现在位置 >首页 > 研究点评
0℃
Lung Histopathology: COVID-19 Compared to SARS, H1N1 The coronavirus disease has spread throughout the world and has resulted in many challenges for healthcare systems. It is a new disease with a significant burden of respiratory failure. This has led to questions about the pathogenesis and pulmonary pathology of COVID-19.  Patients with severe COVID-19 have respiratory failure with hypoxaemia, and acute bilateral pulmonary infiltrates. This is consistent with ...
阅读全文
0℃
ICU Management & Practice, Volume 20 - Issue 3, 2020 PCT-guided Antibiotic Stewardship in COVID-19 Patients Professor Michael Mansour is a physician-scientist with a research concentration in immune responses against invading pathogens. He attends on the Clinical Transplant Infectious Diseases and Immunocompromised Host Service at the Massachusetts General Hospital - Division of Infectious Diseases, where he cares for solid and stem cell transplant recipien...
阅读全文
0℃
Intensive Renal Replacement Therapy and Mechanical Ventilation Duration Acute kidney injury (AKI) is a global health issue, accounting for approximately two million deaths per year as well as presenting a heavy economic burden on healthcare systems. Hospital-acquired AKI is associated with increased risk of death and prolonged length of hospital stay. There are no effective treatments beyond supportive care for patients with AK from sepsis or hypotension. Sever...
阅读全文
0℃
Better Planning of COVID-19 Vaccine Trials The world is desperate for a reliable vaccine against COVID-19. However, the pressure for such rapid introduction could lead to deployment of a vaccine that may be weakly effective. In order to avoid this from happening, three issues must be considered when planning COVID-19 vaccine trials. These include proof of vaccine efficacy and worthwhile efficacy, whether these trials should prioritise single-vaccine or multivaccine ...
阅读全文
0℃
Editorials Convalescent plasma is ineffective for covid-19 Elizabeth B Pathak BMJ 2020; 371:m4072 doi: https://doi.org/10.1136/bmj.m4072  Lessons from the Placid Trial Convalescent plasma generated great enthusiasm in the earliest days of the coronavirus disease 2019 (covid-19) pandemic because of a plausible mechanism of action,1 its 100 year history of use in the treatment of other infectious diseases,2 and rapid availability from voluntary dono...
阅读全文
0℃
ICU Management & Practice, Volume 20 - Issue 3, 2020 Unmasking the Triumphs, Tragedies, and Opportunities of the COVID-19 Pandemic The COVID-19 pandemic has resulted in many changes to society and the practice of critical care medicine. Perhaps now is the time to address deficiencies in communication and decision-making that impact quality of care provided to older patients with serious illness. The COVID-19 pandemic has created a juxtaposition of triump...
阅读全文
0℃
ICU Management & Practice, Volume 20 - Issue 3, 2020 Nutritional Management of the Critically Ill Older Adult A review of available evidence and an overview of recommendations for the nutritional management of the critically ill older adult. Introduction Worldwide, there is a shift in the distribution of the population towards older ages. This shift is similarly being experienced in the Intensive Care Unit (ICU), with the median age of the entire ICU ...
阅读全文
0℃
COVID-19: Still Poorly Understood During the first few months of the coronavirus disease, it was being suggested that severe COVID-19 may represent a hyperimmune disorder, similar to secondary haemophagocytic lymphohistiocytosis (sHLH) and macrophage activation syndrome (MAS). Cytokine storm, elevated plasma levels, ferritin and inflammatory biomarkers are all typical signs of sHLH/MAS. But in many severe cases, T cells were found to be decreased, indicating T cell lym...
阅读全文
0℃
Corticosteroids and Mortality in COVID-19 Patients The use of corticosteroids to treat severe infections has been a controversy for quite a long time. Now, as we face the COVID-19 pandemic, clinical research on corticosteroids has received a significant push. During the first six months of 2020, 55 studies of corticosteroids for the treatment of COVID-19 have been registered. The RECOVERY trial has reported its findings demonstrating that 6mg/d of dexamethasone resu...
阅读全文
0℃
Epidemic Preparedness and Rapid Identification of Pathogens In recent years, infectious disease outbreaks have occurred with increasing frequency. Even though significant progress has been made to identify potentially dangerous pathogens, a lot still needs to be done. In particular,  diagnostics can play an important role in controlling epidemics. There is a need to develop and deploy diagnostics that can identify pathogens quickly and accurately. Diagnostic tests that...
阅读全文
×
腾讯微博