{"id":31352,"date":"2026-07-21T04:24:00","date_gmt":"2026-07-20T20:24:00","guid":{"rendered":"https:\/\/csccm.org.cn\/?p=31352"},"modified":"2026-07-21T05:43:41","modified_gmt":"2026-07-20T21:43:41","slug":"nejm%e5%8f%91%e8%a1%a8%e8%ae%ba%e6%96%87%ef%bc%9a%e7%be%8e%e5%9b%bd%e5%8c%bb%e9%99%a2%e7%9a%84%e5%8c%bb%e7%96%97%e7%9b%b8%e5%85%b3%e6%84%9f%e6%9f%93%ef%bc%9a2023-vs-2015","status":"publish","type":"post","link":"https:\/\/csccm.org.cn\/?p=31352","title":{"rendered":"[NEJM\u53d1\u8868\u8bba\u6587]\uff1a\u7f8e\u56fd\u533b\u9662\u7684\u533b\u7597\u76f8\u5173\u611f\u67d3\uff1a2023 vs 2015"},"content":{"rendered":"\n<p><a href=\"https:\/\/www.nejm.org\/browse\/nejm-article-type\/original-article\">ORIGINAL ARTICLE<\/a><\/p>\n\n\n\n<h1 class=\"wp-block-heading\">Health Care\u2013Associated Infections in U.S. Hospitals, 2023 versus 2015<\/h1>\n\n\n\n<h3 class=\"wp-block-heading\">Nora\u00a0Chea,\u00a0Rongxia\u00a0Li,\u00a0Taniece\u00a0Eure,\u00a0et al<\/h3>\n\n\n\n<h3 class=\"wp-block-heading\">N Engl J Med\u00a02026;395:255-266<\/h3>\n\n\n\n<h3 class=\"wp-block-heading\">DOI: 10.1056\/NEJMoa2510881<\/h3>\n\n\n\n<h2 class=\"wp-block-heading\">Abstract<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">BACKGROUND<\/h3>\n\n\n\n<p>Prevalence surveys in U.S. hospitals showed that on any given day, 1 of 25 patients had a health care\u2013associated infection in 2011, as compared with 1 of 31 patients in 2015. We repeated the survey in 2023 to assess changes in the prevalence of such infections.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">METHODS<\/h3>\n\n\n\n<p>Using established methods, 10 Emerging Infections Program (EIP) sites recruited up to 25 hospitals each. Hospitals selected a survey day between May 1 and September 30, 2023. EIP staff reviewed medical records of randomly selected patients to identify health care\u2013associated infections using National Healthcare Safety Network definitions. We described patient and hospital characteristics, compared the prevalence of health care\u2013associated infections in 2023 and 2015, and estimated the national burden of health care\u2013associated infections in 2023.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">RESULTS<\/h3>\n\n\n\n<p>In 2023, of 13,653 patients in 218 hospitals, 355 (2.6%; 95% confidence interval [CI], 2.3 to 2.9) had at least one health care\u2013associated infection, as compared with 394 of 12,299 patients (3.2%; 95% CI, 2.9 to 3.5) in 199 hospitals in 2015. Approximately 60% of the health care\u2013associated infections were not associated with devices or procedures. Among 151 hospitals in both surveys, patients were less likely to have a health care\u2013associated infection in 2023 than in 2015, after adjustment for other factors (risk ratio, 0.73; 95% CI, 0.63 to 0.85). We estimated that there were 518,000 health care\u2013associated infections (95% CI, 494,500 to 542,000) in U.S. hospitals in 2023.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><a href=\"https:\/\/csccm.org.cn\/wp-content\/uploads\/2026\/07\/nejmoa2510881_t1.jpg\"><img decoding=\"async\" loading=\"lazy\" width=\"843\" height=\"1024\" src=\"https:\/\/csccm.org.cn\/wp-content\/uploads\/2026\/07\/nejmoa2510881_t1-843x1024.jpg\" alt=\"\" class=\"wp-image-31353\" srcset=\"https:\/\/csccm.org.cn\/wp-content\/uploads\/2026\/07\/nejmoa2510881_t1-843x1024.jpg 843w, https:\/\/csccm.org.cn\/wp-content\/uploads\/2026\/07\/nejmoa2510881_t1-247x300.jpg 247w, https:\/\/csccm.org.cn\/wp-content\/uploads\/2026\/07\/nejmoa2510881_t1-768x933.jpg 768w, https:\/\/csccm.org.cn\/wp-content\/uploads\/2026\/07\/nejmoa2510881_t1-1264x1536.jpg 1264w, https:\/\/csccm.org.cn\/wp-content\/uploads\/2026\/07\/nejmoa2510881_t1-1685x2048.jpg 1685w, https:\/\/csccm.org.cn\/wp-content\/uploads\/2026\/07\/nejmoa2510881_t1.jpg 1711w\" sizes=\"(max-width: 843px) 100vw, 843px\" \/><\/a><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><a href=\"https:\/\/csccm.org.cn\/wp-content\/uploads\/2026\/07\/nejmoa2510881_t2.jpg\"><img decoding=\"async\" loading=\"lazy\" width=\"888\" height=\"1024\" src=\"https:\/\/csccm.org.cn\/wp-content\/uploads\/2026\/07\/nejmoa2510881_t2-888x1024.jpg\" alt=\"\" class=\"wp-image-31354\" srcset=\"https:\/\/csccm.org.cn\/wp-content\/uploads\/2026\/07\/nejmoa2510881_t2-888x1024.jpg 888w, https:\/\/csccm.org.cn\/wp-content\/uploads\/2026\/07\/nejmoa2510881_t2-260x300.jpg 