Original Investigation  June 27, 2024 A More Selective vs a Standard Risk-Stratified, Heparin-Based, Obstetric Thromboprophylaxis Protocol Macie L. Champion, Christina T. Blanchard, Michelle Y. Lu, et al JAMA. 2024;332(4):310-317. doi:10.1001/jama.2024.8684 Key Points Question  Among patients with increased risk of postpartum venous thromboembolism, does a more selective protocol for initiating postpartum...

Effectiveness of Alternative Spontaneous Breathing Trial Techniques In ICU Tue, 11 Jun 2024 For intubated critically ill adults and children, minimising invasive mechanical ventilation to reduce complications is crucial. Early identification of when patients can safely transition to spontaneous breathing aims to shorten ventilation duration. However, clinicians must balance this with the risk of reintubation, which occurs in about 10% of cases, particu...

Original Investigation  July 31, 2024 Venous Thromboembolism Prophylaxis in High-Risk Pediatric Trauma Patients Amanda B. Witte, Kyle Van Arendonk, Carisa Bergner, et al JAMA Surg. Published online July 31, 2024. doi:10.1001/jamasurg.2024.2487 Key Points Question  Does the application of high-risk guidelines allow for safe and appropriate administration of venous thromboembolism (VTE) prophylaxi...

Research Personal protective effect of wearing surgical face masks in public spaces on self-reported respiratory symptoms in adults: pragmatic randomised superiority trial Runar Barstad Solberg, Atle Fretheim, Ingeborg Hess Elgersma, et ak BMJ 2024; 386 doi: https://doi.org/10.1136/bmj-2023-078918 (Published 24 July 2024) Cite this as: BMJ 2024;386:e078918 Abstract Objective To evaluate the personal protective effects of wearing versus not wearing s...

ONLINE FIRST (FREE ACCESS) LATEST ARTICLES OriginalThrombolysis before venoarterial ECMO for high-risk pulmonary embolism: a retrospective cohort studyLevy D. et al Effect of the 1-h bundle on mortality in patients with suspected sepsis in the emergency department: a stepped wedge cluster randomized clinical trialFreund Y. et al OPEN ACCESS ~ OriginalStandardised and automated assessment of head computed tomography reliably predicts poor functional outcome aft...

Ethical, Religious Barriers to Providing Medical Aid in Dying In ICU Sun, 2 Jun 2024 Recently published research by the University of Colorado Anschutz Medical Campus examines the prevalence and impact of physicians’ ethical or religious barriers to involvement in medical aid in dying (MAiD). MAiD is a multi-step process where a physician provides a terminally ill adult with decision-making capacity a lethal dose of medication to end their life. The re...

Effect of the 1-h bundle on mortality in patients with suspected sepsis in the emergency department: a stepped wedge cluster randomized clinical trial Freund, Y., de Abreu, M.C., Lebal, S. et al. Intensive Care Med 50, 1086–1095 (2024). https://doi.org/10.1007/s00134-024-07509-1 Abstract Purpose The efficacy of the 1-h bundle for emergency department (ED) patients with suspected sepsis, which includes lactate measurement, blood culture, broad-spectrum an...

Twenty percent human albumin solution fluid bolus administration therapy in patients after cardiac surgery-II: a multicentre randomised controlled trial Wigmore, G.J., Deane, A.M., Presneill, J.J. et al. Intensive Care Med 50, 1075–1085 (2024) https://doi.org/10.1007/s00134-024-07488-3 Abstract Purpose After cardiac surgery, fluid bolus therapy (FBT) with 20% human albumin may facilitate less fluid and vasopressor administration than FBT with crystalloid...

Calcium supplementation during trauma resuscitation: a propensity score-matched analysis from the TraumaRegister DGU® Dries Helsloot, Mark Fitzgerald, Rolf Lefering, et al Critical Care volume 28, Article number: 222 (2024) Abstract Background In major trauma patients, hypocalcemia is associated with increased mortality. Despite the absence of strong evidence on causality, early calcium supplementation has been recommended. This study investigates whether c...

Incidence of Traumatic Brain Injury in Older Adults In ICU Sun, 2 Jun 2024 According to a study by UC San Francisco and the San Francisco VA Health Care System, approximately 13% of older adults are diagnosed with traumatic brain injury (TBI), typically caused by ground-level falls. The findings are published in JAMA. Researchers tracked around 9,200 Medicare enrollees, with an average age of 75 at the study’s outset. The study aimed to identify fac...