{"id":31005,"date":"2026-08-21T04:46:00","date_gmt":"2026-08-20T20:46:00","guid":{"rendered":"https:\/\/csccm.org.cn\/?p=31005"},"modified":"2026-08-21T05:44:05","modified_gmt":"2026-08-20T21:44:05","slug":"intensive-care-med%e5%8f%91%e8%a1%a8%e8%ae%ba%e6%96%87%ef%bc%9a%e6%89%b6%e6%89%8b%e6%a4%85%e4%bd%93%e4%bd%8d%e5%af%b9%e6%8e%a5%e5%8f%97%e5%91%bc%e5%90%b8%e6%94%af%e6%8c%81%e6%b2%bb%e7%96%97%e7%9a%84","status":"publish","type":"post","link":"https:\/\/csccm.org.cn\/?p=31005","title":{"rendered":"[Intensive Care Med\u53d1\u8868\u8bba\u6587]\uff1a\u6276\u624b\u6905\u4f53\u4f4d\u5bf9\u63a5\u53d7\u547c\u5438\u652f\u6301\u6cbb\u7597\u7684\u81ea\u4e3b\u547c\u5438ICU\u60a3\u8005\u6c27\u5408\u7684\u5f71\u54cd"},"content":{"rendered":"\n<h1 class=\"wp-block-heading\">Effects of out-of-bed armchair positioning on oxygenation in spontaneously breathing ICU patients receiving respiratory support: a randomized controlled trial<\/h1>\n\n\n\n<h3 class=\"wp-block-heading\">Fossat, G., Muller, L., Seguin, A.\u00a0<em>et al.<\/em><\/h3>\n\n\n\n<h3 class=\"wp-block-heading\"><em>Intensive Care Med<\/em>\u00a0(2026).<\/h3>\n\n\n\n<h3 class=\"wp-block-heading\">https:\/\/doi.org\/10.1007\/s00134-026-08453-y<\/h3>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"Abs1\">Abstract<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">Purpose<\/h3>\n\n\n\n<p>Comparing the effects of an out-of-bed armchair position versus an in-bed semi-recumbent position on oxygenation in spontaneously breathing intensive care unit (ICU) patients, receiving respiratory support is a common practice with limited supported evidence.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Methods<\/h3>\n\n\n\n<p>A single-center randomized controlled trial in spontaneously breathing adult ICU patients receiving invasive pressure support ventilation, high-flow nasal oxygen, or non-invasive ventilation. Patients were assigned to armchair or semi-recumbent in-bed positioning for 3&nbsp;h. Arterial blood gasses were obtained immediately before and after positioning. PaO<sub>2<\/sub>\/FiO<sub>2<\/sub>&nbsp;(<em>P\/F<\/em>) changes were analyzed with a linear mixed-effects model including group, time, and their interaction, adjusted for stratification variables.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Results<\/h3>\n\n\n\n<p>284 patients were randomized (146 and 138 in the armchair and bed groups, respectively). Baseline\u00a0<em>P\/F<\/em>\u00a0ratios did not differ between groups. A significant interaction between group and time was observed (<em>p<\/em>\u2009=\u20090.002). In the armchair group, the\u00a0<em>P\/F<\/em>\u00a0ratio increased by 13\u00a0mm Hg (95% CI 1\u201324), whereas it decreased by 13\u00a0mm Hg (95% CI \u2212\u00a025 to \u2212\u00a01) in the bed group. The post-positioning marginal mean\u00a0<em>P\/F<\/em>\u00a0ratio was higher in the armchair group (241\u00a0mm Hg, 95% CI 214\u2013268) than in the bed group (206\u00a0mm Hg, 95% CI 179\u2013233;\u00a0<em>p<\/em>\u2009=\u20090.004). No serious adverse events occurred. Minor adverse events were more frequent in the armchair group but had minimal impact on positioning duration.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"https:\/\/media.springernature.com\/lw685\/springer-static\/image\/art%3A10.1007%2Fs00134-026-08453-y\/MediaObjects\/134_2026_8453_Figa_HTML.png?as=webp\" alt=\"\"\/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"https:\/\/media.springernature.com\/full\/springer-static\/image\/art%3A10.1007%2Fs00134-026-08453-y\/MediaObjects\/134_2026_8453_Fig1_HTML.png?as=webp\" alt=\"\"\/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"https:\/\/media.springernature.com\/full\/springer-static\/image\/art%3A10.1007%2Fs00134-026-08453-y\/MediaObjects\/134_2026_8453_Fig2_HTML.png?as=webp\" alt=\"\"\/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"https:\/\/media.springernature.com\/full\/springer-static\/image\/art%3A10.1007%2Fs00134-026-08453-y\/MediaObjects\/134_2026_8453_Fig3_HTML.png?as=webp\" alt=\"\"\/><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\">Conclusion<\/h3>\n\n\n\n<p>In spontaneously breathing ICU patients receiving respiratory support, out-of-bed armchair positioning was associated with higher oxygenation after 3&nbsp;h than remaining in a semi-recumbent position, with no serious adverse events observed.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">ClinicalTrials.gov-Identifier<\/h3>\n\n\n\n<p>NCT04446559.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Effects of out-of-bed armchair positioning on oxygenati [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[32,23],"tags":[],"_links":{"self":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/31005"}],"collection":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=31005"}],"version-history":[{"count":1,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/31005\/revisions"}],"predecessor-version":[{"id":31006,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/31005\/revisions\/31006"}],"wp:attachment":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=31005"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=31005"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=31005"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}