260w, https:\/\/csccm.org.cn\/wp-content\/uploads\/2026\/07\/nejmoa2510881_t2-768x885.jpg 768w, https:\/\/csccm.org.cn\/wp-content\/uploads\/2026\/07\/nejmoa2510881_t2-1333x1536.jpg 1333w, https:\/\/csccm.org.cn\/wp-content\/uploads\/2026\/07\/nejmoa2510881_t2-1777x2048.jpg 1777w, https:\/\/csccm.org.cn\/wp-content\/uploads\/2026\/07\/nejmoa2510881_t2.jpg 1999w\" sizes=\"(max-width: 888px) 100vw, 888px\" \/><\/a><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><a href=\"https:\/\/csccm.org.cn\/wp-content\/uploads\/2026\/07\/nejmoa2510881_t3-scaled.jpg\"><img decoding=\"async\" loading=\"lazy\" width=\"1024\" height=\"690\" src=\"https:\/\/csccm.org.cn\/wp-content\/uploads\/2026\/07\/nejmoa2510881_t3-1024x690.jpg\" alt=\"\" class=\"wp-image-31355\" srcset=\"https:\/\/csccm.org.cn\/wp-content\/uploads\/2026\/07\/nejmoa2510881_t3-1024x690.jpg 1024w, https:\/\/csccm.org.cn\/wp-content\/uploads\/2026\/07\/nejmoa2510881_t3-300x202.jpg 300w, https:\/\/csccm.org.cn\/wp-content\/uploads\/2026\/07\/nejmoa2510881_t3-768x517.jpg 768w, https:\/\/csccm.org.cn\/wp-content\/uploads\/2026\/07\/nejmoa2510881_t3-1536x1035.jpg 1536w, https:\/\/csccm.org.cn\/wp-content\/uploads\/2026\/07\/nejmoa2510881_t3-2048x1380.jpg 2048w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/a><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><a href=\"https:\/\/csccm.org.cn\/wp-content\/uploads\/2026\/07\/nejmoa2510881_t4.jpg\"><img decoding=\"async\" loading=\"lazy\" width=\"1024\" height=\"982\" src=\"https:\/\/csccm.org.cn\/wp-content\/uploads\/2026\/07\/nejmoa2510881_t4-1024x982.jpg\" alt=\"\" class=\"wp-image-31356\" srcset=\"https:\/\/csccm.org.cn\/wp-content\/uploads\/2026\/07\/nejmoa2510881_t4-1024x982.jpg 1024w, https:\/\/csccm.org.cn\/wp-content\/uploads\/2026\/07\/nejmoa2510881_t4-300x288.jpg 300w, https:\/\/csccm.org.cn\/wp-content\/uploads\/2026\/07\/nejmoa2510881_t4-768x736.jpg 768w, https:\/\/csccm.org.cn\/wp-content\/uploads\/2026\/07\/nejmoa2510881_t4-1536x1472.jpg 1536w, https:\/\/csccm.org.cn\/wp-content\/uploads\/2026\/07\/nejmoa2510881_t4.jpg 1711w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/a><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><a href=\"https:\/\/csccm.org.cn\/wp-content\/uploads\/2026\/07\/nejmoa2510881_t5-scaled.jpg\"><img decoding=\"async\" loading=\"lazy\" width=\"1024\" height=\"970\" src=\"https:\/\/csccm.org.cn\/wp-content\/uploads\/2026\/07\/nejmoa2510881_t5-1024x970.jpg\" alt=\"\" class=\"wp-image-31357\" srcset=\"https:\/\/csccm.org.cn\/wp-content\/uploads\/2026\/07\/nejmoa2510881_t5-1024x970.jpg 1024w, https:\/\/csccm.org.cn\/wp-content\/uploads\/2026\/07\/nejmoa2510881_t5-300x284.jpg 300w, https:\/\/csccm.org.cn\/wp-content\/uploads\/2026\/07\/nejmoa2510881_t5-768x727.jpg 768w, https:\/\/csccm.org.cn\/wp-content\/uploads\/2026\/07\/nejmoa2510881_t5-1536x1454.jpg 1536w, https:\/\/csccm.org.cn\/wp-content\/uploads\/2026\/07\/nejmoa2510881_t5-2048x1939.jpg 2048w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/a><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\">CONCLUSIONS<\/h3>\n\n\n\n<p>The prevalence of health care\u2013associated infections was lower in 2023 than in 2015, with 1 of 38 patients on any given day having such an infection; however, the burden of health care\u2013associated infections in U.S. hospitals continued to be high. A majority of the health care\u2013associated infections that were identified were not associated with a device or procedure. (Funded by the Emerging Infections Program cooperative agreement from the Centers for Disease Control and Prevention.)<\/p>\n","protected":false},"excerpt":{"rendered":"<p>ORIGINAL ARTICLE Health Care\u2013Associated Infections in U [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[32,23],"tags":[],"_links":{"self":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/31352"}],"collection":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=31352"}],"version-history":[{"count":1,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/31352\/revisions"}],"predecessor-version":[{"id":31358,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/31352\/revisions\/31358"}],"wp:attachment":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=31352"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=31352"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=31352"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}