Comment Kidney xenotransplantation—bridge to allotransplantation or destination treatment? Alexandre Loupy, Aurélie Sannier, Gabriel C Oniscu Lancet 2026; 408: 976-978 https://doi.org/10.1016/S0140-6736(26)01479-0 The shortage of human kidneys remains a central problem in transplantation, and many candidates die or are removed from the waiting list before an organ becomes available.1Genetically engineered porcine kidneys have long been proposed to expand th...

Surviving Sepsis Campaign: Guidelines for Management of Sepsis and Septic Shock 2026 In Sepsis Wed, 25 Mar 2026 The Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026, presented at the SCCM Congress this week, provide updated, evidence-based recommendations for the identification and management of sepsis across hospital, prehospital, and immediate post-hospital settings. Sepsis is defi...

Connecting ICU Data for Better Sepsis Care In Sepsis Wed, 4 Feb 2026 Sepsis remains a leading cause of mortality and long-term disability in intensive care, with outcomes varying widely across hospitals despite advances in technology and repeated guideline updates. One persistent barrier is the fragmentation of clinical data, which limits the ability of clinicians, researchers and health systems to learn systematically from real-world practice. The Eur...

French Military Transfusion Doctrine for Large-Scale Combat Operations In ICU Wed, 29 Apr 2026 A consensus article presents a revised French military transfusion doctrine tailored for large-scale combat operations (LSCO), addressing the substantial clinical, logistical, and organisational challenges posed by high-intensity warfare. The authors begin by situating the need for reform within the evolving geopolitical context, particularly the resurgenc...

Chlorhexidine vs Soap Bathing: Effects on ICU Outcomes In ICU Wed, 29 Apr 2026 An updated systematic review and meta-analysis evaluated whether daily bathing with 2% chlorhexidine gluconate (CHG) improves key clinical outcomes in critically ill patients compared with traditional soap-and-water (SAW) bathing. While CHG has recognised antimicrobial properties and has been widely studied for infection prevention, its broader impact on outcomes such as mor...

Explainable AI in Sepsis Prediction Faces Biomarker Gap In Sepsis Wed, 29 Apr 2026 Sepsis remains a major cause of morbidity and mortality in intensive care settings, requiring timely identification to support intervention. A recent systematic review published in International Journal of Medical Informatics evaluates machine learning approaches for early detection and prediction of sepsis, focusing on model explainability and alignment with c...

Gender Equality and Equity in Intensive Care In ICU Tue, 21 Apr 2026 An international study addressed gender equality and equity in intensive care medicine (ICM), a field where disparities persist despite increasing workforce diversity. The authors highlight that although women now comprise a substantial proportion of healthcare workers, leadership roles in intensive care remain disproportionately occupied by men.  Research has largely focused ...

nvited Commentary  Sleep, Burnout, and Surgery—Are Medical Errors an Adverse Effect? Jamie J. Coleman, Mitchell J. Cohen JAMA Surg Published Online: June 3, 2026 doi: 10.1001/jamasurg.2026.1807 Historically, sleep research and sleep hygiene recommendations have focused on sleep duration—the total amount of sleep obtained per night. Public health guidance has emphasized optimal ranges of sleep duration and promoted behaviors that help people achieve the...

Reporting of Withdrawal of Life-Sustaining Treatment in Acute Brain Injury Trials In ICU Tue, 21 Apr 2026 There is an under-recognised methodological challenge in randomised clinical trials (RCTs) involving patients with acute brain injury (ABI): the impact of withdrawal of life-sustaining treatment (WLST) on trial validity and interpretation. WLST represents a significant and often inadequately reported source of bias that can distort estimates of tre...

Emergency Critical Care: A Blind Spot? In ICU Tue, 21 Apr 2026 A recent article presents a conceptual analysis of emergency critical care (ECC), arguing that a substantial yet underrecognised phase of critical illness occurs before admission to the ICU. Although modern intensive care medicine has significantly improved outcomes in organ failure and complex illness, an increasing proportion of critically ill patients now receive prolonged, high-acuity t...