{"id":30052,"date":"2026-03-28T04:52:00","date_gmt":"2026-03-27T20:52:00","guid":{"rendered":"https:\/\/csccm.org.cn\/?p=30052"},"modified":"2026-03-28T06:40:16","modified_gmt":"2026-03-27T22:40:16","slug":"lancet%e5%8f%91%e8%a1%a8%e8%ae%ba%e6%96%87%ef%bc%9a%e8%ba%ab%e4%bd%93%e6%b4%bb%e5%8a%a8%e9%87%8f%e5%92%8c%e4%b9%85%e5%9d%90%e6%97%b6%e9%97%b4%e7%9a%84%e5%be%ae%e5%b0%8f%e6%94%b9%e5%8f%98%e8%83%bd","status":"publish","type":"post","link":"https:\/\/csccm.org.cn\/?p=30052","title":{"rendered":"[Lancet\u53d1\u8868\u8bba\u6587]\uff1a\u8eab\u4f53\u6d3b\u52a8\u91cf\u548c\u4e45\u5750\u65f6\u95f4\u7684\u5fae\u5c0f\u6539\u53d8\u80fd\u591f\u9884\u9632\u6b7b\u4ea1\u98ce\u9669"},"content":{"rendered":"\n

Articles<\/p>\n\n\n\n

Deaths potentially averted by small changes in physical activity and sedentary time: an individual participant data meta-analysis of prospective cohort studies<\/h1>\n\n\n\n

Ulf\u00a0Ekelund,\u00a0Jakob\u00a0Tarp,\u00a0Ding\u00a0Ding, et al<\/h3>\n\n\n\n

Lancet 2026; 407: 339-349<\/h3>\n\n\n\n

https:\/\/doi.org\/10.1016\/S0140-6736(25)02219-6<\/h3>\n\n\n\n

Summary<\/h2>\n\n\n\n

Background<\/h3>\n\n\n\n

The effects of small, realistic changes in physical activity and sedentary behaviour on population-level mortality are unclear. We aimed to estimate the proportion of deaths preventable by 5-min and 10-min incremental increases in moderate-to-vigorous intensity physical activity (MVPA) and 30-min and 60-min reductions in daily sedentary time.<\/p>\n\n\n\n

Methods<\/h3>\n\n\n\n

We did an individual participant data meta-analysis of prospective cohort studies. We included studies with device-measured physical activity and sedentary time. We estimated the proportion of deaths prevented (potential impact fractions; PIFs) by changes in (1) the approximately 20% least active participants (high-risk approach) and (2) all participants except the approximately 20% most active (population-based approach). We calculated PIFs from adjusted hazard ratios estimated for 5-min and 10-min increases in MVPA and 30-min and 60-min reductions in sedentary time from observed levels across the activity distribution.<\/p>\n\n\n\n

Findings<\/h3>\n\n\n\n

We included seven cohorts from Norway, Sweden, and the USA (n=40\u2009327; 4895 deaths). Data from the UK Biobank (n=94\u2009719; 3487 deaths) were analysed separately. A 5-min\/day increase in MVPA in the least active participants might prevent 6\u00b70% (95% CI 4\u00b73\u20137\u00b74) of all deaths. A similar increase in MVPA in all participants except the most active might prevent 10\u00b70% (6\u00b73\u201313\u00b74) of all deaths. Reducing sedentary time by 30 min\/day might prevent 3\u00b70% (2\u00b70\u20134\u00b71) of all deaths in the high-risk approach and 7\u00b73% (4\u00b78\u20139\u00b76) in the population-based approach. Results from the UK Biobank were of a smaller magnitude but still substantial\u2014eg, reducing sedentary time by 30 min\/day in all except the most active participants was associated with preventing 4\u00b75% (2\u00b78\u20136\u00b71) of total deaths.<\/p>\n\n\n\n

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Interpretation<\/h3>\n\n\n\n

Small and realistic increases in MVPA of 5 min\/day might prevent up to 6% of all deaths in a high-risk approach and 10% of all deaths in population-based approach. Reducing sedentary time by 30 min\/day might prevent a smaller, but still meaningful, proportion of deaths in the two risk scenarios.<\/p>\n\n\n\n

Funding<\/h3>\n\n\n\n

None.<\/p>\n","protected":false},"excerpt":{"rendered":"

Articles Deaths potentially averted by small changes in […]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[32,23],"tags":[],"_links":{"self":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/30052"}],"collection":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=30052"}],"version-history":[{"count":2,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/30052\/revisions"}],"predecessor-version":[{"id":30054,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=\/wp\/v2\/posts\/30052\/revisions\/30054"}],"wp:attachment":[{"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=30052"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=30052"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/csccm.org.cn\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=30052"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}