[JAMA发表述评]:重新评价急性呼吸功能衰竭的呼吸支持:RENOVATE试验对临床实践的提示已关闭评论
Editorial
December 10, 2024
Reevaluating Respiratory Support in Acute Respiratory Failure—Insights From the RENOVATE Trial and Implications for Practice
Yonathan Freund, Amelie Vromant
JAMA. Published online December 10, 2024. doi:10.1001/jama.2024.25869
There is a fundamental question in emergency medicine: Is high-flow nasal oxygen an appropriate alternative to noninvasive ventilation across varied presentations of acute respiratory failur...
阅读全文
[NEJM发表论文]:来自HIV捐献者的肾移植安全性已关闭评论
ORIGINAL ARTICLE
Safety of Kidney Transplantation from Donors with HIV
Christine M. Durand, Allan Massie, Ph.D., Sander Florman, et al
N Engl J Med 2024;391:1390-1401
Abstract
BACKGROUND
Kidney transplantation from donors with human immunodeficiency virus (HIV) to recipients with HIV is an emerging practice. It has been performed since 2016 under the U.S. congressional HIV Organ Policy Equity Act and is currently approved for research only. The Departmen...
阅读全文
[JAMA发表论文]:医院普通病房患者的电子脓毒症预警已关闭评论
Original Investigation
Caring for the Critically Ill Patient
December 10, 2024
Electronic Sepsis Screening Among Patients Admitted to Hospital Wards: A Stepped-Wedge Cluster Randomized Trial
Yaseen M. Arabi, Abdulmohsen Alsaawi, Mohammed Alzahrani, et al
JAMA. Published online December 10, 2024. doi:10.1001/jama.2024.25982
Key Points
Question Does electronic sepsis screening based on quick ...
阅读全文
[JAMA发表述评]:高流量氧疗是所有急性呼吸功能衰竭患者的标准治疗吗?已关闭评论
Editorial
December 10, 2024
Is High-Flow Oxygen the Standard for All Patients With Acute Respiratory Failure?
Jean-Pierre Frat, Sylvain Le Pape, Arnaud W. Thille
JAMA. Published online December 10, 2024. doi:10.1001/jama.2024.25906
Hypoxemic acute respiratory failure denotes oxygenation failure attributable to various mechanisms, including ventilation-perfusion mismatch, increased shunt, diffusion impairment, and alveolar hypoventilation. Th...
阅读全文
[ICU Management & Practice]: 电子健康干预措施治疗ICU后综合征已关闭评论
eHealth Interventions to Treat Post-Intensive Care Syndrome
In ICU
Thu, 3 Oct 2024
Post Intensive Care Syndrome (PICS) is a critical issue affecting survivors of intensive care. PICS involves new or worsened physical, psychological, and cognitive impairments after critical illness, significantly impacting health-related quality of life (HRQoL), functional outcomes, and employment.
Critical care rehabilitation occurs in four phases: acute recov...
阅读全文
[JAMA发表论文]:急性呼吸功能衰竭患者的高流量鼻导管氧疗与无创机械通气已关闭评论
Original Investigation
Caring for the Critically Ill Patient
December 10, 2024
High-Flow Nasal Oxygen vs Noninvasive Ventilation in Patients With Acute Respiratory Failure: The RENOVATE Randomized Clinical Trial
RENOVATE Investigators and the BRICNet Authors
JAMA. Published online December 10, 2024. doi:10.1001/jama.2024.26244
Key Points
Question Is high-flow nasal oxygen noninferior to noninvasive ventilation for rate of en...
阅读全文
[ICU Management & Practice]: 重症ARDS患者ECMO治疗的生理效应已关闭评论
Physiologic Effects of ECMO in Patients With Severe ARDS
In ICU
Mon, 9 Sep 2024
In patients with severe acute respiratory distress syndrome (ARDS), managing gas exchange and avoiding ventilation-induced lung injury (VILI) are key challenges. Venovenous extracorporeal membrane oxygenation (ECMO) is used for severe ARDS with persistent hypoxaemia, effectively improving gas exchange and reducing ventilation pressures, though it doesn't support the cardiov...
阅读全文
[JAMA发表论文]:创伤患者早期限制性或自由性氧疗已关闭评论
Original Investigation
Caring for the Critically Ill Patient
December 10, 2024
Early Restrictive vs Liberal Oxygen for Trauma Patients: The TRAUMOX2 Randomized Clinical Trial
Tobias Arleth, Josefine Baekgaard, Volkert Siersma, et al
JAMA. Published online December 10, 2024. doi:10.1001/jama.2024.25786
Key Points
Question Does an early, 8-hour restrictive oxygen strategy compared with a liberal oxygen strategy in severely inj...
阅读全文
[ICU Management & Practice]: ESICM网络研讨会:手术后的心血管管理已关闭评论
ESICM Webinar – Cardiovascular Management After Surgery
In ICU
Tue, 1 Oct 2024
In a webinar at the ESICM Congress, Dr Aretha and Dr Garcia-Alvarez spoke about cardiovascular management after surgery. More specifically, Dr Aretha spoke about the management of post-operative atrial fibrillation, and Dr Garcia-Alvarez spoke about the importance of early application of vasopressin in septic shock patients.
Management of Postoperative Atrial Fibrillation Aft...
阅读全文
[Lancet Respir Med发表论文]:合并铜绿假单胞菌感染的支气管扩张患者吸入多粘菌素甲磺酸钠已关闭评论
ARTICLESVolume 12, Issue 10P787-798October 2024
Inhaled colistimethate sodium in patients with bronchiectasis and Pseudomonas aeruginosa infection: results of PROMIS-I and PROMIS-II, two randomised, double-blind, placebo-controlled phase 3 trials assessing safety and efficacy over 12 months
Charles S Haworth, Michal Shteinberg, Kevin Winthrop, et al
Lancet Respir Med 2024; 12: 787-798
Summary
Background
Chronic lung infection with Pseudomo...
阅读全文