared with nondonors, have a higher risk of hypertension in the first 7 years following donation? Findings&nbs...

The Least Bad Decision: Crisis Standards of Care After the Pandemic In ICU Fri, 19 Apr 2024 COVID-19 was an emergency that lasted for years and left few regions of the world untouched. The pandemic shone a spotlight on both the strengths and weaknesses of our disaster planning. What worked, what did not, and how can we better plan for future emergencies? The COVID-19 pandemic forced hospitals and health systems around the world to confront shortages on ...

Executive Summary: Guidelines on Use of Corticosteroids in Critically Ill Patients With Sepsis, Acute Respiratory Distress Syndrome, and Community-Acquired Pneumonia Focused Update 2024 Corticosteroids in Sepsis and Septic Shock Recommendation. 1A) We suggest administering corticosteroids to adult patients with septic shock (conditional recommendation, low certainty). 1B) We recommend against administration of high dose/short duration corticosteroids (defined ...

ORIGINAL ARTICLE Video versus Direct Laryngoscopy for Urgent Intubation of Newborn Infants Lucy E. Geraghty, Emma A. Dunne, Caitríona M. Ní Chathasaigh, et al N Engl J Med Published May 5, 2024 DOI: 10.1056/NEJMoa2402785 Abstract BACKGROUND Repeated attempts at endotracheal intubation are associated with increased adverse events in neonates. When clinicians view the airway directly with a laryngoscope, fewer than half of first attempts are successful....

Original Investigation  Statistics and Research Methods May 22, 2024 Assessing the Risk of Bias in Randomized Clinical Trials With Large Language Models Honghao Lai, Long Ge, Mingyao Sun, et al JAMA Netw Open. 2024;7(5):e2412687. doi:10.1001/jamanetworkopen.2024.12687 Key Points Question  Are large language models reliable for assessing risk of bias (ROB) in randomized clinical trials (RCTs)? Findings  In this sur...

Anti-Inflammatory Therapies for Severe Community-Acquired Pneumonia In ICU Fri, 19 Apr 2024 Emerging evidence highlights the potential advantages of employing anti-inflammatory therapies like macrolide antibiotics and corticosteroids in managing severe community-acquired pneumonia (CAP). Although their use remains a subject of debate, recent findings indicate improved clinical outcomes, and support the adoption of a tailored approach that emphasises person...