{"id":30680,"date":"2026-07-09T04:23:00","date_gmt":"2026-07-08T20:23:00","guid":{"rendered":"https:\/\/csccm.org.cn\/?p=30680"},"modified":"2026-07-09T06:09:16","modified_gmt":"2026-07-08T22:09:16","slug":"nejm%e4%b8%b4%e5%ba%8a%e5%8c%bb%e5%ad%a6%e5%bd%b1%e5%83%8f%ef%bc%9a%e4%ba%9a%e6%80%a5%e6%80%a7%e9%aa%a8%e9%ab%93%e7%82%8e%e5%af%bc%e8%87%b4%e7%9a%84%e9%aa%a8%e5%86%85%e8%84%93%e8%82%bf","status":"publish","type":"post","link":"https:\/\/csccm.org.cn\/?p=30680","title":{"rendered":"[NEJM\u4e34\u5e8a\u533b\u5b66\u5f71\u50cf]\uff1a\u4e9a\u6025\u6027\u9aa8\u9ad3\u708e\u5bfc\u81f4\u7684\u9aa8\u5185\u8113\u80bf"},"content":{"rendered":"\n

IMAGES IN CLINICAL MEDICINE<\/a><\/p>\n\n\n\n

Intraosseous Abscess from Subacute Osteomyelitis<\/h1>\n\n\n\n

Haijian\u00a0Li<\/h3>\n\n\n\n

N Engl J Med\u00a02026;394:1529<\/h3>\n\n\n\n

DOI: 10.1056\/NEJMicm2514540<\/h3>\n\n\n\n
\"\"<\/a><\/figure>\n\n\n\n

A previously healthy 16-year-old girl presented to the orthopedic clinic with a 1-month history of left ankle pain and an 11-day history of fever. The physical examination was notable for generalized tenderness to palpation of the left ankle, along with a limited active and passive range of motion. Plain radiographs of the ankle (Panel A, anteroposterior view; Panel B, lateral view) showed an ill-defined, radiolucent lesion (arrow) on the distal tibia that crossed the physeal scar (the radio-opaque line at the site of the fused growth plate). There was associated soft-tissue swelling but no fracture or periosteal reaction. Owing to concern about an aggressive infection or neoplasm, magnetic resonance imaging (MRI) of the leg was performed. The images showed a lesion measuring 14 mm by 16 mm by 12 mm on the distal tibia (Panel C, coronal view; Panel D, sagittal view); the lesion was hypointense and surrounded by a hyperintense sclerotic rim, a finding known as the penumbra sign, which is specific for subacute osteomyelitis. A diagnosis of an intraosseous abscess \u2014 also known as a Brodie\u2019s abscess \u2014 from subacute osteomyelitis was made. The patient was treated with surgical d\u00e9bridement and a course of antibiotic agents. Metagenomic sequencing of the d\u00e9brided tissue identified\u00a0Salmonella enterica<\/em>. At 3 months after completion of the course of antibiotics, the patient\u2019s symptoms had completely resolved.<\/p>\n","protected":false},"excerpt":{"rendered":"

IMAGES IN CLINICAL MEDICINE Intraosseous Abscess from S […]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[16,13],"tags":[],"_links":{"self":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/30680"}],"collection":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=30680"}],"version-history":[{"count":2,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/30680\/revisions"}],"predecessor-version":[{"id":30685,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/30680\/revisions\/30685"}],"wp:attachment":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=30680"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=30680"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=30680"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}