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Burnout Syndrome Among Critical Care Clinicians COVID-19 was declared a pandemic by the World Health Organization (WHO) in March 2020. Since then, nearly 100 million patients have been infected worldwide, and millions of deaths have been reported. While healthcare systems overall have been under immense pressure around the world, critical care teams, in particular, have shouldered significant psychological and moral burdens. Increased workload, risk of exposure,...
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Editorials Molnupiravir’s authorisation was premature James M Brophy BMJ 2022; 376 doi: https://doi.org/10.1136/bmj.o443 (Published 03 March 2022)Cite this as: BMJ 2022;376:o443 Regulatory decisions fall short of the wise stewardship required during a pandemic On 1 October 2021 Merck issued a press release1 reporting an interim analysis of Move-Out, a phase 3 randomised placebo controlled trial in unvaccinated adults with confirmed SARS-Co-V infection ...
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Viewpoint March 31, 2022 Reducing “COVID-19 Misinformation” While Preserving Free Speech William M. Sage, Y. Tony Yang JAMA. 2022;327(15):1443-1444. doi:10.1001/jama.2022.4231 Misinformation about risks, prevention, and treatment of COVID-19 has cost lives. Misinformation comes from many sources, with many motives for spreading and believing it. In caring capably and compassionately for patients, a substantial majority of health professionals and health c...
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Delirium Motor Subtypes in ICU Patients Delirium is the most common cerebral dysfunction in the ICU, affecting nearly one-third of patients. Based on its clinical manifestation, it can be divided into a hypoactive, hyperactive, or mixed motor subtype. Patients with hyperactive delirium are usually in an agitated state of mind and can display symptoms of aggression and restlessness. Patients with hypoactive delirium are in an apathetic state of mind and can display ...
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Editorials The benefits of large scale covid-19 vaccination Christopher Dye BMJ 2022; 377 doi: https://doi.org/10.1136/bmj.o867 (Published 27 April 2022)Cite this as: BMJ 2022;377:o867 New evidence confirms that fewer people die in better vaccinated communities The first covid-19 vaccines were administered under emergency use authorisation in December 2020, just one year into the pandemic, a “miracle” of pharmaceutical innovation that has saved an estimated...
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ICU Management & Practice, Volume 22 - Issue 1, 2022 Monitoring Postoperative Hypotension – A Futuristic Look at Patient Safety Post-operative hypotension is a frequent occurrence that is unrecognised with intermittent spot checks based monitoring in most hospital ward patients. Myocardial injury is strongly associated with hypotension in this period of recovery from surgery. Upgrading ward monitoring to portable, smart, and continuous systems with effectiv...
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Editorial March 8, 2022 Predictive Models for Acute Kidney Injury Following Cardiac Surgery: The Importance of Accurate and Actionable Prediction Marlies Ostermann, Nuttha Lumlertgul, Francis Perry Wilson JAMA. 2022;327(10):927-929. doi:10.1001/jama.2022.1823 Acute kidney injury (AKI) complicates recovery from cardiac surgery in up to 40% of patients; impairs the function of the heart, lungs, brain, and gut; and is associated with an increased r...
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Editorial April 7, 2022 Selecting Intermediate Respiratory Support Following Extubation in the Pediatric Intensive Care Unit Christopher M. Horvat, Martha A. Q. Curley, Timothy D. Girard JAMA. Published online April 7, 2022. doi:10.1001/jama.2022.4637 Prolonged invasive mechanical ventilation is associated with considerable morbidity among critically ill children, including secondary infections, exposure to potentially neurotoxic sedatives, and ...
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PICU Patients At-Risk for PARDS Approximately 2-4% of patients admitted to PICUs suffer from paediatric acute respiratory distress syndrome (PARDS). PARDS has a mortality rate of nearly 20% and has no specific treatment. Identifying children at risk of developing PARDS could potentially result in more targeted therapies to prevent disease progression and improve patient outcomes.  Children At Risk for PARDS (ARF-PARDS) are identified using criteria establis...
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Physical Rehabilitation in the ICU Approximately 65% of patients who survive critical illness suffer clinically detectable weakness due to muscle mass loss, myopathy and polyneuropathy. These changes occur early in ICU admission and are associated with prolonged weaning from mechanical ventilation and increased ICU and hospital length of stay. Clinical weakness is also associated with increased mortality both in the hospital and in the ICU and over the first year a...
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