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Research Article: Timely completion of multiple life-saving interventions for traumatic haemorrhagic shock: a retrospective cohort study
引用格式: Mitra B, Bade-Boon J, Fitzgerald MC, Beck B, Cameron PA. Timely completion of multiple life-saving interventions for traumatic haemorrhagic shock: a retrospective cohort study. Burns Trauma. 2019; 7:22.
Abstract
Background
Early control of haemorrhage and optimisation of physiology are guiding principles of resuscit...
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Early Prediction of Sepsis From Clinical Data
Sepsis continues to be a leading cause of death in hospitalised patients. Approximately 1.7 million individuals develop sepsis each year in the US and of these, around 270,000 die from the infection. Sepsis affects nearly 30 million patients worldwide and nearly 6 million die from sepsis each year. Billions of dollars are required to manage sepsis, far exceeding the cost of most other healthcare disorders.
Sepsis is trea...
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The INCEPT Study: Impact of Post-Traumatic Cerebral Infarction
In the Hospital Senior Patient Rests on the Bed, Nurse in Ward Does Checkup. Recovering Man Sleeping in the Modern Hospital Ward.
Post-traumatic cerebral infarction (PTCI) is common after traumatic brain injury (TBI). TBI is a leading cause of mortality and morbidity mostly among young people, but its incidence is also increasing in older people, particularly in high-income countries. The outcome of a TB...
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Liberal or Conservative Oxygen Therapy for Acute Respiratory Distress Syndrome
Loic Barrot, Pierre Asfar, Frederic Mauny, et al
N Engl J Med 2020; 382:999-1008DOI: 10.1056/NEJMoa1916431
Abstract
BACKGROUND
In patients with acute respiratory distress syndrome (ARDS), the National Heart, Lung, and Blood Institute ARDS Clinical Trials Network recommends a target partial pressure of arterial oxygen (Pao2) between 55 and 80 mm Hg. Prospective validation of this ...
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Violent Attacks Against Emergency Physicians
young drunk man gets shirty with an ambulanceman at casualty
Violent attacks against emergency physicians remain a problem. While mass shootings at hospitals are quite rare, violent attacks against emergency physicians are becoming too common these days. There have been cases where emergency physicians have been knocked unconscious, physically assaulted, hit, bitten, kicked, and punched by patients. According to a recent ...
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Choosing the Best Blood Pressure Target for Vasopressor Therapy
John C. Marshall
JAMA 2020; 323: 931-933
Medical research drives innovation and improves outcomes. In cardiology, advances in diagnosis, prevention, and treatment reduced the 30-day mortality fromacutemyocardial infarction from 20% to 12.4% between 1995 and 2014.1 Similarly, for women diagnosed with breast cancer, 5-year survival has increased from74% to 88.5%over the past 4 decades2 in parallelwith ...
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A CT Scanner in Your Pocket?
x-ray lung image in tablet computer, stethoscope, medical document on desk of doctor. top view. medical technology concept.
Lung ultrasound (LUS) is still a young diagnostic tool. However, its use is growing quite rapidly. LUS is an important component of ultrasound courses around the world. It is also incorporated into many shock and hypoxia assessment protocols. LUS is now included as a part of the examination by the National Board of ...
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Effect of Reduced Exposure to Vasopressors on 90-Day Mortality in Older Critically Ill Patients With Vasodilatory Hypotension: A Randomized Clinical Trial
François Lamontagne, Alvin Richards-Belle, Karen Thomas, et al
JAMA. 2020;323(10):938-949. doi:10.1001/jama.2020.0930
Abstract
Importance
Vasopressors are commonly administered to intensive care unit (ICU) patients to raise blood pressure. Balancing risks and benefits of vasopressors is a challenge, parti...
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Optimal Approach to Fluid Resuscitation for Patients in Shock
Treatment of a patient in critical condition in the ICU ward
Initial fluid resuscitation practices for patients with haemodynamic shock remain controversial. There is significant variability in these practices, and the impact of this is still poorly understood. Overall, non-patient-centred resuscitation practices, conflicting treatments, variability, and failure to meet targets for initial resuscitation a...
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ARTICLES| VOLUME 8, ISSUE 3, P247-257, MARCH 01, 2020
Development and validation of parsimonious algorithms to classify acute respiratory distress syndrome phenotypes: a secondary analysis of randomised controlled trials
Pratik Sinha, Kevin L Delucchi, Daniel F McAuley, et al
Lancet Respir Med 2020; 8: 247-257
Summary
Background
Using latent class analysis (LCA) in five randomised controlled trial (RCT) cohorts, two distinct phenotypes of ...
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